A case of schizophrenia accompanying velocardiofacial syndrome

Objective & Hypothesis:Velocardiofacial syndrome (VCFS), the most frequent microdeletion syndrome identified in humans, is associated with chromosomal microdeletions in the q11 band of chromosome 22.

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Key Findings & Data:Individuals with VCFS are reported to have a characteristic behavioral phenotype with high rates of behavioral, psychiatric, neuropsychological and linguistic disorders.

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Conclusion & Impact:This article aimed to present a case of VCFS with schizophrenia.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Genç erişkin · DiGeorge sendromu · Şizofreni

Abstract

Velocardiofacial syndrome (VCFS), the most frequent microdeletion syndrome identified in humans, is associated with chromosomal microdeletions in the q11 band of chromosome 22. Individuals with VCFS are reported to have a characteristic behavioral phenotype with high rates of behavioral, psychiatric, neuropsychological and linguistic disorders. It was noted that patients with VCFS have a higher prevalence of schizophrenia, mood disorders and attention deficit hyperactivity disorder. This article aimed to present a case of VCFS with schizophrenia.

Özet

Velokardiyofasiyal sendrom (VKFS) 22. kromozomun q11 bandında gözlenen mikrodelesyonların eşlik ettiği, insanlarda görülen en yaygın mikrodelesyon sendromudur. VKFS hastalarının davranışsal, psikiyatrik, nöropsikolojik ve lisan bozukluklarının gözlendiği karakteristik bir davranışsal fenotipleri vardır. Çalışmalarda, VKFS hastalarında şizofreni, duygudurum bozuklukları ve dikkat eksikliği hiperaktivite bozukluğu sıklığının artmış olduğuna dikkat çekilmektedir. Bu yazıda, VKFS’un eşlik ettiği bir şizofreni tablosunun sunulması amaçlanmıştır.

Keywords

Genç erişkin DiGeorge sendromu Şizofreni Kadın İn situ hibridizasyon floresan Genetik Young Adult DiGeorge Syndrome Schizophrenia Female In Situ Hybridization Fluorescence Genetics

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Cite This Article

ŞENGÜL, C., EFE, M., TEPELİ, E., ÇETİN, G. O., DÜZCAN, F., HERKEN, H. (2009). A case of schizophrenia accompanying velocardiofacial syndrome. Nöropsikiyatri Arşivi, Cilt: 46 - Sayı: 1, 27–29. https://ajindex.com/articles/292897

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