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Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2016 / Cilt: 22 - Sayı: 1

The Alterations in Peripheral Blood Components of Women with Abnormal Cervical Cytology

Mine KİSELİ
ASLI YARCI GÜRSOY
Egemen AKINCIOĞLU
EMRE GÖKSAN PABUÇCU
Gamze Sinem ÇAĞLAR
Hande Esra KOCA
Zehra EDEBAL
Haldun UMUDUM
Pages
36–39
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, absence of increased neutrophil counts and presence of lymphopenia in patients with abnormal cervical cytology, may indicate an early measure in cervical pathologies.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: To investigate the peripheral blood components, neutrophil/lymphocyte ratio (NLR) andplatelet/lymphocyte ratios (PLR) in cervical cytological abnormalities.
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Key Findings & Data:STUDY DESIGN: We retrospectively analyzed 185 cases with abnormal and 303 cases with normal cervicovaginal smears (CVS) with blood count profile, from a total number of 9286 patients.
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Conclusion & Impact:In this study, absence of increased neutrophil counts and presence of lymphopenia in patients with abnormal cervical cytology, may indicate an early measure in cervical pathologies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: To investigate the peripheral blood components, neutrophil/lymphocyte ratio (NLR) andplatelet/lymphocyte ratios (PLR) in cervical cytological abnormalities. STUDY DESIGN: We retrospectively analyzed 185 cases with abnormal and 303 cases with normal cervicovaginal smears (CVS) with blood count profile, from a total number of 9286 patients. RESULTS: Abnormal CVS results consisted of 137 (72%) ASC-US, 16 (8%) ASC-H, 19 (10%) L-SIL, 4(2%) H-SIL and 9 (4%) AGUS. NLR and PLR of abnormal CVS group were higher than control group(p<0.001). The lymphocyte count was significantly lower in abnormal CVS cases (p<0.001). The number of patients with neutrophilia (neutrophils >=70% of the total leukocytes) was similar among two groups(p>0.05).CONCLUSION: Neutrophilia is not observed in cervical preinvasive lesions whereas it is common in cervical cancer. In this study, absence of increased neutrophil counts and presence of lymphopenia in patients with abnormal cervical cytology, may indicate an early measure in cervical pathologies.

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Cite This Article

KİSELİ, M., GÜRSOY, A. Y., AKINCIOĞLU, E., PABUÇCU, E. G., ÇAĞLAR, G. S., KOCA, H. E., EDEBAL, Z., UMUDUM, H. (2016). The Alterations in Peripheral Blood Components of Women with Abnormal Cervical Cytology. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 22 - Sayı: 1, 36–39. https://ajindex.com/articles/189764

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