SavedAdd your journal

Journals / Glokom Katarakt / 2015 / Cilt: 10 - Sayı: 1

Efficacy and Safety of the Second Selective Laser Trabeculoplasty

İkinci Kez Yapılan Selektif Lazer Trabeküloplastinin Etkinliği ve Güvenilirliği

Handan BARDAK
Yavuz BARDAK
Hatice DALDAL
Pages
45–47
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There were no statistically significant differences in terms of reduction of IOP and success rates between the first and second SLT treatment.Conclusion: This study suggests that the repeat SLT is as effective and safe as the first SLT treatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To investigate the efficacy and safety of the second repeat Selective Laser Trabeculoplasty (SLT) in patients with primary open-angle glaucoma (POAG).Material and Method: Twenty eyes of 20 patients who underwent second SLT treatment for POAG were included in this retrospective study.
📊
Key Findings & Data:A second SLT was applied to patients whom intraocular pressure (IOP) remained above 21 mmHg despite a maximally tolerable medical therapy and an initial SLT.
💡
Conclusion & Impact:There were no statistically significant differences in terms of reduction of IOP and success rates between the first and second SLT treatment.Conclusion: This study suggests that the repeat SLT is as effective and safe as the first SLT treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To investigate the efficacy and safety of the second repeat Selective Laser Trabeculoplasty (SLT) in patients with primary open-angle glaucoma (POAG).Material and Method: Twenty eyes of 20 patients who underwent second SLT treatment for POAG were included in this retrospective study. A second SLT was applied to patients whom intraocular pressure (IOP) remained above 21 mmHg despite a maximally tolerable medical therapy and an initial SLT. A second SLT was performed on an average of 7.65±0.81 months after the initial treatment. The initial and second SLT treatments were compared in terms of IOP lowering effects, success rates and side effects.Results: The mean IOP decreases were 3.85±1.30 mmHg in the initial SLT and 3.35±1.8 mmHg in the second SLT; success rates were 55% in the initial SLT, 50% in the second SLT, 3 months after the SLT treatment. No significant side effects were observed in patients. There were no statistically significant differences in terms of reduction of IOP and success rates between the first and second SLT treatment.Conclusion: This study suggests that the repeat SLT is as effective and safe as the first SLT treatment.

Özet

Amaç: Primer açık açılı glokomlu (PAAG) hastalarda ikinci kez tekrar edilen Selektif Lazer Trabeküloplasti (SLT)'nin etkinliği ve güvenilirliğini araştırmak.Gereç ve Yöntem: Bu retrospektif çalışmaya PAAG nedeniyle ikinci defa SLT uygulanan 20 hastanın 20 gözü dahil edildi. Maksimum tolere edilebilen medikal tedavi ve bir defa SLT tedavisine rağmen göziçi basıncı (GİB) 21 mmHg'nın üzerinde olan hastalara ikinci defa SLT uygulandı. İlk SLT tedavisinden ortalama 7.65±0.81 ay sonra 2. SLT uygulandı. İlk ve ikinci SLT tedavileri, GİB'i düşürücü etkileri, başarı oranları ve yan etkileri açısından karşılaştırıldı. Bulgular: SLT sonrası 3. ayda ortalama GİB düşüşü, ilk kez yapılan SLT'de 3.85±1.30 mmHg, 2. kez yapılan SLT'de 3.35±1.08 mmHg; başarı oranı ilk kez yapılan SLT'de %55, 2. kez yapılan SLT'de %50 olarak tespit edilmiştir. Hastalarda belirgin bir yan etki gözlenmedi. SLT tedavisinin ilk kez ve 2. kez uygulanması arasında, GİB'i düşürme (p>0.05) ve başarı oranları (p>0.05) açısından istatistiksel olarak anlamlı fark bulunmadı.Sonuç: Bu çalışma ikinci kez tekrarlanan SLT'nin ilk kez yapılan kadar etkin ve güvenli olduğunu göstermektedir.

🔖

Cite This Article

BARDAK, H., BARDAK, Y., DALDAL, H. (2015). Efficacy and Safety of the Second Selective Laser Trabeculoplasty. Glokom Katarakt, Cilt: 10 - Sayı: 1, 45–47. https://ajindex.com/articles/203637

References (15)

  1. Kagan DB, Gorfinkel NS, Hutnik CM, et al. Mechanisms of selective laser trabeculoplasty: a review. Clin and Experiment Ophthalmol 2013.
  2. Barkana Y, Belkin M.Selective Laser Trabeculoplasty.Surv of Oph- thalmol 2007;52:634-54.
  3. Latina M, Park C. Selective targeting of trabecular meshwork cells: in vitro studies of pulse and continuous laser interactions. Exp Eye Res 1995;60:359-72.
  4. Shazly TA, Latina MA, Dagianis JJ, et al. Effect of prior cataract surgery on the long-term outcome of selective laser trabeculoplasty. Clin Ophthalmol 2011;5:377-80.
  5. Nagar M, Ogunyomade A, O'Brart DP, et al. Randomised, prospective study comparing selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma. Br J Ophthalmol 2005;89:1413-7.
  6. Damji KF, Shah KC, Rock WJ, et al. Selective laser trabeculoplasty vs argon laser trabeculoplasty: A prospective randomised clinical trial. Br J Ophthalmol 1999;83:718-22.
  7. Melamed S, Ben Simon GJ, Levkovitch-Verbin H. Selective laser tra- beculoplasty as primary treatment for open-angle glaucoma: a prospec- tive, nonrandomized pilot study. Arch Ophthalmol 2003;121:957-60. Latina MA, de Leon JM. Selective laser trabeculoplasty. Ophtalmol Clin North Am 2005;18:409-16.
  8. Zhao JC, Grosskreutz CL, Pasquale LR. Argon versus selective laser trabeculoplasty in the treatment of open angle glaucoma. Int Ophtal- mol Clin 2005;97-106.
  9. Avery N, Ang GS, Nicholas S, et al. Repeatability of primary selective laser trabeculoplasty in patients with primary open-angle glaucoma. Int Ophthalmol 2013;33:501-6.
  10. Hong BK, Winer JC, Martone JF, et al. Repeat selective laser trabeculoplasty.J Glaucoma 2009;18:180-3.
  11. Song J, Lee PP, Epstein DL, et al. High failure rate associated with 180 degrees selective laser trabeculoplasty. J Glaucoma 2005;14:400-8.
  12. Juzych MS, Chopra V, Banitt MR, et al. Comparison of long- term outcomes of selective laser trabeculoplasty versus argon laser trabe- culoplasty in open angle glaucoma. Ophthalmology 2004;111:1853-9.
  13. Wise JB, Witter SL. Argon laser therapy for open angle glaucoma. A pilot study. Arch Ophthalmol 1979;97:319-22.
  14. McHugh D, Marshall J, Fytche T, et al. Diode laser trabeculoplasty for primary open-angle glaucoma and ocular hypertension. Br J Ophthal- mol 1990;74:743-7.
  15. Pizzimenti JJ, Nickerson MM, Pizzimenti CE, et al. Selective laser trabeculoplasty for intraocular pressure elevation after intravitreal triamcinolone acetonide injection. Optom Vis Sci. 200