Journals / Nöropsikiyatri Arşivi / 2015 / Cilt: 52 - Sayı: 1

Geçici Global Amnezi'ye Neden Olan Vasküler İskemi: Hasta Serisi

Vascular Ischemia as a Cause of Transient Global Amnesia: A Patient Series

Pages
59–63
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Evaluations such as DWI and vascular risk factor assessment may be helpful in making the diagnosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Epileptic, migrainous, and vascular pathologies may cause transient global amnesia (TGA); however, the mechanism of causation remains unclear.
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Key Findings & Data:We investigated possible vascular causes of TGA.Methods: We retrospectively evaluated the clinical and radiologic studies of 13 patients with TGA.
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Conclusion & Impact:Evaluations such as DWI and vascular risk factor assessment may be helpful in making the diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Epileptic, migrainous, and vascular pathologies may cause transient global amnesia (TGA); however, the mechanism of causation remains unclear. We investigated possible vascular causes of TGA.Methods: We retrospectively evaluated the clinical and radiologic studies of 13 patients with TGA. On admission, patients underwent diffusionweighted imaging (DWI) and intra- and extracranial magnetic resonance angiography (MRA); vascular risk factor profiles for diabetes, hypertension, and hyperlipidemia; electroencephalography; and neuropsychological tests. Seven patients underwent control DWIs 24 h after symptom onset.Results: One patient had two punctiform acute infarcts in the left hippocampus, and one had a left pontine paramedian acute infarct. In the second patient, control DWI showed additional left hippocampal and right frontal acute infarcts. None of the patients had electroencephalographic evidence of epileptic activity. All patients except for one had at least one vascular risk factor. The second patient was shown to have paroxsysmal atrial fibrillation during follow-up.Conclusion: Minor posterior circulation ischemic stroke appears to cause TGA in some patients. Evaluations such as DWI and vascular risk factor assessment may be helpful in making the diagnosis.

Özet

Amaç: Geçici global amnezi (GGA) etyolojisinde, mekanizmaları tam bilinmemekle beraber epileptik, migrenöz ve vasküler patolojilerin sorumlu olabileceği düşünülmektedir. Bu çalışmamızda, GGA'nın vasküler nedenlerini araştırmayı amaçladık. Yöntem: GGA anamnezi ile başvuran 13 hastanın klinik ve radyolojik bil-gileri retrospektif olarak değerlendirildi. Hastaların difüzyon MR, intra ve ekstrakranyal MRanjiografi incelemeleri, vasküler risk faktörlerine yönelik tetkikleri, elektroensefalografi ve nöropsikolojik testleri yapıldı. Yedi has-tanın semptomların başlangıcından 24 saat sonra kontrol difüzyon MR incelemesi yapıldı.Bulgular: Bir hastada sol hipokampusta iki adet punktiform akut infarkt saptanırken bir hastada da sol pontin paramedyan infarkt izlendi. İkinci hastanın kontrol difüzyon MR incelemesinde, pontin paramedyan infarkta ek olarak sol hipokampal ve sağ frontal akut infarkt saptandı. Elektroen-sefalografik incelemelerde hiç bir hastada epileptik aktivite izlenmedi. Bir hasta dışında tüm hastalarda en az 1 vasküler risk faktörü saptandı. Akut infarkt saptanan ikinci hastada klinik takipler sırasında paroksismal atrial fibrilasyon tespit edildi.Sonuç: Posterior sirkülasyon minor inmeleri bazı hastalarda GGA nedeni olabilir. Bu hastalarda difüzyon MR incelemesi ve vasküler risk faktörlerini değerlendirmek tanı ve tedavide yardımcı olabilir.

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Cite This Article

TUNÇER, Ö. G., KOYUNCU, B. A., OKUDAN, Z. V., ALTINDAĞ, E., TOLUN, R., KRESPİ, Y. (2015). Geçici Global Amnezi'ye Neden Olan Vasküler İskemi: Hasta Serisi. Nöropsikiyatri Arşivi, Cilt: 52 - Sayı: 1, 59–63. https://ajindex.com/articles/292444

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