Journals / Gülhane Tıp Dergisi / 2006 / Cilt: 48 - Sayı: 2

A case of death due to fungal meningitis

Candida menenjitine bağlı bir ölüm olgusu

Pages
109–111
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The main purpose of presenting this case is to clarify the findings of fungal meningitis at autopsy and highlight the possible legal responsibility due to difficulties in diagnosing such cases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Meningitis caused by fungi are rarely seen.
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Key Findings & Data:Mortality and morbidity rates are still high among cases with fungal meningitis despite the developments in antimicrobial treatments and other supportive procedures.
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Conclusion & Impact:The main purpose of presenting this case is to clarify the findings of fungal meningitis at autopsy and highlight the possible legal responsibility due to difficulties in diagnosing such cases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Ölüm · Menenjit · fungal

Abstract

Meningitis caused by fungi are rarely seen. Mortality and morbidity rates are still high among cases with fungal meningitis despite the developments in antimicrobial treatments and other supportive procedures. In this report, a 22-year-old male admitted to hospital with a treatment-resistant headache and diagnosed to have fungal meningitis, but lost within three days after starting the antifungal therapy is presented. At autopsy, a purulant exudate was seen covering almost the entire surfaces of brain and meninges; and hyphae histologically consistent with candida albicans were detected especially in the meninges and the walls of the meningeal arteries, and death was determined to be due to fungal meningoencephalitis. The main purpose of presenting this case is to clarify the findings of fungal meningitis at autopsy and highlight the possible legal responsibility due to difficulties in diagnosing such cases.

Özet

Mantarlara bağlı menenjit olgularına nadir olarak rastlanmaktadır. Antimikrobiyal ve destek tedavi yöntemlerinde elde edilen gelişmeye rağmen mantarlara bağlı menenjit olgularında mortalite ve morbidite oranı yüksektir. Yirmi iki yaşında erkek olguya, medikal tedaviye rağmen geçmeyen baş ağrısı şikayetleri nedeniyle yapılan incelemede, candida menenjiti tanısı konulmuş, ancak antifungal tedaviye başlanmasından üç gün sonra kaybedilmiştir. Otopside, beyin yüzey ve kesitlerinde pürülan görünüm, histopatolojik incelemede beyin kesitlerinde yaygın Candida hifaları tespit edilerek ölümün fungal meningoensefalite bağlı olarak geliştiği tespit edilmiştir. Bu olgu, Candida menenjitine bağlı otopsi bulgularının ortaya konulması ve mantarlara bağlı menenjite tanı konulmasındaki güçlük nedeni ile ortaya çıkabilecek hukuki sorumluluğun vurgulanması amacıyla sunulmuştur.

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Cite This Article

TUĞCU, H., KARSLIOĞLU, Y., DEMİREL, B., ÖZSOY, S., CELASUN, B. (2006). A case of death due to fungal meningitis. Gülhane Tıp Dergisi, Cilt: 48 - Sayı: 2, 109–111. https://ajindex.com/articles/226366

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