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Journals / Kocatepe Tıp Dergisi / 2018 / Cilt: 19 - Sayı: 4

EFFECTS OF GLUTEN-FREE DIET ON HEMATOLOGICAL PARAMETERS IN CHILDREN WITH CELIAC DISEASE

ÇÖLYAK HASTASI ÇOCUKLARDA GLUTENSİZ DİYETİN HEMATOLOJİK PARAMETRELER ÜZERİNDEKİ ETKİLERİ

Semiha TERLEMEZ
Yavuz TOKGÖZ
Pages
126–130
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In addition, manyhemostasis parameters have been improved with thegluten-free diet.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: This study aims to evaluate the effects onhematological parameters of the gluten-free diet inceliac disease children.MATERIAL AND METHODS: Firstly, children with celiacdisease were identified in our clinic.
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Key Findings & Data:Hematologicalparameters of these patients were compared during thediagnosis and 6 months after the gluten-free diet.RESULTS: Sixty-seven of 97 children with celiac diseasewere included in the study.
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Conclusion & Impact:In addition, manyhemostasis parameters have been improved with thegluten-free diet.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Çölyak hastalığı · Anemi · Trombositoz

Abstract

OBJECTIVE: This study aims to evaluate the effects onhematological parameters of the gluten-free diet inceliac disease children.MATERIAL AND METHODS: Firstly, children with celiacdisease were identified in our clinic. Then, retrospectively,among these patients who were able to performgluten-free diet correctly were specified. Hematologicalparameters of these patients were compared during thediagnosis and 6 months after the gluten-free diet.RESULTS: Sixty-seven of 97 children with celiac diseasewere included in the study. Forty-four patients werefemale (66.7%), 22 patients were male (33.3%) and themean age of diagnosis was 7.1 ± 4.2 years. The most commonhematologic disorders in patients were thrombocytosisin 38 patients (57.5%) and anemia in 28 patients(42.2%). Twenty-four patients with anemia (36.6%) hadiron deficiency anemia, two patients with anemia (3%)had folate deficiency and one patient with anemia (1.5%)had vitamin B12 deficiency. After 6 months of gluten-freediet, only 8 patients (13%) had anemia. After the gluten-free diet, platelet counts decreased from 351.2 ± 11.0(103 / μL) to 310.5 ± 82.0 (103 / μL), leukocyte count decreasedfrom 8.82 ± 3.04 (103 / μL) to 8.04 ± 2.56 and meanplatelet volume decreased from 10.08 ± 1.07 fl to 9.5 ±1.19 fl. It was determined that there was a significant increasein hemoglobin, mean corpuscular volume and redcell distribution width values.CONCLUSIONS: The most common hematologicalfindings in children with celiac disease are thrombocytosisand anemia. An improvement has been observedin anemia after gluten-free diet. In addition, manyhemostasis parameters have been improved with thegluten-free diet.

Özet

AMAÇ: Çölyak hastalıklı çocuklarda glutensiz diyetin hematolojik

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Cite This Article

TERLEMEZ, S., TOKGÖZ, Y. (2018). EFFECTS OF GLUTEN-FREE DIET ON HEMATOLOGICAL PARAMETERS IN CHILDREN WITH CELIAC DISEASE. Kocatepe Tıp Dergisi, Cilt: 19 - Sayı: 4, 126–130. https://ajindex.com/articles/199436

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