SavedAdd your journal

Journals / MN Oftalmoloji / 2000 / Cilt: 7 - Sayı: 2

Relationship of optic disc size and age with thickness of retinal nerve fiber layer

Peripapiller sinir lifi tabakası kalınlığı ile optik disk alanı ve yaş arasındaki ilişki

Ahmet Barış TOPRAK
Ömer Faruk YILMAZ
Pages
150–153
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Optic disc size and age should be considered when the peripapillary RNFL thickness is measured in patients with glaucoma or any other progressive optic neuropathy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:PURPOSE: To evaluate the relation of the optic disc size and age with the thickness of the retinal nerve fibre layer (RNFL) in normal white subjects by means of scanning laser polarimetry and tomography MATERIAL AND METHOD: Optic disc size and RNFL thickness values of 38 normal white subjects of both sexes aged 20 to 78 were measured using a confocal scanning laser ophthalmoscope (TopSS, Laser Diagnostic Technologies, Inc.) and a confocal scanning laser polarimeter (NFA, Laser Diagnostic Technologies, Inc.).
📊
Key Findings & Data:RESULTS: Age showed a significant correlation with the integral of the total RNFL thickness (R= -0.341, p<0.05).
💡
Conclusion & Impact:Optic disc size and age should be considered when the peripapillary RNFL thickness is measured in patients with glaucoma or any other progressive optic neuropathy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Oftalmoskopi · Optik disk · Optik sinir

Abstract

PURPOSE: To evaluate the relation of the optic disc size and age with the thickness of the retinal nerve fibre layer (RNFL) in normal white subjects by means of scanning laser polarimetry and tomography MATERIAL AND METHOD: Optic disc size and RNFL thickness values of 38 normal white subjects of both sexes aged 20 to 78 were measured using a confocal scanning laser ophthalmoscope (TopSS, Laser Diagnostic Technologies, Inc.) and a confocal scanning laser polarimeter (NFA, Laser Diagnostic Technologies, Inc.). One eye was randomly selected for statistical analysis. The effects of optic disc size and age on total and regional RNFL thickness were evaluated. RESULTS: Age showed a significant correlation with the integral of the total RNFL thickness (R= -0.341, p<0.05). The optic disc size showed a significant correlation with the integral of the total, superior and inferior quadrant RNFL thickness (R=0.425, p<0.05), (R=0.361, p<0.05), (R=0.468, p<0.05). CONCLUSION: The thickness of total as well as superior and inferior quadrant peripapillary RNFL as measured by scanning laser polarimetry increased significantly with an increase in optic disc size. The total cross sectional area occupied by RNF decreased significantly with an increase in age. Optic disc size and age should be considered when the peripapillary RNFL thickness is measured in patients with glaucoma or any other progressive optic neuropathy.

Özet

AMAÇ: Peripapiller retinal sinir lifi tabakası (RSLT) kalınlığı ile yaş ve optik disk atanı arasındaki ilişkinin tarayıcı laser polarimetre ve konfokal tarayıcı laser tomografi cihazları aracılığı ile araştırılması amaçlandı. GEREÇ VE YÖNTEM: Otuzsekiz adet 20-78 yaşlan arasındaki normal bireyin optik disk alanı, konfokal tarayıcı laser tomografi (TopSS, Laser Diagnostic Technologies, Inc.) kullanılarak, peripapiller RSLT kalınlıkları ise tarayıcı laser polarimetre (NFA, Laser Diagnostic Technologies, Inc.) kullanılarak ölçüldü. Bireylerin yalnızca bir göz ölçüm değerleri istatistiksel değerlendirme için rastlantısal olarak seçildi. İstatistiksel yöntem olarak doğrusal regresyon analizi, tek yönlü ANOVA ve Scheffe testleri uygulandı. BULGULAR: Yaş ile toplam RSLT kalınlığı arasında istatistiksel olarak anlamlı bir ilişki saptandı (R=-0.341, p<0.05). Optik disk alanı ile toplam, superior ve inferior kadran RSLT kalınlıkları arasında anlamlı bir ilişki saptandı (R=0.425, p<0.05), (R=0.361, p<0.05), (R=0.468, p<0.05). SONUÇLAR: RSLT kalınlığı ile optik disk alanı arasında toplam, superior ve inferior kadran kalınlıkları başta olmak üzere doğrusal bir ilişki mevcuttur. Optik disk alanı büyüdükçe peripapiller RSLT kalınlığı artmaktadır. Yaş ile toplam RSLT kalınlığı arasında negatif bir doğrusal ilişki saptanmıştır. Yaş ilerledikçe toplam RSLT kalınlığı azalmaktadır. Bu durumda glokom ve diğer ilerleyici optik nöropatileri değerlendirmek amacı ile RSLT kalınlığı ölçüldüğünde, optik disk alanının ve yaşın RSLT kalınlık değerleri üzerinde etkili olduğu göz önüne alınmalıdır.

