Journals / Güncel Retina Dergisi / 2017 / Cilt: 1 - Sayı: 2

Classification and Pathogenesis in Dry-Form (Non-Neovascular) Age Related Macular Degeneration

Kuru Tip (Non-Neovasküler) Yaşa Bağlı Maküla Dejenerasyonunda Sınıflandırma ve Patogenez

Pages
105–111
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Visual acuity loss is more severe and faster in neovascular ARMD, late stages of geographic atrophy involving foveal center may also cause significant visual loss

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Age related macular degeneration is basically evaluated as non-neovascular (dry) and neovascular (wet) type.
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Key Findings & Data:Initial stages start with atrophy, drusen development in RPE-Bruch membrane level and pigmentary changes and in final stages may result in CNVM, disciform scar and geographic atrophic changes.
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Conclusion & Impact:Visual acuity loss is more severe and faster in neovascular ARMD, late stages of geographic atrophy involving foveal center may also cause significant visual loss
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Age related macular degeneration is basically evaluated as non-neovascular (dry) and neovascular (wet) type. Initial stages start with atrophy, drusen development in RPE-Bruch membrane level and pigmentary changes and in final stages may result in CNVM, disciform scar and geographic atrophic changes. Visual acuity loss is more severe and faster in neovascular ARMD, late stages of geographic atrophy involving foveal center may also cause significant visual loss

Özet

Yaşa bağlı makuler dejeneresans temel olarak non-neovasküler (kuru) ve neovasküler (yaş) tip olarak değerlendirilmektedir. Başlangıç aşamalarında maküler bölgede RPE-Bruch membranı düzeyinde atrofi, drusen gelişimi ve pigmenter değişiklikler ile izlenen hastalık, çevresel ve genetik faktörlerin etkisi altında ileri evrede KNVM ve diskiform skar gelişimi ya da jeografik atrofi gelişimi ile sonuçlanmaktadır. Görsel kayıplar neovasküler YBMD ile daha hızlı ve ağır gelişmekle birlikte, geç dönemde jeografik atrofinin fovea merkezini kapsaması ile de ciddi görme kayıpları yaşanabilmektedir

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Cite This Article

KAYIKÇIOĞLU, Ö. (2017). Classification and Pathogenesis in Dry-Form (Non-Neovascular) Age Related Macular Degeneration. Güncel Retina Dergisi, Cilt: 1 - Sayı: 2, 105–111. https://ajindex.com/articles/196202

References (14)

  1. Klaver CC, Wolfs RC, Vingerling JR, Hofman A, de Jong PT. Age-speci fic prevalence and causes of blindness andvisual impairment in an older population: the Rotterdam Study. Arch Ophthalmol 1998; 116(5):653–8
  2. Klein R, Klein BE, Tomany SC, Meuer SM, Huang GH. Ten-year incidence and progression of age-related maculopathy: the Beaver Dam eye study. Ophthalmology 2002;109(10):1767–79
  3. Mitchell P, Smith W, Attebo K, Wang JJ. Prevalence of age-related maculopathy in Australia. The Blue Mountains Eye Study. Ophthalmology 1995;102(10): 1450–60
  4. Sunness JS, Gonzalez-Baron J, Applegate CA, Bressler NM, Tian Y, Hawkins B, Barron Y, Bergman A. Enlargement of atrophy and visual acuity loss in the geographic atrophy form of age-related macular degeneration. Ophthalmology 1999;106(9):1768–79
  5. The Age-Related Eye Disease Study Group. Potential public health impact of AREDS results: AREDS report no 11. Arch Ophthalmol 2003;121:1621-4
  6. Age-Related Eye Disease Study Research Group: Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study Report Number 3. Ophthalmology 2000;107:2224-32
  7. Klein R, Meuer SM, Myers CE, et al. Harmonizing the Classification of Age-related Macular Degeneration in the Three-Continent AMD Consortium; Ophthalmic Epidemiology. 2014;21:14-23
  8. The Age-Related Eye Disease Study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the Age-Related Eye Disease Study Report Number 6. Am J Ophthalmol. 2001;132:668-81
  9. Sarks SH. Ageing and degeneration in the macular region: a clinico-pathological study. Br J Ophthalmol 1976;60(5):324–41
  10. Fleckenstein M, Schmitz-Valckenberg S, Sunness JS, Holz FG. Geographic atrophy. In: Holz FG, Pauleikhoff D, Spaide RF, Bird AC Age related macular degeneration. Second edition. Berlin, Springer Verlag 2013, 121-138
  11. Duke-Elder. System of Ophthalmology. Vol X Diseases of the retina. CV Mosby, St Louis 1967, 535-43
  12. Gass JDM. Drusen and disciform macular detachment and degeneration. Arch Ophthalmol 1973;90:206-17
  13. Bressler SB, Bressler NM, Sarks SH, Sarks JP. Age related macular degeneration: nonneovascular early AMD, intermediate AMD and geographic atrophy., chapter 60 In: Ryan SJ, Retina 4th edition, China, Elsevier-Mosby, 2006, 1041-74
  14. Bird AC, Bressler NB, Bressler SB et al. An international classification and grading system for age rel