Journals / Glokom Katarakt / 2007 / Cilt: 2 - Sayı: 3

Fixed combinations in glaucoma management

Glokom tedavisinde fiks kombinasyonlar

Pages
149–156
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review we discuss the principles of glaucoma management and fixed combination therapy and examine the existing fixed combinations

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Topical medical therapy remains the first line of treatment in the management of glaucoma.
📊
Key Findings & Data:However, clinical studies have demonstrated that many patients with glaucoma require multiple medications to achieve adequate control of intraocular pressure.
💡
Conclusion & Impact:In this review we discuss the principles of glaucoma management and fixed combination therapy and examine the existing fixed combinations
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:İlaç tedavisi · kombinasyon · Glokom

Abstract

Topical medical therapy remains the first line of treatment in the management of glaucoma. However, clinical studies have demonstrated that many patients with glaucoma require multiple medications to achieve adequate control of intraocular pressure. For compliance, less toxicity of preservatives and cost effectiveness, combinations of commonly used drugs have been developed. In this review we discuss the principles of glaucoma management and fixed combination therapy and examine the existing fixed combinations

Özet

Glokom tedavisinde topikal ilaç kullanımı ilk tedavi seçeneğini oluşturmaktadır. Ancak yapılan klinik çalışmalar, glokom hastalarının çoğunda göz içi basıncının (GİB) yeterli oranda kontrol altına alınabilmesi için birden çok ilaç kullanımının gerekli olduğunu ortaya koymuştur. Bu nedenle tedaviye uyum, prezervan madde toksisitesi ve maliyet gibi faktörler göz önünde tutulduğunda sık kullanılan ajanların oluşturduğu fiks kombinasyonlar geliştirilmiştir. Bu makalede glokom yönetimi ve fiks kombinasyon tedavisinin temel özellikleri tartışılmış ve mevcut fiks kombinasyon ajanları incelenmiştir

🔖

Cite This Article

KURTULMUŞOĞLU, M. Ö., ÖNOL, M. (2007). Fixed combinations in glaucoma management. Glokom Katarakt, Cilt: 2 - Sayı: 3, 149–156. https://ajindex.com/articles/226685

References (9)

  1. Quigley HA: Number of people with glaucoma worlwide. Br J Ophthalmol. 1999;80:389-393.
  2. Sawada A, Kitazawa Y, Yamamoto T, et al.: Prevention of visual field defect progression with brovincamine in eyes with normaltension glaucoma. Ophthalmology. 1996;103:283-288.
  3. Huang X, Wu DY, Chen G, et al.: Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2- dependent mechanism. Invest Ophthalmol Vis Sci. 2003;44:347- 354. Leske MC, Heijl A, Hussein M, et al.: Factors of glaucoma progression and the effect of treatment: the early manifest glaucoma trial. Arch Ophthalmol. 2002;121:48-56. Terminology and Guidelines for Glaucoma. 2nd Edition 2003. American Academy of Ophthalmology: Preferred Practice PatternsTM: Open Angle Glaucoma. 2000;38. Goldberg I: Relationship between intraocular pressure and preservation of visual field in glaucoma. Surv Ophthalmol. 2003;48:1:3-7. Shields’ Textbook of Glaucoma fifth edition. 2005.
  4. Kent RA, Nussdorf JD, David R: Vitreus concentration of topically applied Brimonidine tartarate 0.2%. Ophthalmology. 2001;108:784-787. Collobaborative Normal Tension Glaucoma Study Group: The effectiveness of intraocular pressure reduction in the treatment of normal tension glaucoma. Am J Ophthalmol. 1998;126:498- 505. Lichter PR, Musch DC, Gilespie BW, et al.: Interm clinical outcomes in the Collaborative Initial Glaucoma treatment Study comparing inital treatment randomized to medications or surgery. Ophthalmology. 2001;108:1943-1953.
  5. Kass MA, Heuer DK, Higginbotham EJ, et al.: The Ocuar Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120:701-713.
  6. Patel SC, Spaeth GL: Compliance in patients prescribed eyedrops for glaucoma. Ophthalmic Surg. 1995;26:233-236.
  7. Levin MJ, Wormald RP, Migdal CS, et al.: The influence of prior therapy on the success of trabeculectomy. Arch Ophthalmol. 1990;108:1543-1548.
  8. Noecker RJ, Herrygers LA, Anwaruddin R: Corneal and conjonctival changes caused by commonly use glaucoma medications. Cornea. 2004;23:490-496.
  9. Miyake K, Ota I, Icbaraki N, et al.: Enhanced disruption of the blood-aqueus barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. Arch Ophthalmol. 2001;119:387- 395. Clineschmidt CM, Wiliams RD, Snyder E, et al.: A randomized trial in patients inadequately con