Journals / Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi / 2017 / Cilt: 23 - Sayı: 4

Comparison of Two Different PEEP Levels in One Lung Ventilation

Düzeyinin Etkilerinin Karşılaştırılması Tek Akciğer Ventilasyonunda İki Farklı PEEP

Pages
116–120
DOI
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Conclusion: It was concluded that delivery of low tidal volume and 10 cm H2 O PEEP to the ventilated lung during thoracotomy made positive contributions to oxygenation without any adverse effects on hemodynamic, and respiratory mechanisms.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study aims to analyze the effects of two different positive end- expiratory pressure (PEEP) levels during single lung ventilation with low tidal volume (TV) on respiration and hemodynamics in patients undergoing thoracotomy.
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Key Findings & Data:Material and Methods: After the Hospital Education Planning Board approval and written consent were obtained 40 patients scheduled for thoracotomy were enrolled in the study.
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Conclusion & Impact:Conclusion: It was concluded that delivery of low tidal volume and 10 cm H2 O PEEP to the ventilated lung during thoracotomy made positive contributions to oxygenation without any adverse effects on hemodynamic, and respiratory mechanisms.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: This study aims to analyze the effects of two different positive end- expiratory pressure (PEEP) levels during single lung ventilation with low tidal volume (TV) on respiration and hemodynamics in patients undergoing thoracotomy. Material and Methods: After the Hospital Education Planning Board approval and written consent were obtained 40 patients scheduled for thoracotomy were enrolled in the study. When all patients were intubated with double- lumen endotracheal tube and one-lung ventilation (OLV) was initiated, the patients were randomized into two groups. Group 1 (n: 20) consisted of patients who underwent lung ventilation with 6 ml/kg TV and 5 cm H2 O PEEP; and Group 2 (n: 20) consisted of patients who underwent lung ventilation with 6 ml/ kg TV and 10 cm H2 O PEEP. Arterial blood gas samples were obtained from the patients during the study, and mean arterial pressure, heart rate, partial oxygen pressure (pO2 ), partial carbondioxide pressure (pCO2 ), peak airway pressures (PİP), plateau pressure values were recorded at 7 different time points namely T0: Supine position, before the induction, T1: double lung ventilation after induction, T2: OLV 15 minutes, T3: OLV 30 minutes, T4: OLV 45 minutes, T5: pre-extubation, supine position, T6: Postoperative 6th hour. Results: Mean arterial pressure and heart rate values were significantly lower at T1, T2, T3 ve T4 time points in Group 2; however, this decrease was within physiological limit. Group 2 patients had significantly higher PaO2 and lower PaCO2 values. At time points of T2, T3 and T4 when the patients were under OLV, PiP and plateau pressures in Group 2 patients were significantly higher (p<0.05). Conclusion: It was concluded that delivery of low tidal volume and 10 cm H2 O PEEP to the ventilated lung during thoracotomy made positive contributions to oxygenation without any adverse effects on hemodynamic, and respiratory mechanisms.

