Journals / Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi / 2017 / Cilt: 22 - Sayı: 2

Alkhurma Hemorrhagic Fever Virus

Alkhurma Hemorajik Ateş Virüsü

Pages
51–57
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this manuscript, information about the general characteristics of the virus, transmission and epidemiology, diagnosis, treatment and ways of protection were reviewed.

📌 3 Key Takeaways

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Objective & Hypothesis:Alkhurma hemorrhagic fever virus (AHFV) was first isolated in Jeddah, Saudi Arabia, in the 1990s from the blood of a butcher.
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Key Findings & Data:The name of the virus has been accepted by the International Commission on Taxation of Viruses as Alkhurma.
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Conclusion & Impact:In this manuscript, information about the general characteristics of the virus, transmission and epidemiology, diagnosis, treatment and ways of protection were reviewed.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Alkhurma hemorrhagic fever virus (AHFV) was first isolated in Jeddah, Saudi Arabia, in the 1990s from the blood of a butcher. The name of the virus has been accepted by the International Commission on Taxation of Viruses as Alkhurma. AHFV is also a member of the flavivirus family. Human infections have been linked to contact with small ruminants (sheep, goats) and camels, and consumption of un-pasteurized dairy products from infected animals (camel) has been reported as a mode of transmission so far. The most important factor contributing to the incidence of disease is the abundance of ticks containing a high dose of infectious AHFV that occur in the animal habitat. There are several factors that potentially influence the incidence of a global epidemic, including migrant workers, annual hajj and umrah pilgrimages, livestock trade between neighboring countries, and the presence of military personnel and their activities in this region. Fever, headache, and elevated levels of liver enzymes are almost seen in all patients. Common body pain, joint pain, loss of appetite, vomiting, leukopenia, thrombocytopenia, high creatinine phosphokinase and urea values are other major clinical conditions. Diagnosis is mostly made clinically. Presently, there are no antivirals or vaccines to treat or prevent AHFV. We should be attentive against the risk of moving this virus into our country through our citizens who return to Turkey especially after being in Saudi Arabia for pilgrimage which includes sacrificing small ruminants. Our people should be informed adequately and precautions should be taken against possible risks. Strict supervision and control should also be observed for the control of infected cattle. In this manuscript, information about the general characteristics of the virus, transmission and epidemiology, diagnosis, treatment and ways of protection were reviewed.

Özet

Alkhurma hemorajik ateş virüsü (AHFV), 1990'lı yıllarda Suudi Arabistan'da hastaneye başvuran kanamalı bir kasap kanından izole edilmiştir. Virüsün adı Uluslararası Virüs Taksonomisi Komitesi tarafından ilk tanımlandığı Alkhurma şekliyle kabul edilmiştir. Alkhurma Flaviviridae ailesi üyesidir. AHFV'nin bulaş ve epidemiyolojisindeki bilgiler kısıtlıdır. Eldeki verilere göre virüs doğrudan hayvanlardan temas yoluyla insanlara bulaşır. En yaygın bulaş yolları kesilen hayvanların kanına maruz kalınması veya çiğ sütünün tüketilmesidir. Hastalığın yayılmasına en önemli katkıyı yapanın ise hayvan yaşam alanlarında bulunan ve yüksek dozda AHFV içeren kenelerin bolluğu olduğu belirtilmiştir. Tüm dünyada ise epideminin sıklığından sorumlu faktörlerin başlıcaları; göçmen işçiler, yıllık hac ve umre sezonları, sınır komşularla hayvan ticareti ve askeri personelin bu bölgedeki aktiviteleridir. Ateş, baş ağrısı ve yükselmiş karaciğer enzim seviyeleri neredeyse hastaların tamamında görülmektedir. Yaygın vücut ağrıları, eklem ağrısı, iştahsızlık, kusma, lökopeni, trombositopeni, yüksek kreatinin fosfokinaz ve üre değerleri diğer başlıca klinik durumlardır. Tanı daha çok klinik olarak konulmaktadır. Halen hastalığı önlemek ya da tedavi etmek için aşı ya da antiviral ilaç yoktur. Ülkemize hem coğrafik konum itibariyle yakınlığı hem de özellikle hac ibadeti için Suudi Arabistan'a gidip geri dönen önemli sayıda vatandaşımız aracılığıyla bu virüsün ülkemize taşınması riskine karşı da dikkatli olunmalıdır. Halkımız yeterli düzeyde bilgilendirilmeli ve olası risklere karşı önlem alması sağlanmalıdır. İnfekte sığırların naklinin kontrolü için de sıkı denetim ve kontrollere uyulmalıdır. Bu derlemede, virüsün genel özellikleri, bulaş ve epidemiyolojisi, tanı, tedavi ve korunma yolları hakkında bilgilere yer verilmiştir.

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Cite This Article

Öz, S., BOLAT, M., ALTINDİŞ, M. (2017). Alkhurma Hemorrhagic Fever Virus. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Cilt: 22 - Sayı: 2, 51–57. https://ajindex.com/articles/196162

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