Journals / Güncel Retina Dergisi / 2018 / Cilt: 2 - Sayı: 3

Pathophysiology, Classification, Clinical findings, Diagnosis and Treatment of Secondary Epiretinal Membrane

Sekonder Epiretinal Membranda Patofizyoloji, Sınıflandırma, Klinik, Tanı ve Tedavi

Pages
268–272
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Treatment strategies are follow-up or surgery according to the level of vision and symptoms of the patient.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Epiretinal membrane (ERM) is a common disease of the vitreoretinal interface and is a fibrocelluler formation located on internal limiting membrane (ILM).
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Key Findings & Data:It is divided into idiopathic or secondary ERM according to the presence of underlying ocular disease.
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Conclusion & Impact:Treatment strategies are follow-up or surgery according to the level of vision and symptoms of the patient.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Epiretinal membrane (ERM) is a common disease of the vitreoretinal interface and is a fibrocelluler formation located on internal limiting membrane (ILM). It is divided into idiopathic or secondary ERM according to the presence of underlying ocular disease. Secondary ERM is associated with intraocular inflammation, retinal vascular diseases, trauma, laser photocoagulation, and intraocular surgery whereas idiopathic ERM is not associated with any ocular disease. Today, although the mechanism of formation of the secondary membranes is not fully understood, it is considered as abnormal wound healing. Treatment strategies are follow-up or surgery according to the level of vision and symptoms of the patient.

Özet

Epiretinal membran (ERM), vitreoretinal arayüzün yaygın bir hastalığıdır ve iç limitan membran (ILM) üzerinde yer alan fibroselüler bir oluşumdur. Altta yatan oküler hastalığının varlığına göre idopatik veya sekonder ERM olarak ikiye ayrılır. Sekonder ERM; intraoküler inflamasyon, retinal vasküler hastalıklar, travma, lazer fotokoagülasyon ve intraoküler cerrahi ile ilişkili iken, idiyopatik ERM herhangi bir oküler hastalıkla bağlantılı değildir. Günümüzde sekonder membranların oluşum mekanizması tam olarak netleşmese de anormal yara iyileşmesi olarak düşünülmektedir. Tedavi stratejileri, hastanın görme seviyesine ve semptomlarına göre takip ya da cerrahidir.

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Cite This Article

PEHLİVANOĞLU, S., ÖZ, Ö. (2018). Pathophysiology, Classification, Clinical findings, Diagnosis and Treatment of Secondary Epiretinal Membrane. Güncel Retina Dergisi, Cilt: 2 - Sayı: 3, 268–272. https://ajindex.com/articles/178145

References (10)

  1. Iwanoff A. Beitrage zur normalen und pathologischen Anatomie des Auges. Grafes Arch Clin Exp Opthalmol.1865;11: 135-170.
  2. Mitcell P, Smith W, Chey T, Wang JJ, Chang A. Prevalence and Associations of Epiretinal Membranes. The Blue Mountains Eye Study, Australia. Opthalmology 1997;104(6):1033-1040. Jacobsen CH. Epiretinal membranes. Optom Clin. 1996;5(1):77-94.
  3. Nicholson BJ, Zhou M, Rostamizadeh M, Mehta P, Agron E, Wong W, et al. Epidemiology of Epiretinal Membrane in a Large Cohort of Patients with Uveitis. Opthalmology 2014;121(12):2393-2398.
  4. Fong CS, Mitchell P, Rochtchina E, Hong T, de Loryn T, Wang JJ. Incedence and Progression of Epiretinal Membranes in Eyes After Cataract Surgery. Am J Ophthalmol. 2013;156(2):312-318.
  5. Triolo G, Pierro L, Parodi MB, De Benedetto U, Gagliardi M, Manitto MP,et al. Spectral domain optical coherence tomography findings in patients with retinitis pigmentosa. Ophthalmic Res. 2013;50(3):160-164.
  6. Katira RC, Zamani M, Berinstein DM, Garfinkel RA. Incidence and characteristics of macular pucker formation after primary retinal detachment repair by pars plana vitrectomy alone. Retina. 2008;28(5):744-748.
  7. Lehpamer B, Moshier E, Pahk P, Goldberg N, Ackert J, Godbold J, et al. Epiretinal membranes in uveitic macular edema:Effect on vision and response to therapy. Am J Ophthalmol. 2014;157(5):1048-1055.
  8. Appiah AP, Hirose T. Secondary causes of premacular fibrosis. Opthalmology. 1989;96(3):389-392. American Academy of Ophthalmology. Retina and Vitreus. Section 12. Epiretinal membrane.In: AAO’s Basic and Clin Sci Cours,United States of America. 2015:290-293
  9. Khaja HA, McCannel CA, Diehl NN, Mohney BG. Incidence and Clinical Characteristics of Epiretinal Membranes in Childeren. Arch Ophthalmol. 2008;126(5):632-636.
  10. Asato R, Yoshida S, Ogura A, Nakama T, Ishikawa K, Nakao S, et al. Comparison of gene expression profile of epiretinal membranes obtained from eyes with proliferative vitreoretinopathy to that of secondary epiretinal membranes. PLoS One. 2013;8(1): doi: 10.137. Bochaton-Piallat ML, Kapetanios AD, Donati G, Redard M,Gabbiani G, Pournas CJ. TGF-beta 1, TGF-beta receptor II and ED-A fibronectin expression in myofibroblasts of vitreoretinopathy. Invest Ophthalmol Vis Sci.2000;41(8):2336-2342. Urbančič M, Štunf Š, Milutinović Živin A, Petrovič D, Globočnik- Petrovič M. Epiretinal membrane inflammatory cell density might reflect the activity of proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci. 2014;55(12):8576-8582. 15-