Journals / Nöropsikiyatri Arşivi / 2009 / Cilt: 46 - Sayı: 3

Neuropsychiatric findings in a delayed encephalopathy due to carbon monoxide intoxication

Karbonmonoksit zehirlenmesine bağlı bir geç ensefalopati olgusunda nöropsikiyatrik bulgular

Pages
121–124
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The differential diagnosis of the rich neuropsychiatric findings together with cranial magnetic resonance imaging findings (MRI) are discussed in this patient.

📌 3 Key Takeaways

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Objective & Hypothesis:Carbon monoxide (CO) intoxication can be a deadly condition and is a very common public health problem in Turkey due to the use of coal stoves during the winter months in homes.
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Key Findings & Data:In this case report, we present a 35-year-old man, who was admitted to the hospital because of irritability and loose mind.
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Conclusion & Impact:The differential diagnosis of the rich neuropsychiatric findings together with cranial magnetic resonance imaging findings (MRI) are discussed in this patient.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erişkin · Karbonmonoksit zehirlenmesi · Oksijen azlığı

Abstract

Carbon monoxide (CO) intoxication can be a deadly condition and is a very common public health problem in Turkey due to the use of coal stoves during the winter months in homes. Carbon monoxide intoxication accounts for more than half of the deaths due to intoxications in Turkey. It is very likely to misdiagnose the cases of delayed anoxic encephalopathy (DAE) which are seen after the latent period following the acute intoxication. In delayed anoxic encephalopathy, following complete recovery and after a latent period, neurologic and/or psychiatric symptoms appear again. The symptom triad of DAE is mental deterioration, urinary and/or gaita incontinence and gait disturbances. The psychiatric appearance in DAE can be seen in a variety of very different findings including dementia, amnestic syndromes, organic affective disorders, personality disorders and psychosis. In this case report, we present a 35-year-old man, who was admitted to the hospital because of irritability and loose mind. The patient did not have any previous psychiatric or neurologic disorder, but he had CO intoxication 33 days before the admission and was discharged from the hospital following a hyperbaric oxygen treatment with a complete recovery. After a 15-day latency period he was admitted to the hospital because of the mentioned symptoms. The differential diagnosis of the rich neuropsychiatric findings together with cranial magnetic resonance imaging findings (MRI) are discussed in this patient.

Özet

Karbon monoksit (CO) zehirlenmesi ölümcül seyredebilen ve ülkemizde özellikle kış aylarında kapalı ortamlarda yakılan kömür sobalarına bağlı olarak sık görülen bir halk sağlığı sorunudur. Ülkemizde zehirlenme nedeniyle ölümlerin yarısından fazlasında neden karbon monoksit zehirlenmesidir. Özellikle akut zehirlenmeyi takiben sessiz dönemden sonra ortaya çıkan geç anoksik ensefalopati (GAE) olgularında yanlış tanı alma olasılığı artmaktadır GAE’nin semptom üçlüsü mental durumda bozulma, idrar ve/veya gaita inkontinansı ve yürüyüş bozukluğudur. GAE’deki psikiyatrik görünüm; demans, amnestik sendromlar, organik affektif bozukluklar, kişilik bozuklukları ve psikozu da içeren çok farklı klinik bulgularla ortaya çıkmaktadır. Bu yazıda 35 yaşında, daha önce psikiyatrik ya da nörolojik bir hastalığı olmayan ancak 33 gün önce CO zehirlenmesi geçiren ve hiperbarik oksijen (HBO) tedavisi sonrasında tam düzelme halinde taburcu edildiği öğrenilen ve 15 günlük sessiz bir dönemi takiben psikiyatri polikliniğine sinirlilik, unutkanlık şikayetleri nedeniyle başvuran bir erkek hasta sunulmuştur. Bu hastadaki nöropsikiyatrik bulguların ayırıcı tanısı, kraniyal manyetik rezonans görüntüleme (MRG) bulguları ile birlikte tartışılmıştır.

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Cite This Article

SARGIN, A. E., DÖNMEZ, H., ÖRSEL, S., YOLDAŞ, T. K. (2009). Neuropsychiatric findings in a delayed encephalopathy due to carbon monoxide intoxication. Nöropsikiyatri Arşivi, Cilt: 46 - Sayı: 3, 121–124. https://ajindex.com/articles/292745

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References (16)

  1. Karabacakoğlu A, Karaköse S, Deniz E ve ark. Akut karbon monoksit zehirlenmesinde kranyal MRG bulguları. Tanısal ve girişimsel radyoloji 2001; 7:488-93
  2. Werner B, Back W, Akerblom H et al. Two cases of acute carbon monoxide poisoning with delayed neurological sequelae after a “free” interval. J Toxicol Clin Toxicol 1985; 23:249-65
  3. Smallwood P, Murray GB. Neuropsychiatric aspects of carbon monoxide poisoning: A review and single case report suggesting a role for amphetamines. Ann Clin Psychiatry 1999; 11:21-7
  4. Min SK. A brain syndrome associated with delayed neuropsychiatric sequelae following acute carbon monoxide intoxication. Acta psychiatr. Scand. 1985; 73:80-6
  5. Choi IS. Delayed neurologic sequelae in carbon monoxide intoxication. Arch Neurol 1983; 40:433-5
  6. Kırel B, Akın A, Sezgin ME ve ark. Karbon monoksit zehirlenmesi ve hiperbarik oksijen tedavisi: Üç vaka takdimi. Çocuk sağlığı ve hastalıkları dergisi 2005; 48:164-7
  7. Choi IS. Carbon monoxide poisoning: systematic manifestations and complications. J Korean Med Sci 2001; 16:253-61
  8. Şenoğlu N, Öksüz H, Zencirci B et al. Parkinsonism after carbon monoxide ıntoxication: Case report. Journal of neurological sciences (Turkish) 2005; 22:292-6
  9. Ku BD, Shin HY, Kim EJ et al. Secondary mania in a patient with delayed anoxic encephalopathy after carbon monoxide intoxication. J Clin Neurosci 2005; 13:860-2
  10. Samuels AH, Vamos MJ, Taikato MR. Carbon monoxide, amnesia and hyperbaric oxygen therapy. Aust N Z J Psychiatry 1992; 26:316-9
  11. Hu MC, Shiah IS, Yeh CB et al. Ziprasidone in the treatment of delayed carbon monoxide encephalopathy. Prog Neuropsychopharmacol Biol Psychiatry 2006; 30:755-7
  12. Yüksel EG, Taşkın EO, Ovalı GY ve ark. Olgu sunumu: Karbon monoksit zehirlenmesi sonrasında ortaya çıkan kleptomani ve diğer psikiyatrik belirtiler. Turk Psikiyatri Derg 2007; 18:80-6
  13. Laplane D, Baulac M, Widlöcher D et al. Pure Psychic akinesia with bilateral lesions of basal ganglia. J Neurol Neurosurg Psychiatry 1984; 47:377-85
  14. Starkstein SE, Berthier ML, Leiguarda R. Psychic akinesia following bilateral pallidal lesions. Int J Psychiatry Med 1989; 19:155-64
  15. Lugaresi A, Montagna P, Morreale A et al. “Psychic Akinesia” following carbon monoxide poisoning. Eur Neurol 1990; 30:167-9
  16. Bogousslavsky J, Regli F, Delaloye B et al. Loss of psychic self-activation with bithalamic infarction neurobehavioural, CT, MRI and SPECT correlates. Acta Neurol Scand 1991; 83:309-16.