Journals / MN Oftalmoloji / 2012 / Cilt: 19 - Sayı: 3

Central and peripheric corneal thicknesses in seronegative and seropositive rheumatologic diseases

Seronegatif ve seropozitif romatolojik hastalıklarda santral ve periferik kornea kalınlığı

Pages
137–142
DOI
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Conclusion: In our study it was found that, the central and peripheral corneal thicknesses were thinner in seronegative RA patients when compared to seropositive RA and seronegative AS patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The aim of this study was to evaluate the central and peripheric corneal thicknesses with anterior segment optical coherance tomography (OCT) in seronegative (rheumatoid factor (RF) negative) and seropositive (RF positive) rheumotogic diseases.
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Key Findings & Data:Material and Method: Sixty-six eyes (group 1) of 33 seronegative rheumatoid artritis (RA) patients, 50 eyes (group 2) of 25 patients with seropositive RA, and 52 eyes of 26 patients with seronegative ankylosing spondylitis (AS) were composed in this study.
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Conclusion & Impact:Conclusion: In our study it was found that, the central and peripheral corneal thicknesses were thinner in seronegative RA patients when compared to seropositive RA and seronegative AS patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of this study was to evaluate the central and peripheric corneal thicknesses with anterior segment optical coherance tomography (OCT) in seronegative (rheumatoid factor (RF) negative) and seropositive (RF positive) rheumotogic diseases. Material and Method: Sixty-six eyes (group 1) of 33 seronegative rheumatoid artritis (RA) patients, 50 eyes (group 2) of 25 patients with seropositive RA, and 52 eyes of 26 patients with seronegative ankylosing spondylitis (AS) were composed in this study. Sixty eyes of 30 healthy subjects were evaluated as the control group. All subjects were performed central corneal thickness (CCT) and temporal peripheric corneal thickness (TPCT) measurements with the anterior segment OCT. The results were compared between groups. Results: The mean age was 56.30 ±7.9 years in group 1, 53.66±9.22 years in group 2, 43.73 ±10.86 years in group 3 and 51±7,82 years in the control group. In group 1 the mean CCT was 518.53 ±31.61&#956;m, and the mean TPCT was 704.87 ±46.81 &#956;m. In group 2 the mean CCT was 536.33 ±35.12&#956;m, while the mean TPCT was 723.47 ±54.57 &#956;m. In group 3 the mean CCT was measured as 539.52 ±28.14 &#956;m, and the mean TPCT was measured as 742.46 ±44.45 &#956;m. In the control group the mean CCT and TPCT was 540.59 ±38.94&#956;m and 740.64 ±42.28 &#956;m respectively. The mean CCT and TPCT in group 1 were statistically significantly thinner than the control group (p<0.05). The mean CCT and TPCT in group 2 and group 3 were not statistically significantly different from the control group (p=1.000). Conclusion: In our study it was found that, the central and peripheral corneal thicknesses were thinner in seronegative RA patients when compared to seropositive RA and seronegative AS patients. The RF which has an important role in the extraarticular involvement was not found to be associated with the corneal thickness.

Özet

Amaç: Bu çalışmanın amacı seronegatif (romatoid faktör (RF) negatif) ve seropozitif (RF pozitif) romatolojik hastalıklarda santral ve periferik kornea kalınlığının ön segment optik koherans tomografisi (OKT) ile değerlendirilmesi ve bu hastalıklarda kornea kalınlığına RF’in etkisinin araştırılmasıdır. Gereç ve Yöntem: Seronegatif romatoid artrit (RA) olan 33 hastanın 66 gözü (grup 1), seropozitif RA olan 25 hastanın 50 gözü (grup 2) ve seronegatif ankilozan spondilitli (AS) 26 hastanın 52 gözü (grup 3) çalışma kapsamına alındı. Otuz sağlıklı bireyin 60 gözü de kontrol grubu olarak değerlendirildi. Bütün olgulara ön segment OKT ile santral kornea kalınlığı (SKK) ve temporalden periferik kornea kalınlığı (TPKK) ölçümü yapıldı. Sonuçlar gruplar arasında karşılaştırıldı. Bulgular: Yaş ortalaması grup 1’de 56,30±7,9 yıl, grup 2’de 53,66±9,22 yıl, grup 3’te 43,73±10,86 yıl, kontrol grubunda 51±7,82 yıl idi. Grup 1’de ortalama SKK 518,53 ±31,61μm, ortalama TPKK 704,87 ±46,81 μm idi. Grup 2’de ortalama SKK 536,33±35,12μm iken, ortalama TPKK 723,47±54,57 μm idi. Grup 3’te ortalama SKK 539,52±28,14 μm, ortalama TPKK 742,46±44,45 μm olarak ölçüldü. Kontrol grubunda ise ortalama SKK ve TPKK sırasıyla 540,59±38,94μm ve 740,64±42,28 μm bulundu. Grup 1’de ortalama SKK ve TPKK’ nın kontrol grubuna göre daha ince olması istatistiksel olarak anlamlı idi (p<0,05). Grup 2 ve grup 3’te ortalama SKK ve TPKK ölçümleri kontrol grubuyla karşılaştırıldığında ise istatistiksel olarak anlamlı bulunmadı (p=1,000). Sonuç: Çalışmamızda seronegatif RA hastalarında santral ve periferik kornea kalınlığı, seropozitif RA ve seronegatif AS hastalarına göre daha ince bulundu. Eklem dışı tutulumda önemli bir yere sahip olan RF’nin kornea kalınlığı ile ilişkisi bulunamadı.

