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Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2017 / Cilt: 27 - Sayı: 2

Role of diffusion-weighted MR imaging in solid breast masses and complicated cysts

Solid meme kitleleri ve komplike kistlerde diffüzyon ağırlıklı manyetik rezonans görüntülemenin yeri Semiha CanveRenleR1, Zehra Hilal adıbellı2, emre CanveRenleR3, Özgür Sipahi eSen2, İbrahim ataSoy4, baha Zengel5

Semiha CANVERENLER
Pages
93–102
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

DWI is effective in detecting breast lesions and also ADC value is useful in distinguishing among complicated cysts/abscesses, malignant and benign breast lesions.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The purpose of this study is to evaluate the characteristics of malign/benign lesions and complicated cysts/abscesses in diffusion weighted magnetic resonance imaging and to investigate the contribution of apparent diffusion coefficient (ADC) to differential diagnosis.
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Key Findings & Data:Methods: In this retrospective study; histopathologically proven 177 lesions (21 complicated cysts, 91 malign and 65 bening lesions) were evaluated in 116 women using conventional MRI and diffusion weighted imaging (DWI).Results: Mean ADC values obtained in our study were 0.88±0.3x10-3 cm2/sec for 91 malignant, and 1.52±0.3x10-3 cm2/sec for 65 benign lesions, 0.55±0.3x10-3 cm2/sec for 21 complicated cysts/abscesses and and a statistically significant difference was detected among mean lesion ADC values (P<0.001).
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Conclusion & Impact:DWI is effective in detecting breast lesions and also ADC value is useful in distinguishing among complicated cysts/abscesses, malignant and benign breast lesions.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The purpose of this study is to evaluate the characteristics of malign/benign lesions and complicated cysts/abscesses in diffusion weighted magnetic resonance imaging and to investigate the contribution of apparent diffusion coefficient (ADC) to differential diagnosis. Methods: In this retrospective study; histopathologically proven 177 lesions (21 complicated cysts, 91 malign and 65 bening lesions) were evaluated in 116 women using conventional MRI and diffusion weighted imaging (DWI).Results: Mean ADC values obtained in our study were 0.88±0.3x10-3 cm2/sec for 91 malignant, and 1.52±0.3x10-3 cm2/sec for 65 benign lesions, 0.55±0.3x10-3 cm2/sec for 21 complicated cysts/abscesses and and a statistically significant difference was detected among mean lesion ADC values (P<0.001). We calculated threshold ADC values to discriminate between malignant and benign lesions, and between these lesions and complicated cysts/abscesses as 1.1x10-3 cm2/sec (P<0.001), and 0.6x10-3 cm2/sec (P<0.001), respectively. The ADC values identified for complicated cysts/abscesses are significantly lower than the ADC values of benign and malign values reported in the literature. Conclusion: As a result, the specificity, positive predictive value and negative predictive value of DWI when it is used alone are higher than conventional MRI, while sensitivity of DWI is nearly the same. DWI is effective in detecting breast lesions and also ADC value is useful in distinguishing among complicated cysts/abscesses, malignant and benign breast lesions.

Özet

Amaç: Çalışmamızın amacı, memede diffüzyon ağırlıklı manyetik resonans (MR) görüntüleme ile komplike kist-apse, benign ve malign lezyonların özelliklerinin değerlendirilmesi ve bu lezyonların açık diffüzyon katsayısının (apparent diffusion coefficient-ADC) belirlenmesidir.Yöntem: Bu retrospektif çalışmada, 116 kadın hastaya ait histopatholojik tanısı olan 21 komplike kist, 91 malign ve 65 benign toplam 177 lezyon konvansiyonel MR ve diffüzyon ağırlıklı MR görüntüleme ile değerlendirildi.Bulgular: Çalışmamızda, saptanan ortalama ADC değeri 91 malign lezyonda 0,88±0,3x10-3 cm2/sn, 65 benign lezyonda 1,52±0,3x10-3 cm2/sn, 21 komplike kiste 0,55±0,3x10-3 m2/sn olup, ortalama ADC değerleri arasındaki fark istatistiksel olarak anlamlıdır (P<0,001). Malign ve benign lezyonların komplike kistlerden ayrımında eşik değer 0,6x10-3 cm2/sn (P<0,001), malign ve benign lezyonların birbirinden ayrımında eşik değer 1,1x10-3 cm2/sn (P<0,001) olarak tespit edilmiştir. Komplike kist ve abselerin ADC değerleri malign ve benign lezyonların ADC değerlerinden istatistiksel olarak anlamlı derecede düşüktür.Sonuç: Sonuç olarak, tek başına diffüzyon MR kullanıldığında, saptanan özgüllük, pozitif ve negatif öngürü değerleri konvansiyonel MR incelemeye göre yüksek, duyarlılık ise çok Alındığı tarih: 29.09.2016 yakın değerdedir. Diffüzyon MR inceleme meme lezyonlarının etkin olup, ADC değerleri lezyonların benign, malign ve komplike kist ayrımında kullanılabilir.

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Cite This Article

CANVERENLER, S. (2017). Role of diffusion-weighted MR imaging in solid breast masses and complicated cysts. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 27 - Sayı: 2, 93–102. https://ajindex.com/articles/268365

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