Journals / MANTAR DERGİSİ / 2018 / Cilt: 9 - Sayı: 2

Alkaloids from Mushrooms

Mantarlardan Elde Edilen Alkaloitler

Pages
117–125
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we focused on distribution and bioactivities of mushroom alkaloids.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Mushrooms (macrofungi) are a part of the human diet as a source of both food and medicine for centuries especially in East-Asia.
📊
Key Findings & Data:The use of mushrooms and their extracts for medicinal purposes became more popular due to increasing number of research conducting on them recently.
💡
Conclusion & Impact:In this review, we focused on distribution and bioactivities of mushroom alkaloids.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:makrofungus · alkaloit · Mycena

Abstract

Mushrooms (macrofungi) are a part of the human diet as a source of both food and medicine for centuries especially in East-Asia. The use of mushrooms and their extracts for medicinal purposes became more popular due to increasing number of research conducting on them recently. They predominantly contain polysaccharides, terpenes and sterols. Alkaloids exhibits bioactive effects even in very small doses and mainly distributed in Angiosperms. Their occurrences in macrofungi is very limited and not very-well documented as much as other constituents like polysaccharides or terpenes. In this review, we focused on distribution and bioactivities of mushroom alkaloids.

Özet

Mantarlar (makrofunguslar) besin kaynağı ve ilaç olarak özellikle Doğu Asya’da yüzyıllardır diyetin bir parçasıdır. Son zamanlarda üzerlerinde yapılan çalışmaların sayısının artması nedeniyle mantarların ve ekstrelerinin tıbbi amaçla kullanımı daha popüler hale gelmiştir. Mantarlar çoğunlukla polisakkaritler, terpenler ve steroller taşımaktadır. Alkaloitler çok düşük dozlarda bile biyoaktif etki gösterirler ve genellikle Angiospermlerde bulunurlar. Bu grup bileşiklerin makrofunguslarda bulunuşları oldukça sınırlıdır ve haklarında polisakkaritler ya da terpenler gibi diğer bileşiklerin mantarlarda yayılışları kadar detaylı bilgi yoktur. Bu derlemede, mantarlarda bulunan alkaloitlerin dağılımı ve biyoaktivitelerine odaklandık.

🔖

Cite This Article

FENDOĞLU, B., UZ, K. A., ŞÖHRETOĞLU, D. (2018). Alkaloids from Mushrooms. MANTAR DERGİSİ, Cilt: 9 - Sayı: 2, 117–125. https://ajindex.com/articles/279304

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Anke, T., Oberwinkler, F., Steglich, W., Schramm, G.J. The Strobilurins -New Antifungal Antibıotics From The Basidiomycete Strobilurus tenacellus (Pers. Ex Fr.) Sing, Antibiotics, 30(10)806−810(1977).
  2. Antunes, E. M., Copp, B.R., Davies-Coleman, M.T., Samaai, T., Pyrroloiminoquinone and related metabolites from marine sponges, Nat. Prod. Rep., 22(1)62-72(2005).
  3. Barros-Fihlo, B.A., de Oliveira, M.C., Mafezoli, J.; Barbosa, F.G., Rodrigues-Filho, E., Secondary metabolite production by the basidiomycete, Lentinus strigellus, under different culture conditions, Nat. Prod. Commun., 7(6)771−773(2012).
  4. Bogenschutz, M.P., Forcehimes, A.A., Pommy, J.A., Wilcox, C.E., Barbosa, P.C., Strassman, R.J., Psilocybin-assisted treatment for alcohol dependence: a proof-of-concept study, J Psychopharmacol, 29(3)289-299(2015).
  5. Bogenschutz M.P., Ross S., Therapeutic Applications of Classic Hallucinogens, Curr Top Behav Neurosci, (2017). doi: 10.1007/7854_2016_464. Carod-Artal, F.J., Hallucinogenic drugs in pre-Columbian Mesoamerican cultures, Neurologia, 30(1)42-9(2015).
  6. Chiu, C.H., Chyau, C.C., Chen, C.C., Lee, L.Y., Chen, W.P., Liu, J.L., Lin, W.H., Mong, M.C., Erinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice, Int. J. Mol. Sci., 19(2)341(2018).
  7. Dewick, P.M., Medicinal Natural Products: A Biosynthetic Approach, John Wiley & Sons Ltd., West Sussex(2002).
  8. Eyal, Z., Matzov, D., Krupkin, M., Paukner S., Riedl R., Rozenberg H., Zimmerman E., Bashan A., Yonath A., A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism, Sci. Rep., 6,1−8(2016).
  9. Griffiths, R.R., Johnson, M.W., Carducci, M.A., Umbricht, A., Richards, W.A., Richards, B.D., Cosimano, M.P., Klinedinst, M.A., Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial, J. Psychopharmacol, 30(12)1181-1197(2016).
  10. Grob, C.S., Danforth, A.L., Chopra, G.S., Hagerty, M., McKay, C.R., Halberstadt, A.L., Greer, G.R., Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer, Arch Gen Psychiatry., 68(1)71-78(2011).
  11. Heinrich, M., Barnes, J., Gibbons, S., Williamson, E., Fundamentals of Pharmacognosy and Phytotherapy, Second Ed., Elsevier, Livingstone(2012).
  12. Hellwig, V., Dasenbrock, J., Klostermeyer, D., Kroiß, S., Sindlinger, T., Spiteller, P., Steffan, B., Steglich, W., Engler-Lohr, M