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Cite This Article

YILDIZ, Y. T., SARAÇ, Ö., GÜRDAL, C., ERTEN, Ş., BAYRAKTAR, S. (2012). Central and peripheric corneal thicknesses in seronegative and seropositive rheumatologic diseases. MN Oftalmoloji, Cilt: 19 - Sayı: 3, 137–142. https://ajindex.com/articles/295767

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References (15)

  1. O’Dell JR. Rheumatoid arthritis: The clinical Picture. In Koopman WJ. Arthritis and Allied Conditions. Philadelphia: Lippincott Williams & Wilkins 2001:1157-86 2. Grassi W, De Angelis R, Lamanna G, Cervini C. The clinical features of rheumatoid arthritis. Eur J Radiol 1998
  2. Bacon AP, Moots JR. Extra-articular rheumatoid arthritis. In: Koopman JW, ed. Arthritis and Allied Conditions. A Textbook of Rheumatology. Baltimore: Williams and Wilkins 1997: 1071-88. 4. Minaur NJ, Jacoby RK, Cosh JA, et al. Outcome after 40 years with rheumatoid arthritis: a prospective study of function, disease activity and mortality. J Rheumatol 2004
  3. Kelley WN. Philadelphia W.B.Saundes. Textbook of rheumatology. 1985
  4. 511 6. Lindqvist E, Eberhardt K, Bendtzen K, Heinegard D, Saxne T. Prognostic laboratory markers of joint damage in rheumatoid arthritis. Ann Rheum Dis 2005
  5. Dahnert W. Radiology review manual. 4th ed. Baltimore: Williams & Wilkins 1999
  6. Van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum. 1984
  7. 8 9. Monnet D, Breban M, Hudry C, Dougados M, Brezin AP. Ophthalmic findings and frequency of extraocular manifestations in patients with HLA-B27 uveitis: a study of 175 cases. Ophthalmology 2004
  8. Pato E, Banares A, Jover JA et al. Undiagnosed spondyloarthropathy in patients presenting with anterior uveitis. J Rheumatol 2000
  9. Papadia M, Sofianos C, Iester M, Bricola G, Corneal thickness and visual field damage in glaucoma patients. Eye 2006
  10. Wolfs RCW, Klaver CCW, Vingerling JR. Distribution of central corneal thickness and its association with intraocular pressure: The Rotterdam Study. Am J Ophthalmol 1997
  11. 72 13. Foster PJ. Central corneal thickness and intraocular pressure in a Mongolian population. Ophthalmology 1998
  12. Aletaha D, Neogi T, Silman A et al. The 2010 American College of Rheumatology/European League Against Rheu - ma tism Classification Criteria for Rheumatoid Arthritis. Arthritis Rheum 2010
  13. Fujita M, Igarashi T, Kurai T, Sakane M, Yoshino S, Takahashi H. Correlation between dry eye and rheumatoid arthritis activity. Am J Ophthalmol 2005
  14. Harper SL, Foster CS. The ocular manifestations of rheumatoid disease. Int Ophthalmol Clin 1998
  15. Mc Gavin DDM, Williamson J, Forrester JB. Episcl