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Journals / İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi / 2014 / Cilt: 4 - Sayı: 3

A pseudohypoparathyroidism case with rarely seen intracranial calcification in childhood

Çocukluk çağında ender görülen intrakraniyal kalsifikasyonla giden bir psödohipoparatiroidizm olgusu

Özlem KORKMAZ
HAZIM ALPER GÜRSU
Ali KAYA
Betül ALDEMİR ASLANER
Pages
214–217
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: We primarily considered the case as having PHPT Type 1b or Type 2 and started active vitamine D and calcium replacement therapies which improved clinical and laboratory findings.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Pseudohypoparathyroidism (PHPT) is characterized with end-organ resistance to parathormone (PTH) although normal hormone secretion.
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Key Findings & Data:It is divided into two groups as Type 1 and Type 2.
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Conclusion & Impact:Conclusion: We primarily considered the case as having PHPT Type 1b or Type 2 and started active vitamine D and calcium replacement therapies which improved clinical and laboratory findings.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Pseudohypoparathyroidism (PHPT) is characterized with end-organ resistance to parathormone (PTH) although normal hormone secretion. It is divided into two groups as Type 1 and Type 2. Furthermore, Type 1 PHPT is subdivided into 3 subgroups as ‘a’, ‘b’ and ‘c’. Case: A 10-year- old male patient was admitted to our department with numbness and spasm in hands and we have detected hypocalcemia, hyperphosphatemia and increa - sed parathormone levels. Cranial computed tomography revealed patchy calcific areas in phenotypically normal case. Conclusion: We primarily considered the case as having PHPT Type 1b or Type 2 and started active vitamine D and calcium replacement therapies which improved clinical and laboratory findings.

Özet

Giriş: Psödohipoparatiroidizm (PHPT); parathormon (PTH) salgılanması normal olmasına rağmen, hormona hedef organ direnci olması ile karakterize ender görülen bir klinik tablodur. Tip 1 ve tip 2 olmak üzere iki tipi vardır. Tip 1 PHPT; a, b ve c olmak üzere 3 alt grupta incelenir. Olgu: On yaşında erkek olgu ellerde uyuşma ve kasılma yakınması ile kliniğimize başvurdu. Yapılan laboratuvar incelemesinde hipokalsemi, hiperfosfatemi, parathor- mon yüksekliği saptandı. Fenotipik özellikleri normal olan olgunun çekilen kraniyal bilgisayarlı tomografik görüntülemesinde çok sayıda yamasal kalsifik alanlar izlendi. Sonuç: Olgu ön planda PHPT tip 1b veya 2 olarak değerlendirildi. Aktif D vitamini ve kalsiyum tedavisine klinik ve laboratuvar yanıt alındı.

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Cite This Article

KORKMAZ, Ö., GÜRSU, H. A., KAYA, A., ASLANER, B. A. (2014). A pseudohypoparathyroidism case with rarely seen intracranial calcification in childhood. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, Cilt: 4 - Sayı: 3, 214–217. https://ajindex.com/articles/210947

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