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Journals / Glokom Katarakt / 2017 / Cilt: 12 - Sayı: 1

Short Term Results of Combined Phacoemulsifi cation-Intraocular lens and Intravitreal Bevacizumab Injection in Patients with Exudative Type Age-related Macular Degeneration

Yaş Tip Yaşa Bağlı Makula Dejenerasyonlu Hastalarda Kombine Fakoemülsifi kasyon-Göz İçi Lensi ve İntravitreal Bevacizumab Enjeksiyonunun Kısa Dönem Sonuçları

Handan BARDAK
Yavuz BARDAK
Pages
16–20
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In short term, combined IVB and PE-IOL implantation was safe and effective for ARMD patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate efficacy and safety of combined intravitreal bevacizumab (IVB) injection and phacoemulsification (PE) intraocular lens implantation for patients with exudative type age-related macular degeneration (ARMD), in postoperative short term.Materials and Methods: In this study 36 eyes of 36 exudative ARMD patients (M/F: 15/21, mean age: 70.2±5.7years) had PE with intraocular lens (IOL) implantation and IVB injection (0.1 ml; 2.5 mg) at the end of surgery were included.
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Key Findings & Data:Ocular examinations were performed at preoperative, postoperative 1st day, 1st week and, 1st month.Results: Preoperative CMT was 342.0±57.7 (mean±standard deviation) micron and postoperative 1st month control CMT was 275.4±38.8 micron.
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Conclusion & Impact:Conclusion: In short term, combined IVB and PE-IOL implantation was safe and effective for ARMD patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate efficacy and safety of combined intravitreal bevacizumab (IVB) injection and phacoemulsification (PE) intraocular lens implantation for patients with exudative type age-related macular degeneration (ARMD), in postoperative short term.Materials and Methods: In this study 36 eyes of 36 exudative ARMD patients (M/F: 15/21, mean age: 70.2±5.7years) had PE with intraocular lens (IOL) implantation and IVB injection (0.1 ml; 2.5 mg) at the end of surgery were included. Efficacy and safety measures included corrected visual acuity (CVA), intraocular pressure (IOP) and central macular thickness (CMT). Ocular examinations were performed at preoperative, postoperative 1st day, 1st week and, 1st month.Results: Preoperative CMT was 342.0±57.7 (mean±standard deviation) micron and postoperative 1st month control CMT was 275.4±38.8 micron. There was mean 66.5±26.1 micron decrease in CMT. Preoperative IOP was 18.2±1.1mm Hg and postoperative 1st month control IOP was 17.7±1.4 mmHg. There was mean 0.5±1.2 mm Hg decrease. Preoperative CVA was 1.6±0.9 Log Mar and postoperative 1st month control CVA was 0.9±0.9 Log Mar. There was mean 0.7±0.6 Log Mar decrease. Conclusion: In short term, combined IVB and PE-IOL implantation was safe and effective for ARMD patients.

Özet

Amaç: Yaş tip yaşa bağlı makula dejenerasyonu (YBMD) olan hastalarda kombine fakoemülsifikasyon-göz içi lensi implantasyonu ile intravitreal bevacizumab enjeksiyonu tedavisinin ameliyat sonrası kısa dönem etkinlik ve güvenilirliğini araştırmak.Gereç ve Yöntemler: Bu çalışmaya yaş tip YBMD tanısı olan 36 hastanın (E/K=21/15, ortalama yaş 70.2±5.7 yıl) 36 gözü dahil edildi. Hastalara kombine fakoemülsifikasyon-göz içi lensi ile intravitreal bevacizumab enjeksiyonu (0.1 ml, 2.5 mg) uygulandı. Hastaların düzeltilmiş görme keskinlikleri (DGK), göz içi basıncı (GİB), santral makula kalınlığı (SMK), biomikroskopik ve fundus muayeneleri ameliyat öncesi, ameliyat sonrası 1.gün, 1. hafta, 1.ayda tekrarlandı ve karşılaştırıldı.Bulgular: Hastaların ameliyat öncesi SMK (342.0±57.7 mikron) (ortalama ± standart sapma) ölçümüne göre ameliyat sonrası 1.ay SMK (275.4±38.8 mikron) ölçümünde ortalama 66.5±26.1 mikron düşüş bulundu. Ameliyat öncesi DGK (1.6±0.9 Log Mar) ölçümüne göre ameliyat sonrası 1.ay DGK (0.9±0.9 Log Mar) ölçümündeki ortalama 0.7±0.6 Log Mar değişiklik tespit edildi. Ameliyat öncesi GİB (18.2±1.1mmHg) ölçümüne göre ameliyat sonrası 1.ay GİB (17.7±1.4mmHg) ölçümündeki ortalama 0.5±1.2mmHg azalma saptandı.Sonuç: Yaş tip YBMD olan hastalarda, kombine fakoemülsifikasyon-göz içi lensi ile intravitreal bevacizumab enjeksiyonu tedavisi kısa dönemde etkin ve güvenilirdir.

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Cite This Article

BARDAK, H., BARDAK, Y. (2017). Short Term Results of Combined Phacoemulsifi cation-Intraocular lens and Intravitreal Bevacizumab Injection in Patients with Exudative Type Age-related Macular Degeneration. Glokom Katarakt, Cilt: 12 - Sayı: 1, 16–20. https://ajindex.com/articles/226809

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