Journals / Güncel Retina Dergisi / 2017 / Cilt: 1 - Sayı: 2

Drusen Types and Imaging Characteristics

Drusen Çeşitleri ve Görüntülenme Yöntemleri

Pages
116–123
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The subtypes of clinically detectable deposit, seen usually in the context of ageing or age related macular degeneration, are described in detail, together with appearance on imaging modalities

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The formation of drusen in aging eye is characterized by accumulation of extracellular material underneath the retinal pigment epithelium.
📊
Key Findings & Data:Usually drusen is evaluated in association with dry age related macular degeneration.
💡
Conclusion & Impact:The subtypes of clinically detectable deposit, seen usually in the context of ageing or age related macular degeneration, are described in detail, together with appearance on imaging modalities
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The formation of drusen in aging eye is characterized by accumulation of extracellular material underneath the retinal pigment epithelium. Usually drusen is evaluated in association with dry age related macular degeneration. Some types of drusen are recognised as normal consequence of aging, while some drusen types are associated with various inherited disorders and systemic conditions. The subtypes of clinically detectable deposit, seen usually in the context of ageing or age related macular degeneration, are described in detail, together with appearance on imaging modalities

Özet

Retina pigment epiteli altında ekstraselüler madde birikimleri drusen olarak tanımlanmaktadır. Drusen genelde yaşa bağlı makula dejenerasyonu ile olan ilişkisi bağlamında incelenmektedir. Bazı drusen çeşitleri yaşlanmanın normal bir sonucu olarak kabul edilmektedir, bazıları ise daha genç yaşlarda görülebilmektedir. Aynı zamanda bazı drusen tipleri farklı kalıtımsal ve sistemik hastalıklarla ilişkilendirilmektedir. Bu derlemede genelde normal yaşlanma sürecinin veya yaşa bağlı makula dejenerasyonun bir komponenti olan sert drusen, yumuşak drusen ve retiküler psödodrusen gibi drusen tiplerinin klinik ve görüntüleme bulgularının özetlenmesi amaçlanmıştır

🔖

Cite This Article

HOCAOĞLU, M., ARF, S., KARAÇORLU, M. (2017). Drusen Types and Imaging Characteristics. Güncel Retina Dergisi, Cilt: 1 - Sayı: 2, 116–123. https://ajindex.com/articles/197472

References (15)

  1. Ardeljan D, Chan CC. Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res. 2013;37:68-89
  2. Curcio CA, Johnson M. Structure, Function, and Pathology of Bruch’s Membrane. London: Elsevier, Inc.; 2013
  3. Miller JW. Age-related macular degeneration revisited–piecing the puzzle: the LXIX Edward Jackson memorial lecture. Am J Ophthalmol. 2013;155:1–35
  4. Wang AL, Lukas TJ, Yuan M, Du N, Tso MO, Neufeld AH. Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and agerelated macular degeneration. PLoS One. 2009;4:4160
  5. Wang L, Clark ME, Crossman DK, Kojima K, Messinger JD, Mobley JA, Curcio CA. Abundant lipid and protein components of drusen. PLoS One 2010;23;5(4):10329
  6. Rudolf M, Clark ME, Chimento MF, Li CM, Medeiros NE, Curcio CA. Prevalence and morphology of druse types in the macula and periphery of eyes with age-related maculopathy. Invest Ophthalmol Vis Sci 2008;49:1200–1209
  7. Mimoun G, Soubrane G, Coscas G. Macular drusen. J Fr Ophthalmol 1990; 13:511–30
  8. Ferris FL 3rd, Wilkinson CP, Bird A, Chakravarthy U, Chew E, Csaky K, Sadda SR; Beckman Initiative for Macular Research Classification Committee. Clinical classification of age-related macular degeneration. Ophthalmology 2013;120(4):844-51
  9. Age-Related Eye Disease Study Research Group.The age-related eye disease study (AREDS) system for classifying cataracts from photographs: AREDS report no
  10. Am J Ophthalmol 2001;131(2):167-75
  11. Rudolf M, Clark ME, Chimento MF, Li CM, Medeiros NE, Curcio CA. Prevalence and morphology of druse types in the macula and periphery of eyes with age-related maculopathy. Invest Ophthalmol Vis Sci 2008;49(3):1200-9
  12. Khan KN, Mahroo OA, Khan RS, et al. Differentiating drusen: Drusen and drusen-like appearances associated with ageing, age-related macular degeneration, inherited eye disease and other pathological processes. Prog Retin Eye Res 2016;53:70-106
  13. Khanifar AA, Koreishi AF, Izatt JA, Toth CA.Drusen ultrastructure imaging with spectral domain optical coherence tomography in age-related macular degeneration. Ophthalmology 2008;115(11):1883-90
  14. Arnold JJ, Fraco MQ, Soubrane G, Sarks SH, Coscas G. Indocyanine green angiography of drusen. Am J Ophthalmol 1997; 124:344–56
  15. Pauleikhoff D, Zuels S, Sheraidah GS, Marshall J, Wessing A, Bird AC. Correlation between biochemical composition and fluorescein binding of deposits in Bruch’s membrane.