Journals / Dicle Tıp Dergisi / 2015 / Cilt: 42 - Sayı: 4

The importance of background correction during calculation of the major salivary gland function in salivary gland scintigraphy

Tükürük bezi sintigrafisinde majör tükürük bezi fonksiyonları hesaplanmasında geri plan düzeltmesinin önemi

Pages
459–466
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

This study demonstrates that calculated uptake and excretion ratios of P and SM glands may differ according to the used background area.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to compare the parotid (P) and submandibular (SM) glands uptake and excretion ratios of 99mTc-pertechnetate, which were calculated by using the backgrounds drawn on five different areas.
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Key Findings & Data:Methods: Ninety-eight P and 98 SM glands of totally 48 patients were included in the study. 99mTc-pertechnetate salivary gland scintigraphy was performed in all patients.
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Conclusion & Impact:This study demonstrates that calculated uptake and excretion ratios of P and SM glands may differ according to the used background area.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to compare the parotid (P) and submandibular (SM) glands uptake and excretion ratios of 99mTc-pertechnetate, which were calculated by using the backgrounds drawn on five different areas. Methods: Ninety-eight P and 98 SM glands of totally 48 patients were included in the study. 99mTc-pertechnetate salivary gland scintigraphy was performed in all patients. Oral stimulation with lemon juice was made at 15th minute of the imaging. The 99mTc-pertechnetate uptake and excretion ratios of the P and SM glands were calculated separately without using any background, and by using the backgrounds drawn on wide frontal, narrow frontal, temporal, cervical and shoulder regions. These values were statistically compared with each other in pairwise manner. Results: The radioactivity uptake and excretion ratios of the P and SM glands calculated without using any background correction were statistically different from that calculated by using any background correction. In addition, the radioactivity uptake and excretion ratios of the P and SM glands calculated by using the backgrounds drawn on five different areas were mostly found statistically different from each other (p<0.05). Conclusion: Background correction is important during the calculation of the uptake and excretion ratios of P and SM glands. This study demonstrates that calculated uptake and excretion ratios of P and SM glands may differ according to the used background area.

Özet

Amaç: Bu çalışmanın amacı, parotis (P) ve submandibuler (SM) bezlerin 5 farklı bölgeye çizilen geri planlar kullanılarak hesaplanan 99mTc-perteknetatı konsantre ve ekskrete etme oranlarını karşılaştırmaktır. Yöntemler: Toplam 49 hastanın 98 P ve 98 SM bezi çalışmaya dahil edildi. Tüm hastalara 99mTc-perteknetat ile tükürük bezi sintigrafisi yapıldı. Görüntülemenin 15. dakikasında limon suyu ile oral stimülasyon gerçekleştirildi. Geri plan düzeltmesi yapılmaksızın ve geniş frontal, dar frontal, temporal, servikal ve omuz bölgesine çizilen geri planlar kullanılarak hesaplanan P ve SM bezlerin dola- şımdan 99mTc-perteknetatı tutma ve ekskrete etme oranları ayrı ayrı hesaplandı. Bu değerler ikili olarak istatistiksel olarak birbirleri ile karşılaştırıldı. Bulgular: P ve SM bezlerin geri plan düzeltmesi yapılmaksızın hesaplanan radyoaktivite tutulum ve ekskresyon oranları, geri plan düzeltmesi yapılarak hesaplanan oranlardan istatistiksel olarak anlamlı bir şekilde farklı bulundu. Ayrıca beş farklı bölgeye çizilen geri planlara göre hesaplanan P ve SM bezlerin radyoaktiviteyi tutma ve ekskrete etme oranları çoğunlukla istatistiksel olarak anlamlı bir şekilde farklı bulundu (p<0,05). Sonuç: P ve SM bezlerin perteknetatı tutma ve ekskrete etme oranlarını doğru hesaplamada geri plan düzeltmesi yapmak önemlidir. Bu çalışma P ve SM bezlerin perteknetatı tutma ve ekskrete etme oranlarının kullanılan geri plana göre değişebileceğini ortaya koymuştur.

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Cite This Article

TAŞDEMİR, B., DOSTBİL, Z., SEZGİN, İ. (2015). The importance of background correction during calculation of the major salivary gland function in salivary gland scintigraphy. Dicle Tıp Dergisi, Cilt: 42 - Sayı: 4, 459–466. https://ajindex.com/articles/212430

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References (8)

  1. Anjos DA, Etchebehere EC, Santos AO, et al. Normal values of [99mTc] pertechnetate uptake and excretion fraction by major salivary glands. Nucl Med Commun 2006;27:395- 403. Yousem DM, Kraut MA, Chalian AA. Major salivary gland imaging. Radiology 2000;216:19-29.
  2. Afzelius P, Nielsen MY, Ewertsen C, Bloch KP. Imaging of the major salivary glands. Clin Physiol Funct Imaging 2014 Oct 16. doi: 10.1111/cpf.12199. [Epub ahead of print] Cheng SC, Wu VW, Kwong DL, Ying MT. Assessment of post-radiotherapy salivary glands. Br J Radiol. 2011;84:393-402.
  3. Hays MT, Berman M. Pertechnetate distribution in man after intravenous infusion: a compartmental model. J Nucl Med 1977;18:898–904. de Rossi G, Focacci C. A computer-assisted method for semiquantitative assessment of salivary gland diseases. Eur J Nucl Med 1980;5:499–503. Klutmann S, Bohuslavizki KH, Kroger S, et al. Quantitative salivary gland scintigraphy. J Nucl Med Technol. 1999;27:20–26. Bohuslavizki KH, Brenner H, Klutmann S, et al. Implementation and indications for quantitative sialoscintigraphy. Laryngorhinootologie 1997;76:614–624. Wu CB, Xi H, Zhou Q, Zhang LM. The diagnostic value of technetium 99m pertechnetate salivary gland scintigraphy in patients with certain salivary gland diseases. J Oral Maxillofac Surg 2015;73:443-450.
  4. Malpani BL, Jaiswar RK, Samuel AM. Noninvasive scintigraphic method to quantify unstimulated secretions from individual salivary glands. Auris Nasus Larynx. 1999;26:453-456.
  5. Loutfi I, Nair MK, Ebrahim AK. Salivary gland scintigraphy: the use of semiquantitative analysis for uptake and clearance. J Nucl Med Technol 2003;31:81-85.
  6. Anjos DA, Etchebehere EC, Santos AO, et al. Normal values of [99mTc]pertechnetate uptake and excretion fraction by major salivary glands. Nucl Med Commun. 2006;27:395- 403. Senthilkumar B, Sathasivasubramanian S. The role of salivary gland scintigraphy in the evaluation of salivary gland dysfunction in uncontrolled Type II diabetic patients. World J Nucl Med. 2013;12:94-100.
  7. Fallahi B, Beiki D, Abedi SM, et al. Does vitamin E protect salivary glands from I-131 radiation damage in patients with thyroid cancer? Nucl Med Commun 2013;34:777-786.
  8. Zou Q, Jiao J, Zou MH, et al. Semi-quantitative evaluation of salivary gland function in Sjögren’s syndrome using salivary gland scintigraphy. Clin Rheumatol 2012;31:1699- 1705. Shimizu H, Matsushima S, Kinosada Y, et al. Evaluation of parotid gland function using equivalent cross-relaxation rate imaging applied magnetizat