Özet

Amaç: Bu çalışma, torakotomi ameliyatı geçirecek hastalarda tek akciğer ventilasyonu sırasında düşük tidal volümle (TV) birlikte uygulanan 2 farklı ekspiryum sonu pozitif basınç (PEEP) düzeyinin solunum ve hemodinami üzerine etkilerini incelemek amacı ile yapıldı.Gereç ve Yöntem: Hastanemiz Eğitim Planlama Kurulu onayı ve yazılı onamı alındıktan sonra torakotomi ameliyatı uygulanacak 40 hasta çalışmaya alındı. Tüm hastalar çift lümenli endotrakeal tüp ile entübe edilerek tek akciğer ventilasyonuna (TAV) geçildiğinde rastgele 2 gruba ayrıldı. Grup 1 (n: 20) TAV sırasında ventile olan akciğere TV: 6 ml/kg ve 5 cmH2O PEEP uygulanan hastalar, Grup 2 (n: 20) TV: 6 ml/kg ve 10 cmH2O PEEP uygulanan hastalardan oluştu. Çalışma sırasında, hastalardan arter kan gazı örneği alınarak T0: Supin pozisyon, indüksiyon öncesi, T1: indüksiyon sonrası çift akciğer ventilasyonu, T2: TAV 15 dk., T3: TAV 30 dk., T4: TAV 45 dk., T5: Supin pozisyon extübasyon öncesi, T6: Postop 6. saat olmak üzere 7 dönemde ortalama arter basınçları, kalp atım hızı, parsiyel oksijen basıncı, parsiyel karbondioksit basıncı, pik havayolu basıncı (PİP) ve plato basınç değerleri kaydedildi. Bulgular: İki grup ortalama arter basınçları ve kalp atım hızı açısından karşılaştırıldığında T1, T2, T3 ve T4 periyodlarında Grup 2'de istatistiksel olarak anlamlı düşme görülse de değerler fizyolojik sınırlardaydı. Grup 2 hastalarında PaO2 değerlerinde yükselme ve PaCO2'de düşme anlamlıydı. TAV'na geçildiği T2, T3 ve T4 periyodlarında PİP ve plato basınçları Grup 2'de iki hastalarda anlamlı olarak yüksek bulundu (p<0.05).Sonuç: Çalışmamızın sonunda, torakotomi ameliyatları sırasında ventile edilen akciğere düşük TV ile 10 cmH2O PEEP uygulamasının hemodinamik ve solunum mekanikleri üzerine olumsuzluğa neden olmadan oksijenasyona olumlu katkılarda bulunduğu sonucuna varıldı

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Cite This Article

OKAY, T., YAKA, S., SİYAHKOÇ, E., YURTSEVEN, N., SİYAHKOÇ, İ. (2017). Comparison of Two Different PEEP Levels in One Lung Ventilation. Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi, Cilt: 23 - Sayı: 4, 116–120. https://ajindex.com/articles/167572

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References (12)

  1. Brismar B, Hedenstierna G, Lundquist J, et al. Pulmonary densities during anesthesia with muscular relaxation: a proposal of atelectasis. Anesthesiology 1985;62:422-8.
  2. Chang DW. Principles of mechanical ventilation In: Clinical application of mechanical ventilation. 1997, New York, Delmar Publishers
  3. Halbertsma FJ, van der Hoeven JG. Lung recruitment during mechanical positive pressure ventilation in the PICU: What Can Be Learned From The Literature? Anaesthesia 2005;60(8):779-90.
  4. Johanningman J. Prone positioning and inhaled nitric oxide: Synergistic therapies for acute respiratory distress syndrome. J Trauma 2001:5:589-96.
  5. Damia G, Mascheroni D, Croci M, Tarenzi L. Perioperative changes in functional residual capacity in morbidly obese patients. Br J Anaesth 1988;60:574-8.
  6. Fischer CW. Cohen E. An update on anesthesia for thoracoscopic surgery. Curr Opin Anaesthesiol 2010;23:7- 11.
  7. Fujiwara M, Abe K, Mashimo T. The effect of positive end-expiratory pressure and continuous positive airway pressure on the oxygenation and shunt fraction during one-lung ventilation with propofol anesthesia. J Clin Anesth 2001;13;473-7.
  8. Cohen E, Eisenkraft JB. Positive end-expiratory pressure during one-lung ventilation improves oxygenation tensions. J Cardiothorac Vasc Anesth 1996;10:578-82
  9. Inomata S, Nishikawa T, Saito S, Kihara S. Best PEEP during one-lung ventilation. Br J Anaesth 1997; 78:754-6.
  10. Kaymak Ç, Başar H. Sinir-kas kavşağının anatomi ve fizyolojisi. Türkiye Klinikleri J Anest Reanim 2005;3:109-15
  11. Bardoczky GI, d’Hollander AA, Cappello M, Yernault JC. Interrupted expiratory flow on automatically constructed flow volume curves may determine the presence of intrinsic positive end-expiratory pressure during one –lung ventilation. Anesth Analg 1998;86:880-4.
  12. Szegedi LL, Barvais L, Sokolow Y, Yernault JC, d’Hollander AA. Intrinsic positive end-expiratory pressure during one –lung ventilation of patients with pulmonary hyperinflation.Influence of low respiratory rate with unchanged minute volume. Br J Anaesth 2002;88:56-60. https:/