Journals / İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi / 2013 / Cilt: 3 - Sayı: 1

Rebound compulsive behaviors upon abrupt discontinuation of valproate in a child with autistic disorder

Otistik çocuk hastada valproatın ani kesilmesine bağlı rebound kompulsif davranışlar

Pages
71–74
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the management of ASD cases, especially for the drug treatment, family education and close follow up are of vital importance.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Compulsive behaviors are commonly encountered in children and adolescents with Autistic Spectrum Disorders (ASD).
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Key Findings & Data:In this case report, the abrupt discontinuation of valproate by family, which has been used for the treatment of epilepsy, in an 16-year-old girl with autistic disorder will be presented.
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Conclusion & Impact:In the management of ASD cases, especially for the drug treatment, family education and close follow up are of vital importance.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Compulsive behaviors are commonly encountered in children and adolescents with Autistic Spectrum Disorders (ASD). Psychotopic drugs are shown to be effective in the treatment of compulsive behaviors, stereotypical movements and aggressive symptoms. Valproate is usually used for the comorbid epilepsy in ASD. The role and efficacy of valproate in the psychiatric treatment of ASD, however, have been shown in a limited number of studies. In this case report, the abrupt discontinuation of valproate by family, which has been used for the treatment of epilepsy, in an 16-year-old girl with autistic disorder will be presented. In this case, rebound compulsive behaviors emer- ged with the discontinuation of valproate and symptoms disappeared with the restar- ting of the drug. In the management of ASD cases, especially for the drug treatment, family education and close follow up are of vital importance.

Özet

Otistik spektrum bozukluklar (OSB) tanılı çocuk ve ergenlerde kompulsif davranışla- ra sık olarak rastlanmaktadır. Psikotrop ilaçların OSB’ye eşlik eden kompulsif dav- ranışlar, stereotipik hareketler ve agresyon belirtilerine yararlı olabildiği gösterilmiş- tir. OSB’de eşlik eden epilepsi nedeniyle valproat sıklıkla kullanılmaktadır. OSB’de psikiyatrik tedavide valproatın yeri ve etkinliği ise sınırlı sayıda klinik çalışmada gösterilmiştir. Bu olgu sunumunda 16 yaşında OSB tanılı bir kız hastada epilepsi tedavisi için kullanılan valproatın aile tarafından ani olarak kesilmesi ile gelişen kli- nik tablo anlatılmıştır. Olguda valproatın kesilmesine bağlı rebound kompulsif davra- nışlar gelişmiş ve ilacın yeniden başlanması ile belirtilerin düzeldiği görülmüştür. OSB tanılı olgulara yaklaşımda, özellikle yürütülen ilaç tedavilerinde, ailelerin iyi bilgilen- dirilmesi ve yakın takip büyük önem taşımaktadır.

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Cite This Article

EKİNCİ, Ö., ÇELİK, T., TOROS, F. (2013). Rebound compulsive behaviors upon abrupt discontinuation of valproate in a child with autistic disorder. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, Cilt: 3 - Sayı: 1, 71–74. https://ajindex.com/articles/268751

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