Journals / Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi / 2017 / Cilt: 23 - Sayı: 3

Anesthesia Management in Congestive Hepatopathy which Developed as an Outcome of Late-term Diagnosis of Constrictive Pericarditis

Konjestif Hepatopatide Anestezi Yönetimi Geç Tanılı Konstrüktif Perikardit Sonucu Gelişen Konjestif Hepatopatide Anestezi Yönetimi

Pages
105–108
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A decrease in baroreflex sensitivity has been shown as a component of cardiac cirrhosis also.Therefore, to prevent adrenergic depression that may be caused by anesthesia induction, induction agents were combined with ketamine and dobutamine.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Constrictive pericarditis is a rare clinical syndrome that can cause severe worsening of the diastolic filling.
📊
Key Findings & Data:A 49 yearold, 70 kg male patient had been admitted to a hospital due to loss of consciousness, shortness of breath, and jaundice.
💡
Conclusion & Impact:A decrease in baroreflex sensitivity has been shown as a component of cardiac cirrhosis also.Therefore, to prevent adrenergic depression that may be caused by anesthesia induction, induction agents were combined with ketamine and dobutamine.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Constrictive pericarditis is a rare clinical syndrome that can cause severe worsening of the diastolic filling. In this article, we aimed to present the perioperative anesthesia story of a case with a delayed diagnosis of cirrhosis due to constructive pericarditis. A 49 yearold, 70 kg male patient had been admitted to a hospital due to loss of consciousness, shortness of breath, and jaundice. He had peripheral edema, ascites, gastrointestinal bleeding, hepatomegaly, encephalopathy, antiHCV positivity,so the patient was diagnosed as having HCV cirrhosis+hepatic encephalopathy. HCV was negative in the renewed examinations, and the diagnosis was reconsidered On cardiology examination, he was diagnosed as constrictive pericarditis and decision of operation was made. Patient was operated on with high risk of neurological impairment with apathetic, slow-sense and responsive, partially oriented, moderate deceleration on electroencephalograms (EEG). Before anesthesia induction, blood pressure (114/60), heart rate (95 bpm), right-left near infrared spectroscopy (NIRS, rSO2 ) (43/45),patient state index (PSI) (95), SpO2 (97) were recorded as indicated.. During induction of anesthesia ketamine, midazolam, lidocaine, fentanyl, and rocuronium were used. Meanwhile, transamine and dobutamine infusions were initiated concurrently with induction. After induction, rightleft rSO2 (57/59), PSI (41), SEF (6.6/6.5). CVP (26) were measured. TEE was not performedbecause of the presence of esophageal varices. Intraoperatively, infusion of milrinone was initiated. After 4 hours he was extubated, infusions were terminated after 2 days. The left heart pulmonary venous return decreases during inspiration which shifts interventricular septum to the left and reduces left ventricular cavity so that stroke volume is reduced. The most important compensatory reflexive response to decrease in stroke volume is adrenergic stimulation. So it is important to maintain adrenergic stimulation during perioperative period. A decrease in baroreflex sensitivity has been shown as a component of cardiac cirrhosis also.Therefore, to prevent adrenergic depression that may be caused by anesthesia induction, induction agents were combined with ketamine and dobutamine.

