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Journals / Glokom Katarakt / 2014 / Cilt: 9 - Sayı: 4

Pattern Electroretinogram and Optical Coherence Tomography in Patients with Ocular Hypertension

Oküler Hipertansiyonlu Olgularda Patern Elektroretinogram ve Optik Koherens Tomografi

Mualla HAMURCU
M. Sinan SARICAOĞLU
Semra KARA
Ahmet KARAKURT
Pages
249–252
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

However, it was thought that they might be of help in detecting early damage in OHT patients who were at high risk of conversion to glaucoma

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: We aimed to compare the pattern electroretinogram (PERG) amplitudes and retinal nerve fiber layer thicknesses (RNLF) determined by optical coherence tomography (OCT) in patients with ocular hypertension (OHT) and normal healthy subjects.
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Key Findings & Data:Material and Methods: Twenty-one normal subjects and 19 patients with OHT, totally 79 eyes of 40 patients were included in the study.
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Conclusion & Impact:However, it was thought that they might be of help in detecting early damage in OHT patients who were at high risk of conversion to glaucoma
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: We aimed to compare the pattern electroretinogram (PERG) amplitudes and retinal nerve fiber layer thicknesses (RNLF) determined by optical coherence tomography (OCT) in patients with ocular hypertension (OHT) and normal healthy subjects. Material and Methods: Twenty-one normal subjects and 19 patients with OHT, totally 79 eyes of 40 patients were included in the study. Groups were classified as OHT (Group 1, n=37) and the control group (Group 2, n= 42). ERG was performed in all patients in different sessions (MetrovisionMonPack model visualelectrophysiology device brand) and Stratus OCT (Zeiss Stratus OCT Model 3000 instrument). P50 and N95 wave amplitudes; RNFL thickness parameters were recorded and the data were statistically compared. Student t test and Mann-Whitney U test was used forthe statistical analysis. Statistical significance at p 0.05).Conclusion: In our study, there were no significant differences in both test methods between OHT group and normal population. However, it was thought that they might be of help in detecting early damage in OHT patients who were at high risk of conversion to glaucoma

Özet

Amaç: Oküler hipertansiyonlu olgularda patern elektroretinogram (PERG) amplitüdleri ve optik koherens tomografi (OKT) ile saptanan retina sinir lifi kalınlığı (RSLK) analiz sonuçlarının sağlıklı bireylerle karşılaştırılması amaçlandı.Gereç ve Yöntem: Çalışmamıza, 21 normal, 19 OHT'lu toplam 40 olgunun 79 gözü dahil edildi. Olgular OHT grubu (Grup 1; n=37) ve kontrol grubu (Grup 2; n=42) olarak sınıflandırıldı. Olguların tümüne farklı oturumlarda ERG (Metrovision marka MonPack model görsel elektrofizyoloji cihazı) ve Stratus OKT ( Zeiss Stratus OKT Model 3000 cihazı) incelemesi yapıldı. P50 ve N95 dalga amplitüdleri ile RSLK parametreleri kaydedildi ve veriler istatistiksel olarak karşılaştırıldı. İstatistiksel değerlendirmelerde Student t testi ve Mann-Whitney U testi kullanıldı. İstatistiksel anlamlılık sınırı p 0.05). Tartışma: Çalışmamızda OHT ve normal populasyon arasında, her iki test yönteminde de anlamlı farklılık izlenmemiştir. Ancak glokoma dönüşüm açısından yüksek riskli OHT olgularında erken hasarın belirlenmesinde yararlı olabilecekleri düşünüldü

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Cite This Article

HAMURCU, M., SARICAOĞLU, M. S., KARA, S., KARAKURT, A. (2014). Pattern Electroretinogram and Optical Coherence Tomography in Patients with Ocular Hypertension. Glokom Katarakt, Cilt: 9 - Sayı: 4, 249–252. https://ajindex.com/articles/226471

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