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Journals / Hacettepe Journal of Biology and Chemistry / 2020 / Cilt: 48 - Sayı: 2

Lectin Affinity Based Recognition Nanomaterial for Glucose

Kevser KUŞAT
Cansu KURU
Fulden ULUCAN
Sinan AKGÖL
Pages
179–190
Publication Date
2020-04-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Lectin affinity based nanopolymeric system that is selective, with high surface area, low cost and highly biocompatible with high adsorption capacity has been developed for recognition of glucose.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Glucose is an important biomolecule because it is an important source of energy for cells and is used as an intermediate/metabolic agent.
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Key Findings & Data:The best interaction of p(GMA)-ConA nanopolymer and glucose was determined to be 10mM glucose concentration at pH = 8.0.
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Conclusion & Impact:Lectin affinity based nanopolymeric system that is selective, with high surface area, low cost and highly biocompatible with high adsorption capacity has been developed for recognition of glucose.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Nanotechnology · Glucose · Lectin Affinity Chromatography

Abstract

Glucose is an important biomolecule because it is an important source of energy for cells and is used as an intermediate/metabolic agent. Selective recognition of glucose is important for diagnosing many metabolic diseases. In this study, lectin ligand (Con A) attached p(GMA) nanopolymer was synthesized and characterized. The best interaction of p(GMA)-ConA nanopolymer and glucose was determined to be 10mM glucose concentration at pH = 8.0. In the selectivity assay, p(GMA)-Con A was found to be 2-fold selective for glucose than galactose. Lectin affinity based nanopolymeric system that is selective, with high surface area, low cost and highly biocompatible with high adsorption capacity has been developed for recognition of glucose.

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Cite This Article

KUŞAT, K., KURU, C., ULUCAN, F., AKGÖL, S. (2020). Lectin Affinity Based Recognition Nanomaterial for Glucose. Hacettepe Journal of Biology and Chemistry, Cilt: 48 - Sayı: 2, 179–190. https://ajindex.com/articles/255759

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