Journals / İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi / 2016 / Cilt: 6 - Sayı: 3

Acute generalized exanthematous pustulosis induced by amoxicillin-clavulanate

Amoksisilin-klavulanat kullanımına bağlı gelişen akut generalize ekzantematöz püstülozis olgusu

Pages
215–218
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As these reactions are known to emerge rarely emerge depending upon frequently used drugs, we have intended to draw attention to infections seen in childhood in the etiology of the rashes and drug reactions as well.

📌 3 Key Takeaways

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Objective & Hypothesis:Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous rash characterized by the abrupt onset of a widespread generalized pustular rash all over the body often accompanied by fever.
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Key Findings & Data:In the etiopathogenesis, there is a history of drug use in 90% of the cases, and occasionally hypersensitivity reactions to mercury or viral and bacterial infections are accused.
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Conclusion & Impact:As these reactions are known to emerge rarely emerge depending upon frequently used drugs, we have intended to draw attention to infections seen in childhood in the etiology of the rashes and drug reactions as well.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous rash characterized by the abrupt onset of a widespread generalized pustular rash all over the body often accompanied by fever. In the etiopathogenesis, there is a history of drug use in 90% of the cases, and occasionally hypersensitivity reactions to mercury or viral and bacterial infections are accused. Herein, a patient under amoxicillin-clavulanate therapy is presented who was diagnosed clinically as AGEP according to the scoring system by EuroSCAR group. As these reactions are known to emerge rarely emerge depending upon frequently used drugs, we have intended to draw attention to infections seen in childhood in the etiology of the rashes and drug reactions as well.

Özet

Akut generalize ekzantematöz püstülozis (AGEP), ani başlayan, ateşle birlikte tüm vücutta yaygın püstüler döküntü ile seyreden ender bir dermatozdur. Etyopatogenezde olguların %90'nında ilaç kullanımı mevcut olmakla birlikte, viral ve bakteriyal enfeksiyonlar ile civaya karşı aşırı duyarlılık reaksiyonları da suçlanmaktadır. Bu makalemizde, EuroSCAR çalışma grubunun skorlama sistemine göre klinik olarak AGEP tanısı konan, etken olduğu düşünülen amoksisilin-klavulanat tedavisinin kesilmesiyle semptomları gerileyen AGEP olgusu sunulmuştur. Ender olduğunu bildiğimiz bu reaksiyonların çocukluk çağında sık kullandığımız ilaçlara bağlı ortaya çıkması nedeniyle çocukluk döneminde görülen döküntülerin etiyolojisinde enfeksiyonlar kadar ilaç reaksiyonlarının da düşünülmesi gerektiği vurgulanmak istenmiştir.

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Cite This Article

NACAROĞLU, H. T., BENT, S., CEYLAN, Y., GAYRET, Ö. B., EROL, M. (2016). Acute generalized exanthematous pustulosis induced by amoxicillin-clavulanate. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, Cilt: 6 - Sayı: 3, 215–218. https://ajindex.com/articles/202501

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