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Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2014 / Cilt: 24 - Sayı: 2

DIAGNOSTIC VALUE OF PROTON MR SPECTROSCOPY IN BRAIN TUMORS

PROTON MR SPEKTROSKOPİNİN BEYİN TÜMÖRLERİNDE TANISAL DEĞERİ

Özgür Sipahi ESEN
MEHMET BOZKURT
Zehra Hilal ADIBELLİ
Eda AYKUT
Semiha CANVERENLER
Pages
93–98
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We discuss the clinical impact of MR spectroscopy in diagnosis of tumours and their differentiation from non-neoplastic lesions

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Our objective was to evaluate the usefulness of proton magnetic resonance (MR) spectroscopy in diagnosis of brain tumors.
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Key Findings & Data:Materials And Methods: Proton MR spectroscopy was performed in 49 patient with brain tumors (12 low- grade astrocytomas, 7 anaplastic astrositomas, 6 glioblastomas, 13 meningiomas, 11 metastases).
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Conclusion & Impact:We discuss the clinical impact of MR spectroscopy in diagnosis of tumours and their differentiation from non-neoplastic lesions
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Our objective was to evaluate the usefulness of proton magnetic resonance (MR) spectroscopy in diagnosis of brain tumors. Materials And Methods: Proton MR spectroscopy was performed in 49 patient with brain tumors (12 low- grade astrocytomas, 7 anaplastic astrositomas, 6 glioblastomas, 13 meningiomas, 11 metastases). Proton MR spectroscopy was performed with a 1.5 T MR unit. Results: In patients with brain tumors, a decrease in N-acetyl aspartate (NAA) and an increase in choline (Cho) level were detected when compared with those in the spectra obtained from normal tissue. Non-neoplazic lesions such as cerebral infarctions and brain abscesses are marked by decrease in Cho , creatin (Cr) and NAA. Conclusıon: Proton MR may be complementary to conventional MR imaging and CT. We discuss the clinical impact of MR spectroscopy in diagnosis of tumours and their differentiation from non-neoplastic lesions

Özet

Amaç: Manyetik rezonans (MR) spektroskopinin beyin tümörlerinde tanı değerinin ortaya konulmasıdır. Gereç ve Yöntem: Beyin tümörü tanısı alan 49 olguda (12 düşük dereceli astrositom, 7 anaplastik astrositoma, 6 glioblastom, 13 meningiom,11 metastaz) MR spektroskopi uygulanmıştır. Proton MR spektroskopi, 1.5 Tesla MR cihazı kullanılarak yapılmıştır. Bulgular: Beyin tümörlü hastalarda normal beyin dokusu ile karşılaştırıldığında N-asetil aspartat azlığı (NAA) ve kolin yüksekliği saptanmıştır. Beyin infarktı ve beyin apsesi gibi neoplazik olmayan lezyonlarda ise kolin, kreatin ve NAA düzeylerinde azalma belirlenmiştir. Sonuç: Proton MR spektroskopi BT ve MR bulgularının spesifik olmadığı birçok olguda tanıyı kolaylaştıran, klasik MR'ın tamamlayıcısı olan ileri inceleme yöntemlerinden biridir. Bu çalışmada MR spektroskopinin beyin tümörünün tanısı ve neoplazik olmayan diğer lezyonlarda ayırıcı tanısında klinik önemi vurgulanmıştır

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Cite This Article

ESEN, Ö. S., BOZKURT, M., ADIBELLİ, Z. H., AYKUT, E., CANVERENLER, S. (2014). DIAGNOSTIC VALUE OF PROTON MR SPECTROSCOPY IN BRAIN TUMORS. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 24 - Sayı: 2, 93–98. https://ajindex.com/articles/268379

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