Further the concerns for future direction regard to clinical phase transfer has been discussed.
📌 3 Key Takeaways
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Objective & Hypothesis:Electrospinning has received tremendous attention in the fabrication of nanofibrous scaffolds over recent years and employed in different biomedical applications because of their biomimetic nature.
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Key Findings & Data:Especially, the electrospun nanofibers exhibit several beneficial features including natural extracellular matrix (ECM), interconnected pores, large surface area, ease of functionalization and mechanical performance that holds huge importance in influencing the cell adhesion, differentiation and proliferation behaviour.
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Conclusion & Impact:Further the concerns for future direction regard to clinical phase transfer has been discussed.
Electrospinning has received tremendous attention in the fabrication of nanofibrous scaffolds over recent years and employed in different biomedical applications because of their biomimetic nature. Especially, the electrospun nanofibers exhibit several beneficial features including natural extracellular matrix (ECM), interconnected pores, large surface area, ease of functionalization and mechanical performance that holds huge importance in influencing the cell adhesion, differentiation and proliferation behaviour. To date, acknowledging the wide range of beneficial features, the electrospun nanofibers have been used in wound dressing and tissue engineering applications. This review summarizes various efforts have been made in these areas with several representative examples indicating use of various materials and approaches. Further the concerns for future direction regard to clinical phase transfer has been discussed.
BALUSAMY, B., SENTHAMİZHAN, A., UYAR, T. (2020). Electrospun Nanofibers for Wound Dressing and Tissue Engineering Applications. Hacettepe Journal of Biology and Chemistry, The 100 Year of Polymers, 459–481. https://ajindex.com/articles/255698
T. Lin, J. Fang, Fundamentals of electrospinning & electrospun nanofibers, DEStech Publications, Inc, Pennsylvania, USA, 2017
Z. Li, C. Wang, One-dimensional nanostructures: Electrospinning technique and unique nanofibers, Springer-Verlag, Berlin Heidelberg, Germany, 2013
B. Ding, X. Wang, J. Yu, Electrospinning: Nanofabrication and applications, William Andrew, Elsevier, Amsterdam, Netherland, 2019
G.R. Mitchell, Electrospinning: Principles, practice and possibilities, The Royal Society of Chemistry, Cambridge, UK, 2015
J.H. Wendorff, S. Agarwal, A. Greiner, Electrospinning: Materials, processing, and applications, Wiley, Weinheim, Germany, 2012
J. Xue, T. Wu, Y. Dai, Y. Xia, Electrospinning and electrospun nanofibers: Methods, materials, and applications, Chem. Rev., 119 (2019) 5298–5415
S. Mohammadzadehmoghadam, Y. Dong, S. Barbhuiya, L. Guo, D. Liu, R. Umer, X. Qi, Y, Tang, Electrospinning: Current status and future trends, In: S. Fakirov (eds), Nano-size polymers, Springer, Cham, Switzerland, 2016, pp. 89-154
F. Topuz, T. Uyar, Electrospinning of cyclodextrin functional nanofibers for drug delivery applications, Pharmaceutics, 11 (2019) 6
A.F. Ismail, N. Hilal, J. Jaafar, C. Wright, Nanofiber membranes for medical, environmental, and energy applications, CRC Press, Boca Raton, FL, USA 2019
B. Ding, J. Yu, Electrospun nanofibers for energy and environmental applications, Springer, Berlin/Heidelberg, Germany, 2014
G. Sun, L. Sun, H. Xie, J. Liu, Electrospinning of nanofibers for energy applications, Nanomaterials, 6 (2016), 129
H. Liu, C.R. Gough, Q. Deng, Z. Gu, F. Wang, X. Hu, Recent advances in electrospun sustainable composites for biomedical, environmental, energy, and packaging applications, Int. J. Mol. Sci., 21 (2020) 4019
Z. Tong, L. Huang, W. Lei, H. Zhang, S. Zhang, Carbon-containing electrospun nanofibers for lithium–sulfur battery: Current status and future directions, J. Energy Chem., 54 (2021), 254–273
M. Focarete, C. Gualandi, S. Ramakrishna, Filtering media by electrospinning, Springer, Cham, Switzerland, 2018
B. Balusamy, A. Senthamizhan, T. Uyar, Functionalized electrospun nanofibers as a versatile platform for colorimetric detection of heavy metal ions in water: A review, Materials, 13 (2020), 2421
A. Senthamizhan, A. Celebioglu, B. Balusamy, T. Uyar, Immobilization of gold nanoclusters inside porous electrospun fibers for selective detection of Cu(II): A strategic