Journals / Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi / 2016 / Cilt: 22 - Sayı: 1

Etiological Factors Concerning The Early Complications That Occur Following Coronary Artery Bypass Graft Surgery

Erken Dönemde Gelişen Komplikasyonlar ve İlişkili Koroner Arter Baypas Greftleme Cerrahisi Sonrası Etiyolojik Faktörler

Pages
16–23
DOI
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Discussion and Conclusion: It would be possible to decrease the rates of complications by preparing patients for the operation thoroughly during the preoperative period, by providing optimal treatment, complying with the myocardial protective techniques and reducing operating times.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Because coronary artery bypass graft (CABG) surgeries are becoming more common along with the advancements in anesthesia and surgery and changing patient profiles, greater number of complications are observed during the preoperative period.
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Key Findings & Data:Due to these complications, mortality and morbidity rates are increasing and length of stay in the intensive care unit is extended.
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Conclusion & Impact:Discussion and Conclusion: It would be possible to decrease the rates of complications by preparing patients for the operation thoroughly during the preoperative period, by providing optimal treatment, complying with the myocardial protective techniques and reducing operating times.
🔬Design:Review & Systematic Survey
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: Because coronary artery bypass graft (CABG) surgeries are becoming more common along with the advancements in anesthesia and surgery and changing patient profiles, greater number of complications are observed during the preoperative period. Due to these complications, mortality and morbidity rates are increasing and length of stay in the intensive care unit is extended. This study aimed to specify the etiological factors that cause the development of complications in CABG surgeries. Material and Methods: Files of 400 patients who were operated between January 2011 and December 2012 were reviewed retrospectively. Information concerning the patients’ ages, gender, weight, height, body mass index (BMI), ejection fraction, EuroSCORE (European system for cardiac operative risk evaluation score), presence of additional diseases, number of anastomoses carried out, the duration of cardiopulmonary bypass and aortic cross-clamping time, postoperative inotropic drug support, mechanical ventilation time, length of stay in the intensive care unit and in hospital, and the complications that occurred were recorded. The relationship between emerging complications and these variables was statistically analyzed. Results: The mean age of the patients was 61.4±9.4 years and 307 of them were males. Cardiac complication was the most frequently observed complication in patients with a rate of 29.8% which was followed by renal dysfunction (21%) and respiratory complications (12.3%). In 41.5% of the patients one complication while in 19% of them two and more complications developed. In multivariate logistic regression analysis, male gender, high BMIs, high EuroSCOREs, use of inotropic agents, prolonged CPB and the number of coronary anastomoses carried out were independent risk factors for complications. Extubation, and mechanical ventilation times, length of stay in intensive care unit and hospital were significantly prolonged in patients who developed complications (p=0.05). Discussion and Conclusion: It would be possible to decrease the rates of complications by preparing patients for the operation thoroughly during the preoperative period, by providing optimal treatment, complying with the myocardial protective techniques and reducing operating times.

Özet

Amaç: Anestezi ve cerrahideki gelişmelere bağlı olarak koroner arter baypas greftleme (KABG) ameliyatlarının giderek yaygınlaşması ve değişen hasta profili peroperatif dönemde daha fazla komplikasyonla karşılaşılmasına neden olmaktadır. Bu komplikasyonlara bağlı olarak mortalite ve morbidite oranları artmakta, hastanede ve yoğun bakımda kalış süresi uzamaktadır. Çalışmamızda, KABG cerrahisinde komplikasyon gelişimine neden olan etiyolojik faktörlerin saptanması hedeflenmiştir. Gereç ve Yöntem: Ocak 2011-Aralık 2012 tarihleri arasında opere olmuş 400 hastanın dosyası retrospektif olarak incelendi. Hastaların yaş, cinsiyet, kilo, boy, vücut kitle indeksi (VKİ), ejeksiyon fraksiyonu, EuroSCORE (European system for cardiac operative risk evaluation skoru), ek hastalık varlığı, yapılan anastamozların sayısı, aorta kros klemp ve KPB süreleri, postoperatif inotrop desteği, mekanik ventilatörde kalış süresi, yoğun bakımda ve hastanede kalış süresi, gelişen komplikasyonlar not edildi. Ortaya çıkan komplikasyonlarla bu değişkenler arasındaki ilişki istatiksel olarak araştırıldı. Bulgular: Hastaların ortalama yaşları 61.4±9.4 yıl ve 307'si erkekti. Hastalarda %29.8 oranıyla en sık kardiyak komplikasyon görüldü. Bunu renal disfonksiyon (%21) ve solunumsal komplikasyonlar (%12.3) izledi. Hastaların %41,5'inde bir komplikasyon, %19'unda ise iki ve üzerinde komplikasyon gelişti. Çok yönlü lojistik regresyon analizinde erkek cinsiyet, yüksek VKİ, yüksek EuroSCORE, inotropik ajan kullanımı, uzun KPB süresi ve yapılan koroner anastomoz sayısı komplikasyonlar için bağımsız risk faktörüydü. Komplikasyon gelişen hastaların ekstübasyon, mekanik ventilasyon,yoğun bakım ve hastane yatış süreleri anlamlı olarak uzamış bulundu (p=0.05). Tartışma ve Sonuç: Preoperatif dönemde hastaların operasyona ayrıntılı hazırlanması ve optimal sağaltımın yapılması, miyokard koruma tekniklerine uyulması ve operasyon sürelerinin azaltılması ile komplikasyon oranlarında azalma sağlanabilecektir.

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Cite This Article

MAVİLİ, İ., ŞAHUTOĞLU, C., PESTİLCİ, Z., KOCABAŞ, N. S., AŞKAR, F. Z. (2016). Etiological Factors Concerning The Early Complications That Occur Following Coronary Artery Bypass Graft Surgery. Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi, Cilt: 22 - Sayı: 1, 16–23. https://ajindex.com/articles/173430

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