The results show that all the synthesized compounds displayed significant activity against S. epidermis, M. luteus, B. cereus, B. abortus and C. albicans when compared to standard drugs.
📌 3 Key Takeaways
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Objective & Hypothesis:A series of novel substituted isoxazolidine derivatives were synthesized by 1,3-dipolar cycloaddition reaction.
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Key Findings & Data:The structures of the synthesized compounds were characterized using spectroscopic methods.
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Conclusion & Impact:The results show that all the synthesized compounds displayed significant activity against S. epidermis, M. luteus, B. cereus, B. abortus and C. albicans when compared to standard drugs.
A series of novel substituted isoxazolidine derivatives were synthesized by 1,3-dipolar cycloaddition reaction. The structures of the synthesized compounds were characterized using spectroscopic methods. All the synthesized compounds were screened for their antibacterial activities against Gram-positive and Gram-negative bacteria and for their antifungal activities against a yeast strain. The results show that all the synthesized compounds displayed significant activity against S. epidermis, M. luteus, B. cereus, B. abortus and C. albicans when compared to standard drugs.
YANMAZ, V., DISLI, A., YAVUZ, S., OGUTCU, H., DILEK, G. (2019). Synthesis of Some Novel Isoxazolidine Derivatives via 1,3-Dipolar Cycloaddition and Their Biological Evaluation. Gazi University Journal of Science, Cilt: 32 - Sayı: 1, 78–89. https://ajindex.com/articles/254482
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