Journals / Çocuk Dergisi / 2011 / Cilt: 11 - Sayı: 3

Antiepileptic Choice of Pediatric Neurologists: Istanbul Pediatric Neurology Study Group Survey

Çocuk Nörologlarının Antiepileptik Tercihi: İstanbul Çocuk Nörolojisi Grubu Anket Çalışması

Pages
122–125
Publication Date
2011-07-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Results of the survey showed that drugs used for many years such as phenobarbital, valproic acid and carbamazepine are more preferred by pediatric neurologists

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To reveal antiepileptic drug preferences of the pediatric neurologist using questionnaire surveys.
📊
Key Findings & Data:Methods: The survey included neonatal seizures and 10 different patients with specific epileptic conditions.
💡
Conclusion & Impact:Conclusion: Results of the survey showed that drugs used for many years such as phenobarbital, valproic acid and carbamazepine are more preferred by pediatric neurologists
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Epilepsi · antiepileptik ilaç · çocuk nöroloğu

Abstract

Objective: To reveal antiepileptic drug preferences of the pediatric neurologist using questionnaire surveys. Methods: The survey included neonatal seizures and 10 different patients with specific epileptic conditions. Participants were asked for the first drug of choice and attitudes in the case of treatment failure. Results: In neonatal seizures, phenobarbital was the first choice of all participants. Valproate was the first choice of 100 % of the participants in myoclonic astatic epilepsy, of 85 % in photo-sensitive epilepsy, of 74 % in absence epilepsy, of 73 % in electrical status at slow sleep. For complex partial seizures, valproate, carbamazepine and oxcarbazepine were preferred equally. Conclusion: Results of the survey showed that drugs used for many years such as phenobarbital, valproic acid and carbamazepine are more preferred by pediatric neurologists

Özet

Amaç: Çocuk nörologlarının ilaç tercihlerini anket çalışmasıyla ortaya koymak. Yöntemler: Anket yenidoğan nöbetleri ve 10 farklı epileptik durum işaret eden vaka sunumlarını içermekteydi. Katılımcılardan bu durumlardaki ilk ilaç tercihleri, tedavi başarısızlığı durumunda ilaç ekleme veya ilaç değiştirme yaklaşımları sorgulandı. Bulgular: Yenidoğan nöbetlerinde tüm katılımcılar ilk tercih olarak fenobarbitali seçmişlerdi. Valproik asit katılımcıların miyoklonik astatik epilepside % 100’ünün, foto sensitif epilepside % 85’inin, absans epilepside % 74’ünün, uykudaki elektriksel statusta % 73’ünün ilk tercih ettikleri ilaç olmuştu. Kompleks parsiyel nöbetlerde valproik asit, karbamazepin ve okskarbazepin eşit oranda tercih edilmişti. Sonuç: Anket sonuçları çocuk nörologlarının fenobarbital, valproik asit ve karbamazepin gibi uzun yıllardır kullanılan antiepileptikleri daha çok tercih ettiklerini gösteriyo

🔖

Cite This Article

TATLI, B., EKİCİ, B. (2011). Antiepileptic Choice of Pediatric Neurologists: Istanbul Pediatric Neurology Study Group Survey. Çocuk Dergisi, Cilt: 11 - Sayı: 3, 122–125. https://ajindex.com/articles/246962

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (6)

  1. Wheless JW, Clarke DF, Carpenter D. Treatment of pediatric epilepsy: expert opinion, 2005. J Child Neurol 2005;20(Suppl 1):1-56
  2. Wheless JW, Clarke DF, Arzimanoglou A, Carpenter D. Treatment of pediatric epilepsy: European expert opinion, 2007 Epileptic Disord 2007;9:353-412. PMid:18077226 3. Neal EG, Chaffe H, Schwartz RH, et al. The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial. Lancet Neurol 2008;7:500-6.
  3. Hader WJ, Mackay M, Otsubo H, et al. Cortical dysplastic lesions in children with intractable epilepsy: role of complete resection. J Neurosurg 2004;100:110-7. PMid:14758938 5. Glauser T, Ben-Menachem E, Bourgeois B, et al. ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia 2006;47:1094- 120. http://dx.doi.org/10.1111/j.1528-1167.2006.00585.x PMid:16886973 6. Booth D, Evans DJ. Anticonvulsants for neonates with seizures. Cochrane Database Syst Rev 2004;4:CD004218. PMid:15495087 7. Levene M. The clinical conundrum of neonatal seizures. Arch Dis Child Fetal Neonatal Ed. 2002;86:75-7. http://dx.doi.org/10.1136/fn.86.2.F75 PMCid:1721380 8. Kossoff EH. Infantile spasms. Neurologist 2010;16:69-75. http://dx.doi.org/10.1097/NRL.0b013e3181d1416c PMid:20220440 9. Curatolo P, Seri S, Verdecchia M, Bombardieri R. Infantile spasms in tuberous sclerosis complex. Brain Dev 2001;23:502-7.
  4. Kälviäinen R, Nousiainen I. Visual field defects with vigabatrin: epidemiology and therapeutic implications. CNS Drugs 2001;3:217-30
  5. Kelley SA, Kossoff EH. Doose syndrome (myoclonic-astatic epilepsy): 40 years of progress. Dev Med Child Neurol 2010;52:988-9.
  6. Kilaru S, Bergqvist AG. Current treatment of myoclonic astatic epilepsy: clinical experience at the Children’s Hospital of Philadelphia. Epilepsia 2007;48:1703-7. http://dx.doi.org/10.1111/j.1528-1167.2007.01186.x PMid:17651420 13. Striano P, Coppola A, Pezzella M, et al. An open-label trial of levetiracetam in severe myoclonic epilepsy of infancy. Neurology 2007;69:250-4. http://dx.doi.org/10.1212/01.wnl.0000265222.24102.db PMid:17636062 14. Muslu B, Kilci O, Horasanli E, Dikmen B. Dramatic effect of levetiracetam on posthypoxic myoclonus: difficult weaning from mechanical ventilation. Clin Neuropharmacol