Özet

Konstrüktif perikardit ender görülen ancak diyastolik doluşlarının bozulmasına neden olarak ciddi hasar oluşturabilen klinik bir sendromdur. Bu makalede geç tanı almış konstrüktif perikardit nedeniyle siroz tanısı konan bir olgunun perioperatif anestezi öyküsünü sunmayı amaçladık. Kırk dokuz yaş, 70 kg erkek hasta, daha önce bilinç kaybı, nefes darlığı, sarılık nedeniyle hastaneye kaldırıldı. Periferik ödem, asit, gastrointestinal kanama, hepatomegali, ensefalopati, antiHCV pozitifliği nedeniyle hastanın HCV sirozu + hepatik ensefalopati teşhisi kondu. Yenilenen tahlillerde HCV negatifti ve tanı tekrar gözden geçirildi. Kardiyolojik muayenesinde konstriktif perikardit tanısı alıp, ameliyat kararı verildi. Hasta apatik, kısmen oryante, Elektroensefalogram (EEG)'da orta derecede yavaşlama ile yüksek nörolojik riski altında tutuldu. Anestezi indüksiyonu öncesi kan basıncı 114/60, kalp hızı 95, sağ-sol near infrared spektroskopi (NIRS,rSO2) 43/45, patient state index (PSI) 95, SpO2 97. Anestezi indüksiyonunda, ketamin, midazolam, lidokain, fentanil, rokuronyum kullanıldı. İndiksiyonla birlikte transamin ve dobutamin infüzyonu başlatıldı. İndüksiyondan sonra sağ-sol rSO2 57/59, PSI 41, spektral kenar frekansları (SEF) 6.6 / 6,5, santral venöz basınç (CVP) 26. Transözofageal ekokardiyografi (TEE), özofagus varisleri nedeniyle yapılmak istenmedi. Ameliyat sırasında milrinon infüzyonu başlatıldı. Postoperatif 4 saat sonra ekstübe edildi, inotrop infüzyonları ise 2 gün sonra sonlandırıldı. Sol kalp pulmoner venöz dönüşü inspirasyon esnasında azalır. Bu, interventriküler septumu sola kaydırır ve sol ventrikül kavitesi ve strok volüm azalır. Strok volümdeki düşüşe verilen en önemli refleks yanıt adrenerjik uyarılmadır. Bu nedenle perioperatif dönemde adrenerjik uyarımı korumak önemlidir. Barorefleks duyarlılığında azalma da kardiyak sirozun bir bileşeni olarak gösterilmiştir. Bu nedenle anestezi indüksiyonunun neden olabileceği adrenerjik depresyonu önlemek için indüksiyon ajanları ketamin ve dobutamin ile kombine edilmiştir.

🔖

Cite This Article

AYKUT, A., DEMİR, Z. A., KUTAY, M. K., SERT, D. E., ÇATAV, Z. (2017). Anesthesia Management in Congestive Hepatopathy which Developed as an Outcome of Late-term Diagnosis of Constrictive Pericarditis. Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi, Cilt: 23 - Sayı: 3, 105–108. https://ajindex.com/articles/166082

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Braunwald's Heart Disease - A Textbook of Cardiovascular Medicine, Eugene Braunwald, WB Saunders Company; 6th Edition
  2. Manual of Cardiovascular Medicine- Eric J. Topol, Lippincott Williams & Wilkins, 2004 3. Cameron J, Oesterle SN, Baldwin JC, Hancock EW. The etiologic spectrum of constrictive pericarditis. Am Heart J 1987; 113:354.
  3. Ling LH, Oh JK, Schaff HV, et al. Constrictive pericarditis in the modern era: evolving clinical spectrum and impact on outcome after pericardiectomy. Circulation 1999;100:1380.
  4. Spodick DH. Pericardial diseases. In: Braunwald E, Zipes DP, Libby P (eds). Heart Disease a Textbook of Cardiovascular Medicine. 6th ed. Philadelphia: WB Saunders Comp, 2001:1823-76
  5. Forrest P. Anaesthesia and right ventricular failure. Anaesth Intensive Care 2009;37(3):370-85
  6. Ren X, Andrews AH. Cardiac cirrhosis. http://emedicine.medscape. com/article/151792-overview 8. Senni M, Redfield MM, Ling LH, Danielson GK, Tajik AJ, Oh JK. Left ventricular systolic and diastolic function after pericardiectomy in patients with constrictivepericarditis: Doppler echocardiographic findings and correlation with clinical status. J Am Coll Cardiol 1999;33(5):1182-8.
  7. Shiraishi M, Yamaguchi A, Muramatsu K, Kimura N, Yuri K, Matsumoto H, et al. Validation of Waffle procedure for constrictive pericarditis with epicardial thickening. Gen Thorac Cardiovasc Surg 2015;63(1):30-7.
  8. Sheth AA, Lim JK. Liver disease from asemptomatic constructive pericarditis. J Clin Gastroenterol 2008; 42: 956-8.
  9. Maleki M, Vakilian F, Amin A. Liver diseases in heart failure. Heart Asia 2011;3(1):143-9
  10. Garcia-Tsao G. Cirrhosis and its sequelae. In: Goldman L, Ausiello D, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 156