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Journals / MN Oftalmoloji / 2005 / Cilt: 12 - Sayı: 1

Senile cataract progression and ascorbic acid

Senil katarakt ilerlemesi ve askorbik asit

Nil İrem UÇGUN
Zuhal YILDIRIM
Özlem Evren ABBASOĞLU
Ümmühan ÖZEL
Cenk Zeki FİKRET
Ayşe BİLGEHAN
Emin GÜRSEL
Pages
10–12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Nevertheless, no correlation could be established between aqueous humor levels of ascorbic acid and senile cataract progression.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To investigate whether there is a role for ascorbic acid in the progression of cataract.
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Key Findings & Data:Material and Methods: Twenty patients with mature cataract and 21 patients with posterior subcapsular or nuclear cataracts.
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Conclusion & Impact:Nevertheless, no correlation could be established between aqueous humor levels of ascorbic acid and senile cataract progression.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Katarakt · Hastalık ilerlemesi · Askorbik asit

Abstract

Purpose: To investigate whether there is a role for ascorbic acid in the progression of cataract. Material and Methods: Twenty patients with mature cataract and 21 patients with posterior subcapsular or nuclear cataracts. Were included in the study.Patients with ophthalmic conditions other than cataract that may influence ascorbic acid levels were excluded. A small volume of aqueous humor was aspirated at the begining of phacoemulsification cataract surgery. Ascorbic acid concentration was evaluated in aqueous samples using a spectrophotometric method. Results: Ascorbic acid levels of aqueous humor was 31.28±24.12 mg/mg in group 1 and 25.59±13.02 mg/ml in group 2. The difference between two group was not statistically significant, (p>0.05) Conclusion: The development of senile cataract has been associated with a number of risk factors. Nevertheless, no correlation could be established between aqueous humor levels of ascorbic acid and senile cataract progression.

Özet

Amaç: Senil katarakt ilerlemesinde askorbik asitin etkisini değerlendirmek. Gereç ve Yöntem: Matür kataraktı olan 20 hasta (grup 1) ve arka subkapsüler veya nükleer kataraktı olan 21 hasta (grup 2) çalışmaya alındı. Katarakt dışında askorbik asit seviyesini etkileyen durumlar çalışma dışı bırakıldı. Fakoemülsifikasyon ile katarakt ameliyatı başlangıcında az miktarda humor aköz aspire edildi. Aközde, askorbik asit konsantrasyonları spektrofotometrik yöntem ile tespit edildi. Bulgular: Humor aköz askorbik asit seviyeleri grup 1'de 31.28±24.12 mg/ml ve grup 2'de 25.59±13.02 mg/ml idi. Her iki grup arasındaki fark istatistiksel olarak anlamlı değildi (p>0.05). Sonuç: Senil katarakt oluşumunda pek çok risk faktörü etkilidir. Bununla birlikte aközdeki askorbik asit seviyesi ile senil katarakt ilerlemesi arasında ilişki saptanmamıştır.

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Cite This Article

UÇGUN, N. İ., YILDIRIM, Z., ABBASOĞLU, Ö. E., ÖZEL, Ü., FİKRET, C. Z., BİLGEHAN, A., GÜRSEL, E. (2005). Senile cataract progression and ascorbic acid. MN Oftalmoloji, Cilt: 12 - Sayı: 1, 10–12. https://ajindex.com/articles/297075

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