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Journals / Astım Allerji İmmünoloji / 2011 / Cilt: 9 - Sayı: 1

Astımlı çocuklarda gastroözefageal reflü hastalığı ve atopi ile ilişkisi

Gastroesophageal reflux disease in asthmatic children and its relation with atopy

ÖZGE YILMAZ
HASAN ERHUN KASIRGA
Senem KADER
HASAN YÜKSEL
Pages
8–14
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, only respiratory symptoms and hospitalization improved in atopic children (p= 0.002 and p= 0.007 respectively).

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The aim of this study was to determine frequency of gastroesophegeal reflux disease (GERD) and influence of GERD treatment on respiratory findings in atopic and nonatopic children with asthma.
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Key Findings & Data:Materials and Methods: Thirty two nonatopic, 24 atopic children with asthma were enrolled in this retrospective study.
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Conclusion & Impact:However, only respiratory symptoms and hospitalization improved in atopic children (p= 0.002 and p= 0.007 respectively).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to determine frequency of gastroesophegeal reflux disease (GERD) and influence of GERD treatment on respiratory findings in atopic and nonatopic children with asthma. Materials and Methods: Thirty two nonatopic, 24 atopic children with asthma were enrolled in this retrospective study. GERD related respiratory symptoms and asthma severity parameters six months prior to and after pH monitoring were recorded. 24 hour pH monitoring results were also recorded. Results: Frequency of proximal GERD was 71.9% in atopic and 70.8% in nonatopic group (p= 0.93). Distal GERD frequencies were similar (66.7% and 68.8% in atopic and nonatopic groups respectively, p= 0.87). All parameters improved in nonatopic children after GERD treatment (p≤ 0.01). However, only respiratory symptoms and hospitalization improved in atopic children (p= 0.002 and p= 0.007 respectively).

Özet

Giriş: Bu çalışmanın amacı, atopik ve nonatopik astımlı çocuklarda gastroözefageal reflü hastalığı (GÖRH) sıklığını ve solunum yolu bulgularına GÖRH tedavisinin etkisini belirlemektir. Gereç ve Yöntem: Bu retrospektif çalışmaya 32 nonatopik, 24 atopik astımlı çocuk alındı. GÖRH ile ilişkili solunum sistemi belirtileri ve astım ağırlığı parametreleri pH monitörizasyondan önceki ve sonraki altı ay göz önüne alınarak kaydedildi. Ayrıca, 24 saatlik pH monitörizasyon sonuçları da kaydedildi. Bulgular: Proksimal GÖRH sıklığı atopik grupta %71.9, nonatopik grupta %70.8 saptandı (p= 0.93). Distal GÖRH sıklığı gruplar arasında benzerdi (sırasıyla atopik ve nonatopik gruplarda %66.7 ve %68.8, p= 0.87). Nonatopiklerde GÖRH tedavisi sonrasında tüm klinik parametrelerde düzelme mevcuttu (p≤ 0.01). Ancak, atopiklerde, sadece solunum sistemi belirtileri ve hastaneye yatışta düzelme görüldü (sırasıyla p= 0.002 ve p= 0.007).

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Cite This Article

YILMAZ, Ö., KASIRGA, H. E., KADER, S., YÜKSEL, H. (2011). Astımlı çocuklarda gastroözefageal reflü hastalığı ve atopi ile ilişkisi. Astım Allerji İmmünoloji, Cilt: 9 - Sayı: 1, 8–14. https://ajindex.com/articles/213162

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