Journals / Çocuk Dergisi / 2015 / Cilt: 15 - Sayı: 2

The Relationship Between Asthma and Obesity in Children

Çocuklarda Astım ve Obezite İlişkisi

Pages
43–50
Publication Date
2015-04-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The consideration of this phenotype may conce- ivably bring about a more specific therapeutic approach.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The incidence of asthma in obese is generally found to be higher than in non-obese.
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Key Findings & Data:Apart from the studies related to epidemiologic, immunolo- gic, genetic and environmental factors, respiratory physio- logy and mechanics which demonstrate the relationship between obesity and asthma, in some studies contradictory have been reported.
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Conclusion & Impact:The consideration of this phenotype may conce- ivably bring about a more specific therapeutic approach.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Astım · obezite · çocuk

Abstract

The incidence of asthma in obese is generally found to be higher than in non-obese. Despite being thought to be a predisposing factor in the development of asthma, the mec- hanism and effects of obesity have not yet been well expla- ined. The relationship between obesity and asthma is tho- ught to be multifactorial and variable between individuals. Apart from the studies related to epidemiologic, immunolo- gic, genetic and environmental factors, respiratory physio- logy and mechanics which demonstrate the relationship between obesity and asthma, in some studies contradictory have been reported. In recent years, obesity -related ast- hma has been thought to be a different phenotype and “obesity -related asthma phenotype” concept has been proposed. The consideration of this phenotype may conce- ivably bring about a more specific therapeutic approach.

Özet

Obezlerde astım sıklığı, obez olmayanlara göre genellikle daha yüksek oranlarda bildirilmektedir. Obezitenin astım gelişimi için predispozan bir faktör olabileceği düşünülse de, neden olan mekanizmaların ve onların etkileri yeterin- ce açıklanamamıştır. Obezite ve astım arasındaki etkileşi- min multifaktöryel olduğu ve bireyler arasında değişken- likler gösterdiği düşünülmektedir. Astım ve obezite ilişkisi- ni ortaya koyan; epidemiyolojik, immünolojik, solunum fizyolojisi ve mekaniği, genetik ve çevresel faktörler ile ilgili çok sayıda çalışmanın varlığı ile birlikte, aksi yönde sonuç bildiren çalışmalar da bulunmaktadır. Son yıllarda obezite ilişkili astımın farklı bir fenotip olduğu düşünül- müş ve “obezite ile ilişkili astım fenotipi” kavramı öneril- miştir. Bu fenotipin göz önüne alınmasının obez astımlı hastalarda tedavi yaklaşımını daha spesifik hâle getireceği düşünülmektedir.

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Cite This Article

ÇEKİÇ, Ş., CANITEZ, Y., SAPAN, N. (2015). The Relationship Between Asthma and Obesity in Children. Çocuk Dergisi, Cilt: 15 - Sayı: 2, 43–50. https://ajindex.com/articles/246863

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