SavedAdd your journal

Journals / KSÜ Tıp Fakültesi Dergisi / 2005 / Cilt: 2 - Sayı: 2

The epidemiology of Basal cell carcinoma

Bazal hücreli kanser epidemiyolojisi

Sezai ŞAŞMAZ
Pages
53–56
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Research in free radical-mediated cellular injury and innate defense mechanisms and ultraviolet radiation-induced genetic mutations have improved our understanding of the development of this disorder.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Basal cell carcinoma is the most common malignancy among white populations.
📊
Key Findings & Data:Over the past twenty years, significant increases in the incidence of basal cell carcinoma have been observed.
💡
Conclusion & Impact:Research in free radical-mediated cellular injury and innate defense mechanisms and ultraviolet radiation-induced genetic mutations have improved our understanding of the development of this disorder.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Epidemiyolojik faktörler · Karsinom · bazal hücreli

Abstract

Basal cell carcinoma is the most common malignancy among white populations. Over the past twenty years, significant increases in the incidence of basal cell carcinoma have been observed. The incidence of basal cell carcinoma rises with age, but the disease is becoming more common in younger adults. Risk factors include fair skin, prior skin cancers, immunosuppression and a history of sunburn in childhood and adolescence. Research in free radical-mediated cellular injury and innate defense mechanisms and ultraviolet radiation-induced genetic mutations have improved our understanding of the development of this disorder.

Özet

Bazal hücreli kanser beyaz toplumda en sık görülen habis tümördür. Son yirmi yıllık dönemde insidansında belirgin bir artış gözlenmektedir. İnsidansı yaşla artmakla birlikte genç erişkinlerde giderek daha yaygınlaşmaktadır. Risk faktörleri açık tenlilik, geçirilmiş deri kanseri, immünsüpresyon ve çocukluk ile adolesan dönemde güneş yanıkları öyküsünü içerir. Serbest radikal ilişkili hücresel hasar, doğal savunma mekanizmaları ve ultraviyolenin neden olduğu genetik mutasyonlarla ilgili araştırmalar bazal hücreli kanserle ilgili bildiklerimizi ilerletmiştir.

🔖

Cite This Article

ŞAŞMAZ, S. (2005). The epidemiology of Basal cell carcinoma. KSÜ Tıp Fakültesi Dergisi, Cilt: 2 - Sayı: 2, 53–56. https://ajindex.com/articles/274546

References (1)

  1. Wong CSM, Strange RC, Lear JT. Basal cell carcinoma. BMJ 2003;327:794-8. 2.Tran H, Chen K, Shumack S. Epidemiology and aetiology of basal cell carcinoma. Br J Dermatol 2003;149(Suppl. 66):50-2. 3.Stern RS. The mysteries of geographic variability in nonmelanoma skin cancer incidence. Arch Dermatol 1999;135:843-4. 4.Seçkin D. Bazal hücreli epitelyomanın etyopatogenezi. T Klin Dermatoloji 2002; 12(Suppl.): 185-7. 5.Carucci JA, Leffell DJ. Basal cell carcinoma. In: Friedberg IM, Eisen AZ, Wolff K et al.(eds). Dermatology in General Medicine. McGraw-Hill, 2003:747-54. 6.Şendur N. Bazal hücreli epitelyoma. Epidemiyoloji. T Klin Dermatoloji 2002;12(Suppl.):181-4. 7.de Vries E, Louwman M, Bastiaens M, de Gruij1 F, Coebergh JW. Rapid and continuous increases in incidence rates of basal cell carcinoma in the southeast Netherlands since 1973. J Invest Dermatol 2004;123:634-8. 8.TC Sağlık Bakanlığı Kanser İstatistikleri. URL: (Erişim: 12 Kasım 2004). 9.Şaşmaz S, Çelik M, Ekerbiçer HÇ, Çetinkaya A. Yaşlılarda deri hastalıkları. Geriatri 2003;6:51-4. 10.Odom RB, James WD, Berger TG: Andrews' Diseases of the Skin. Philadelphia, W.B. Saunders Company. 2000:825. 11.Habif TP. Clinical Dermatology. Chapter 21, 4th ed. Mosby, 2004, URL: /das/book/view/ 38702448-2/1195/163.html/top (Erişim: 12 Kasım 2004). 12.Miller SJ, Moresi JM. Actinic keratosis, basal cell carcinoma and squamous cell carcinoma. In: Bolognia JL, Jorizzo JL, Rapini RP et al. (eds). Dermatology. Mosby, 2003:1677-96. 13.Ponten F, Lundeberg J. Principles of tumor biology and pathogenesis of BCCs and SCCs. In: Bolognia JL, Jorizzo JL, Rapini RP et al. (eds). Dermatology. Barcelona: Mosby, 2003:1663-76. 14.Oram Y, Orengo I, Griego RD, Rosen T, Thornby J. Histologic patterns of basal cell carcinoma based upon patient immunostatus. Dermatol Surg 1995;21:611-4. 15.Oram Y, Goldberg LH, Kolbusz RV. Basal cell carcinoma developing within a smallpox vaccination scar. T Klin Dermatoloji 1993;3:139-41. 16.Aydın N, Gül Ü. Nonmelanoma deri kanser­lerinin epidemiyolojisi. XX. Ulusal Dermatoloji Kongresi Bildiri Kitabı 2004:88 (P59). 17.Taipale J, Chen JK, Cooper MK et al. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature 2000;406:1005-9.