Journals / Glokom Katarakt / 2011 / Cilt: 6 - Sayı: 4

The relationship between corneal biomechanical properties and optic nerve head parameters in healthy subjects

Sağlıklı olgularda korneal biyomekanik özellikler ve optik sinir başı parametreleri arasındaki ilişki

Pages
215–218
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: The corneal biomechanical properties is not significantly correlated with the optic nerve head parameters in healthy subjects.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To evaluate the relationship between corneal biomechanical properties and parameters of optic nerve head in healthy subjects Materials and Methods: Forty-six eyes of 46 subjects were enrolled in this study.
📊
Key Findings & Data:Results: Mean age of 32 female and 14 male was 56.8±9.1 years.
💡
Conclusion & Impact:Conclusions: The corneal biomechanical properties is not significantly correlated with the optic nerve head parameters in healthy subjects.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the relationship between corneal biomechanical properties and parameters of optic nerve head in healthy subjects Materials and Methods: Forty-six eyes of 46 subjects were enrolled in this study. Central corneal thickness measured with ultrasonic pachymetry, corneal biomechanical properties measured with ocular response analyzer, and optic nerve parameters measured with optic cohorence tomography were obtained from all subjects. The relationship between corneal biomechanical parameters and optic nerve head parameters were evaluated with Pearson's correlation test. Results: Mean age of 32 female and 14 male was 56.8±9.1 years. No significant relationship was found between corneal biomechanical properties such corneal hysteresis and optic nerve head parameters such as disc area, rim area, rim volume, cup area, cup volume, and cup to disc ratio (p>0.05). Also, there is not significant correlation between CCT and optic nerve head parameters (p>0.05). Conclusions: The corneal biomechanical properties is not significantly correlated with the optic nerve head parameters in healthy subjects.

Özet

Amaç: Sağlıklı olgularda kornea biyomekanik özellikleri ile optik sinir başı parametreleri arasındaki ilişkiyi değerlendirmek. Gereç ve Yöntem: Çalışma kapsamına 46 sağlıklı hastanın 46 gözü alındı. Tüm olgulara detaylı oftalmolojik muayene yapıldı. Tüm olguların ultrasonik biyomikroskopi ile elde edilmiş santral kornea kalınlık (SKK) ölçümü, Oküler cevap analizörü ile ölçülmüş korneal biyomekanik özellikleri ve Optik kohorens tomografi ile ölçülmüş optik sinir başı parametreleri elde edildi. Korneal biyomekanik özellikler ile optik sinir başı parametreleri arasındaki ilişki Pearson korelasyon testi kullanılarak değerlendirildi. Bulgular: Otuz iki kadın ve 14 erkek olgunun yaş ortalaması 56.8±9.1 idi. Olgular korneal histerezis, korneal rezistans faktör gibi korneal biyomekanik özellikleri ile ve cup-disk oranı, rim alanı, rim hacmi, çukurluk alanı, çukurluk hacmi, optik sinir başı alanı gibi optik disk başı parametreleri arasında istatistiksel olarak anlamlı bir ilişki bulunmadı (p>0.05). Ayrıca, SKK ile optik sinir başı parametreleri arasında da anlamlı bir ilişki yoktu (p>0.05). Sonuç: Normal olgularda korneal biyomekanik özellikler optik sinir başı parametreleri ile anlamlı bir ilişki göstermemektedir.

🔖

Cite This Article

KARA, N., ALTINKAYNAK, H., BAZ, Ö., DÜNDAR, H., YÜKSEL, K., DEMİROK, A. (2011). The relationship between corneal biomechanical properties and optic nerve head parameters in healthy subjects. Glokom Katarakt, Cilt: 6 - Sayı: 4, 215–218. https://ajindex.com/articles/226504

References (13)

  1. Liu J, Roberts CJ.: Influence of corneal biomechanical properties on intraocular pressure measurement: quantitative analysis. J Cataract Refract Surg. 2005;31:146-155
  2. Luce DA.: Determining in vivo biomechanical properties of the cornea with an ocular response analyzer. J Cataract Refract Surg. 2005; 31:156-162
  3. Doughty MJ, Zaman ML.: Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. Surv Ophthalmol. 2000;44:367-408
  4. Congdon NG, Broman AT, Bandeen-Roche K, et al.: Central corneal thickness and corneal hysteresis associated with glaucoma damage. Am J Ophthalmol. 2006;141:868-875
  5. Cankaya AB, Elgin U, Batman A, et al.: Relationship between central corneal thickness and parameters of optic nerve head topography in healthy subjects. Eur J Ophthalmol. 2008;18:32-38
  6. Tomais G, Georgopoulos G, Koutsandrea C, et al.: Correlation of central corneal thickness and axial length to the optic disc and peripapillary atrophy among healthy individuals, glaucoma and ocular hypertension patients. Clin Ophthalmol. 2008;2:981-988
  7. Gunvant P, Porsia L, Watkins RJ, et al.: Relationships between central corneal thickness and optic disc topography in eyes with glaucoma, suspicion of glaucoma, or ocular hypertension. Clin Ophthalmol. 2008;2:591-599
  8. Lim L, Gazzard G, Chan Y-H et al.: Corneal biomechanics, thickness and optic disc morphology in children with optic disc tilt. Br J Ophthalmol. 2008;92:1461-1466
  9. Touboul D, Roberts C, Kerautret J et al.: Correlationsbetween corneal hysteresis, intraocular pressure, and corneal central pachymetry. J Cataract Refract Surg. 2008;34: 616-622
  10. Kourkoutas D, Georgopoulos G, Maragos A et al.: New nonlinear multivariable model shows the relationship between central corneal thickness and HRTII topographic parameters in glaucoma patients. Clin Ophthalmol. 2009;3:313-323
  11. Shah S, Laiquizzaman M, Mantry S, et al.: Ocular response analyser to assess hysteresis and corneal resistance factor in low tension, open angle glaucoma and ocular hypertension. Clin Experiment Ophthalmol. 2008;36:508-513
  12. Gordon MO, Beiser JA, Brandt JD.: The ocular hypertension treatment study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120:714-720
  13. Elizabeth Insull, Simon Nicholas FRANZCO, Ghee Soon Ang, et al.: Optic disc area and correlation with central corneal thickness, corneal hysteresis and ocular pulse amplitude in