As authors, in the light of cases we report and literature knowledge, we think that children with PFAPA syndrome could be under risk in terms of psychiatric problems due to common inflammatory etiology.
📌 3 Key Takeaways
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Objective & Hypothesis:PFAPA syndrome is an auto inflammatory disease.
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Key Findings & Data:Researchers have stated that auto inflammatory mechanisms can play a role in etiology of several psychiatric diseases and for this reason auto inflammatory diseases are frequently associated with psychiatric disorders.
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Conclusion & Impact:As authors, in the light of cases we report and literature knowledge, we think that children with PFAPA syndrome could be under risk in terms of psychiatric problems due to common inflammatory etiology.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
PFAPA syndrome is an auto inflammatory disease. Researchers have stated that auto inflammatory mechanisms can play a role in etiology of several psychiatric diseases and for this reason auto inflammatory diseases are frequently associated with psychiatric disorders. The purpose of this paper, it is aimed to report two cases diagnosed with PFAPA syndrome and having psychiatric symptoms and to discuss them accompanied by literature data. As authors, in the light of cases we report and literature knowledge, we think that children with PFAPA syndrome could be under risk in terms of psychiatric problems due to common inflammatory etiology.
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Cite This Article
DÖNMEZ, Y. E., ÖZCAN, Ö., TABEL, Y. (2019). Coexistence of PFAPA syndrome with separation anxiety. Medicine Science, Cilt: 8 - Sayı: 1, 247–249. https://ajindex.com/articles/277133
Thomas KT, Feder HM, Lawton AR, et al. Periodic fever syndrome in children. J Pediatr. 1999;135:15-21.
Brown KL, Wekell P, Osla V, et al. Profile of blood cells and inflammatory mediators in periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome. BMC Pediatr. 2010;10:65. Mitchell RH, Goldstein BI. Inflammation in children and adolescents with neuropsychiatric disorders: a systematic review. J Am Acad Child Adolesc Psychiatry. 2014;53:274-96.
Marshall GS, Edwards KM, Butler J, et al. Syndrome of periodic fever, pharyngitis, and aphthous stomatitis. J Pediatr. 1987;110:43-6.
Vigo G, Zulian F. Periodic fevers with aphthous stomatitis, pharyngitis, and adenitis (PFAPA). Autoimmun Rev. 2012;12:52-5.
Henje BE, Lekander M, Ingvar M, et al. Proinflammatory cytokines are elevated in adolescent females with emotional disorders not treated with SSRIs. J Affect Disord. 2012;136:716-23.