Journals / MN Kardiyoloji / 2001 / Cilt: 8 - Sayı: 1

A new parameter in interpretation of exercise test in women: QTc dispersion and QT dispersion ratio difference

Kadınlarda egzersiz testinin yorumlanmasında yeni bir parametre: Egzersiz ve istirahat QTc dispersiyon ve QT dispersiyon oranı farkı

Pages
29–34
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In addition, the evaluation of QTD variables may provide information about the incidence of CAD.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: This study was planned in order to investigate the value of QT dispersion (QTD) parameters which were reported to increase the diagnostic accuracy of exercise test in women.
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Key Findings & Data:It has been reported that, the increase of QTD occurred due to repolarization defect because of transient ischemia obtained by standart 12 leads ECG, and the changes during exercise and the differences between exercise and rest increase the accuracy of exercise test in the diagnosis of coronary artery disease (CAD).
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Conclusion & Impact:In addition, the evaluation of QTD variables may provide information about the incidence of CAD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Elektrokardiyografi · Göğüs ağrısı · Koroner anjiyografi

Abstract

AIM: This study was planned in order to investigate the value of QT dispersion (QTD) parameters which were reported to increase the diagnostic accuracy of exercise test in women. The diagnostic accuracy of exercise test in distinguishing diagnosis of chest pain in women is low. It has been reported that, the increase of QTD occurred due to repolarization defect because of transient ischemia obtained by standart 12 leads ECG, and the changes during exercise and the differences between exercise and rest increase the accuracy of exercise test in the diagnosis of coronary artery disease (CAD). MATERIAL AND METHODS: Ninety seven women patient were evaluated for the diagnosis of chest pain, who were performed coronary angiography and exercise test. QTD was calculated using the measurements of the highest and lowest values of QT length obtained by ECG during peak exercise. The QTc using Bazett's equation, and the QTD ratio (QTDR) using QT/RR were calculated, and QTcD and QTD ratio were obtained. The difference of QTcD and QTD ratio was determined by extracting the rest values from the exercise values. RESULTS: The normal coronary (n=48), single vessel CAD (n=24) and multivessel CAD (n=25) groups were compared. Although the calculated QTD parameters were found to be significantly increased in patients with CAD (p<0.001), the parameters were found higher in the patients with multivessel CAD (p<0.05). With the parameters QTcD<60 ms and QTDO<10%, the more sensitivity and specificity were obtained compared to ST segment depression. The highest diagnostic accuracy was obtained with the QTD parameters were calculated from the differences of rest and exercise values. With the difference of QTcD>15 ms and QTD ratio>5% resulted with better diagnostic accuracy (sensitivtiy, specificity, negative and positive predictor values are as follows respectively; 84-88-84-87% and 84-96-85-95%). CONCLUSION: The use of QTD parameters as variables of ECG which is easily obtainable ,in evaluation of exercise ECG in women, increases the diagnostic accuracy of exercise test. In addition, the evaluation of QTD variables may provide information about the incidence of CAD.

Özet

AMAÇ: Kadınlarda egzersiz testinin tanısal doğruluğunu arttırdığı bildirilen QT dispersiyon (QTD) parametrelerinin değerini araştırmak amacıyla bu çalışmayı planladık. Egzersiz testinin kadınlarda göğüs ağrısının ayırıcı tanısında tanısal doğruluğu düşüktür. Standart 12 derivasyonlu EKG ile elde edilen, geçici iskemiye bağlı repolarizasyon bozukluğu sonucu gelişen QTD artışının, egzersiz değişiklikleri ve egzersiz istirahat farklarının, egzersiz testinin koroner arter hastalığı (KAH)'nın tanısındaki doğruluğunu arttırdığı bildirilmektedir. GEREÇ VE YÖNTEM: Göğüs ağrısının ayırıcı tanısı için egzersiz testi ve koroner anjiyografi yapılan 97 kadın hasta değerlendirildi. EKG'de zirve egzersizde elde edilen en büyük ve küçük QT mesafeleri ölçülerek QTD hesaplandı. Bazett's eşitliği ile QTc ve QT/RR orantısı ile QT oranı hesaplanarak QTcD ve QTD oranı elde edildi. Egzersiz değerlerinden istirahat değerleri çıkarılarak QTcD ve QTD oranı farkı bulundu. BULGULAR: Normal koroner (n=48), tek damar (n=24) ve çok damar KAH (n=25) tespit edilen olgu grupları karşılaştırıldı. Hesaplanan QTD parametreleri, KAH bulunanlarda belirgin olarak artmış olmasına ilave olarak (p 60 ms ve QTD oranı>%10 parametreleri ile, ST segment çökmesine göre daha iyi duyarlılık ve özgüllük oranları elde edildi. En yüksek tanısal doğruluk ise egzersiz ve istirahat farklarından elde QTD parametreleri ile elde edildi. QTcD farkı>15ms ve QTD oranı farkı>%5 olması, daha iyi tanısal doğruluk ile sonuçlandı (duyarlılık, özgüllük, negatif ve pozitif öngörü değerleri sıra ile; %84-88-84-8 7 ve %84-96-85-95). SONUÇ: Kadınlarda egzersiz EKG'sinin değerlendirilmesinde kolaylıkla ölçülebilen EKG değişkeni QTD parametrelerinin kullanılması ile egzersiz testinin tanısal doğruluğu artmaktadır. Bunun yanında, QTD değişkenlerinin değerlendirilmesi, KAH'nın yaygınlığı hakkında da bilgi sağlayabilir.

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Cite This Article

ÖZDEMİR, K., ALTUNKESER, B. B., AYDIN, M., ÖZEREN, A., DANIŞ, G., GÖK, H. (2001). A new parameter in interpretation of exercise test in women: QTc dispersion and QT dispersion ratio difference. MN Kardiyoloji, Cilt: 8 - Sayı: 1, 29–34. https://ajindex.com/articles/297784

References (1)

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