Journals / Molecular Imaging and Radionuclide Therapy / 2012 / Cilt: 21 - Sayı: 1

Takayasu arteriti tanılı hastanin tedavi öncesi ve sonrası F-18 FDG PET/BT bulguları

F-18 Fdg PET/CT findings of a patient with takayasu arteritis before and after therapy

Pages
32–34
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

FDG PET/CT is a sensitive technique for assessing presence of large-vessel vasculitis such as Takayasu arteritis, extent of large-vessel inflammation and disease activity after therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:Vasculitis is defined as inflammation and necrosis with leukocytic infiltration of the blood vessel wall.
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Key Findings & Data:A 64-year-old female patient with a 2-month history of fever of unknown origin was presented to our clinic for F-18 FDG PET/CT imaging.
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Conclusion & Impact:FDG PET/CT is a sensitive technique for assessing presence of large-vessel vasculitis such as Takayasu arteritis, extent of large-vessel inflammation and disease activity after therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Vasculitis is defined as inflammation and necrosis with leukocytic infiltration of the blood vessel wall. Takayasu arteritis is a chronic inflammatory arteritis that primarily involves the aorta and its main branches. A 64-year-old female patient with a 2-month history of fever of unknown origin was presented to our clinic for F-18 FDG PET/CT imaging. Baseline PET/CT images demonstrated intense F-18 FDG uptake in the aorta, bilateral subclavian and brachiocephalic arteries consistent with Takayasu arteritis. After 2 months of immunosuppressive therapy, she was asymptomatic and follow-up FDG PET/CT scan showed almost complete disappearance of large vessels’ F-18 FDG uptake. FDG PET/CT is a sensitive technique for assessing presence of large-vessel vasculitis such as Takayasu arteritis, extent of large-vessel inflammation and disease activity after therapy.

Özet

Vaskülit, kan damarı duvarının lökosit infiltrasyonuyla birlikte inflamasyon ve nekrozu olarak tanımlanır. Takayasu arteriti kronik inflamatuar arterit olup, genellikle aorta ve ana dallarını tutar. İki aydır nedeni bilinmeyen ateş hikâyesi olan 64 yaşında kadın hasta kliniğimize F-18 FDG PET/BT çekimi için başvurdu. İlk yapılan PET/BT çalışmasında aorta, her iki subklavyen arterler ve brakiosefalik arterlerde Takayasu arteriti ile uyumlu, yoğun F-18 FDG tutulumları görüldü. 2 ay immunsupresif tedavi sonrasında hasta asemptomatik olup, tekrar PET/BT çalışmasında büyük damarlarda izlenen F-18 FDG tutulumları tama yakın oranda kayboldu. F-18 FDG PET/BT ile görüntüleme, Takayasu arteriti gibi büyük damarlarda görülen vaskülit tanısında, inflamasyon yaygınlığının ve tedavi sonrası hastalık aktivitesinin değerlendirilmesinde duyarlı bir yöntemdir.

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Cite This Article

SAĞER, M. S., YILMAZ, S., ÖZHAN, M., HALAÇ, M., ERGÜL, N., ÇİFTÇİ, H., ÇERMİK, T. F. (2012). Takayasu arteriti tanılı hastanin tedavi öncesi ve sonrası F-18 FDG PET/BT bulguları. Molecular Imaging and Radionuclide Therapy, Cilt: 21 - Sayı: 1, 32–34. https://ajindex.com/articles/295196

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