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Journals / MN Kardiyoloji / 2003 / Cilt: 10 - Sayı: 2

Importance of serial cardiac markers measurements for the evaluation of in-hospital cardiac complications after percutaneous coronary intervention in patients with acute coronary

Akut koroner sendromlu hastalarda perkutan koroner girişim sonrası hastane içi kardiyak komplikasyonların değerlendirilmesinde seri kardiyak marker ölçümünün önemi

Mahmut AÇIKEL
ALPAY ARIBAŞ
Mustafa YILMAZ
Hüseyin ŞENOCAK
ŞULE KARAKELLEOĞLU
Sebahattin ATEŞAL
Necip ALP
Pages
90–96
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: We think that noninvasive assessment of in-hospital cardiac complications after primary PCI in ACS might be possible with serial measurements of cardiac markers.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: We investigated the relationships between in-hospital cardiac complications and serial measurements of cardiac troponin I (cTnI), myoglobin and creatine kinase-MB (CK-MB) after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS).
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Key Findings & Data:Material and Methods: This study included 92 patients with ACS performed primary PCI. cTnI, myoglobin and CK-MB levels were measured in venous blood samples obtained from patients shortly before (0), 6, 12, and 24 hours after PCI.
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Conclusion & Impact:Conclusion: We think that noninvasive assessment of in-hospital cardiac complications after primary PCI in ACS might be possible with serial measurements of cardiac markers.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Koroner hastalık · Kreatin kinaz · Miyoglobin

Abstract

Aim: We investigated the relationships between in-hospital cardiac complications and serial measurements of cardiac troponin I (cTnI), myoglobin and creatine kinase-MB (CK-MB) after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS). Material and Methods: This study included 92 patients with ACS performed primary PCI. cTnI, myoglobin and CK-MB levels were measured in venous blood samples obtained from patients shortly before (0), 6, 12, and 24 hours after PCI. In hospital period after PCI, patients were divided into 2 groups: the cases with (Group A, n=22) and without (Group B, n=70) cardiac complications. Results: Mean cTnI (p<0.01), myoglobin (p<0.001) and CK-MB (p<0.05) values obtained 24 hours after PCI were higher in group A than in group B. In group B, mean myoglobin values measured at the 12th and 24th hours were found to be significantly decreased when compared to both 0th and 6th hours values (p<0.001). Conclusion: We think that noninvasive assessment of in-hospital cardiac complications after primary PCI in ACS might be possible with serial measurements of cardiac markers.

Özet

Amaç: Biz akut koroner sendromlu (AKS) hastalarda perkutan koroner girişim (PKG) sonrası kanda seri olarak ölçülen kardiyak troponin I (cTnI), miyoglobin ve kreatin kinaz-MB (CK-MB) ile hastane içi dönemde kardiyak komplikasyonlar arasındaki ilişkileri araştırdık. Gereç ve Yöntem: Bu çalışmaya primer PKG yapılan AKS'lu 92 hasta alındı. PKG'den hemen önce (0.saat), 6, 12 ve 24 saat sonra alınan venöz kan örneklerinden cTnI, miyoglobin ve CK-MB düzeyleri ölçüldü. Hastalar PKG sonrası hastane içi dönemde 2 gruba ayrıldı: Kardiyak komplikasyon olan hastalar (grup A, n=22) ve kardiyak komplikasyon olmayan hastalar (grup B, n=70). Bulgular: PKG'den 24 saat sonra ölçülen cTnI (p<0.01), miyoglobin (p<0.001) ve CK-MB'nin (p<0.05) ortalama değerleri grup A'da grup B'e göre anlamlı olarak yüksek bulundu. Grup B'de 12. ve 24. saatlerde ölçülen ortalama miyoglobin değeri 0. ve 6. saatlerdeki değerlere göre anlamlı olarak azalmış idi (p<0.001). Sonuç: Biz AKS'lu hastalarda primer PKG sonrası hastane içi dönemde kardiyak komplikasyonların invazif olmayan yöntemle değerlendirilmesinin seri kardiyak marker ölçümü ile mümkün olabileceğini kanısındayız.

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Cite This Article

AÇIKEL, M., ARIBAŞ, A., YILMAZ, M., ŞENOCAK, H., KARAKELLEOĞLU, Ş., ATEŞAL, S., ALP, N. (2003). Importance of serial cardiac markers measurements for the evaluation of in-hospital cardiac complications after percutaneous coronary intervention in patients with acute coronary. MN Kardiyoloji, Cilt: 10 - Sayı: 2, 90–96. https://ajindex.com/articles/297658

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