🔖

Cite This Article

TOPRAK, A. B., YILMAZ, Ö. F. (2000). Relationship of optic disc size and age with thickness of retinal nerve fiber layer. MN Oftalmoloji, Cilt: 7 - Sayı: 2, 150–153. https://ajindex.com/articles/296423

References (16)

  1. Sommer A, Miller NR, Pollack I et al. The nen/e fiber layer in the diagnosi5 of glaucama. Arch Ophthalmol 1977; 95:2149-6
  2. Ouigley HA, Miller NR, George T. Clinica evaulation of nerve fiber layer atrophy as an indicator of glaucomatous optic nerve damage. Arch Ophthalmol 1980; 98:1564-71
  3. Armaly MF, Saydeggh RH. The cup/disc ratio. Arch Ophthalmol 1969; 82:193
  4. IWata K. Opththalmoscopy in the deteetion of optic disc and retinal nerve fiber layer change in early glaucoma. Surv Ophthalmology 1989; 33:447-8
  5. Ouigley HA, Addicks EM. Quantitative studies of retinal nerve fiber layer defeets. Arch Ophthalmol 1982; 100:807-14
  6. Sommer A, Quigley HA, Robin AL, Miller R, Katz J, Arkell S. Evaluation of nerve fiber layer assessment. Arch Ophthalmol 1984; 102:1722-71
  7. Sommer A, Katz J. ûuigley HA et al. Clinically deteetable nerve fiber atrophy precedes the onset of glaucamatous visual field loss. Arch Ophthalmol 1991; 109:77-83
  8. Chi QM, Tomita G, Inazumi K, Hayakawa T, Ido T, Kitazawa Y. Evaulatian of the effect of aging on the retinal nerve fiber layer thickness using scanning laser polarimetry. J Glaucoma 1995; 4:406-13
  9. Tjon-Fo-Sang MJ, Lemij HG. The sensitivity and spesicifity of nerve fiber layer measurements in glaucoma as determined with scanning laser polarîmetry. Am J Ophthalmol 1997; 123:62-8
  10. Weinreb RN, Shakiba S, Sample PA et al. Association between quantitative nerve fiber layer measurement and visual field loss in glaucoma. Am J Ophthalmol 1995; 120:732-8
  11. Dreher AW, Reiter K. Retinal laser eüipsometry; a new method of measusing the retinal nerve fiber layer thickness distribution? Clin Vision Sci 1992:7:481-3
  12. Weinreb RN, Dreher QW, Coleman A, Ouigley H, Shaw B, Reiter K. Histopathologic validation of Fourier-ellİpsometry measurements of retinal nerve fiber layer thickness. Arch Ophthalmol 1990; 108:557-60
  13. Weinreb RN, Shakiba S, Zangwill L. Scanning laser polarimetry to measure the retinal nerve fiber layer of normal and glaucomataus eyes. Am J Ophthalmol 1995; 119:627-36
  14. Weinreb RN, Shakiba S, Sample PA et al. Association between quantitative nerve fiber layer measurement and visual field loss in glaucama. Am J Ophthalmol 1995; 120:732-8
  15. Chauhan BC, LeBlanc RP, McCormick TA, Rogers JB. Test-retest variablity of topographic measurements with confocai scanning laser tomography in patients with glaucoma and control subjects. Am J Ophthalmol 1994; 118:9-15
  16. Kruse FE, Burk ROW, Völcker H-E, Zinser