Journals / JAREM / 2020 / Cilt: 10 - Sayı: 2

The Effect of Using a Dose of Prophylactic Antibiotics on Spondylodiscitis in Lumbar Disc Surgery

Lomber Disk Cerrahisinde Bir Doz Profilaktik Antibiyotik Kullanılmasının Spondilodiskit Gelişimine Etkisi

Journal
JAREM
Pages
106–110
DOI
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Conclusion: Although most surgeons have a tendency to maintain antibiotic prophylaxis postoperatively or during hospitalization period, our study found that a single dose prophylactic antibiotic administered during anesthesia induction did not increase rate of spondylodiscitis by medical literature.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Although spondylodiscitis seen after lumbar discectomy is very rare, its incidence has been reported to be around 0.1-18.8% by many different authors.
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Key Findings & Data:Methods: Medical records of 1,154 patients who were operated in our hospital between 2007 and 2015 due to a single or two-level lumbar disc hernia were retrospectively extracted.
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Conclusion & Impact:Conclusion: Although most surgeons have a tendency to maintain antibiotic prophylaxis postoperatively or during hospitalization period, our study found that a single dose prophylactic antibiotic administered during anesthesia induction did not increase rate of spondylodiscitis by medical literature.
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Although spondylodiscitis seen after lumbar discectomy is very rare, its incidence has been reported to be around 0.1-18.8% by many different authors. The most common pathogen is Staphylococcus aureus. Methods: Medical records of 1,154 patients who were operated in our hospital between 2007 and 2015 due to a single or two-level lumbar disc hernia were retrospectively extracted. Of these patients, 554 were female and 600 were male. Discectomy operation was performed in 1,062 of these patients with single-level and 91 with two-level lumbar microdiscectomy. All of these patients were given a prophylactic single dose of cefazolin sodium in accordance with the recommendations of the surgical antimicrobial prophylaxis guidelines during anesthesia. Spondylodiscitis developed in 12 patients (1.03%). Comorbidities in patients who developed spondylodiscitis, isolated pathogens, antibiotic susceptibility, antibiotics used, and hospital stay were noted. Results: Of the 12 patients, 7 were female and 5 were male. Mean age was 45.75±14.16 years. Eleven of these patients underwent single level, one had 2 levels of lumbar microdiscectomy. Five patients underwent discectomy at L4-5 and 8 patients at L5-S1 levels. Three of these patients had S. aureus (25%), 4 had Staphylococcus epidermidis (33%) and 3 had Escherichia coli (25%) and 2 patients had no reproduction. The mean hospital stay was 29.45±3.98, and in patients without spondylodiscitöis it was 1.99±0.81, the two groups were significantly different from each other (p=0.0001). Conclusion: Although most surgeons have a tendency to maintain antibiotic prophylaxis postoperatively or during hospitalization period, our study found that a single dose prophylactic antibiotic administered during anesthesia induction did not increase rate of spondylodiscitis by medical literature.

Özet

Amaç: Lomber diskektomi sonrasında görülen spondilodiskit oldukça nadir olmakla beraber insidansı birçok farklı yazar tarafından %0,1-18,8 civarında bildirilmiştir. En sık görülen patojen Staphylococcus aureus’tur. Yöntemler: Hastanemizde 2007-2015 yılları arasında tek seviye veya iki seviye lomber disk hernisi nedeniyle opere etmiş olduğumuz 1.154 hastanın medikal kayıtları retrospektif olarak çıkartıldı. Bu hastaların 554’ü kadın, 600’ü erkek hasta idi. Bu hastaların 1.062’sine tek seviye, 91’ine 2 seviye lomber mikrocerrahi ile diskektomi operasyonu uygulandı. Bu hastaların tamamına anestezi esnasında cerrahi antimikrobiyal profilaksi rehberlerinin önerileri doğrultusunda profilaktik tek doz sefazolin sodyum verildi. Hastaların 12’sinde (%1,03) spondilodiskit gelişti. Spondilodiskit gelişmiş hastadaki komorbiditeler, izole edilen patojenler, antibiyotik duyarlılıkları, kullandıkları antibiyotikler ve hastanede kalış süreleri not edildi. Bulgular: On iki hastanın 7’si kadın, 5’i erkekti. Ortalama yaş 45,75±14,16 yıl idi. Bu hastaların 11’i tek seviye, 1 tanesi 2 seviye lomber mikrodiskektomi operasyonu geçirdi. Beş hasta L4-5 ve 8 hasta L5-S1 seviyelerinden diskektomi operasyonu geçirdi. Bu hastaların 3’ünde S. aureus (%25), 4’ünde Staphylococcus epidermidis (%33), 3’ünde Escherichia coli (%25) ve 2 hastada üreme olmadı. Ortalama hastanede kalış süresi 29,45±3,98, spondilodiskit olmamış hastalarda ise 1,99±0,81 olup iki grup birbirinden anlamlı derecede farklıydı (p=0,0001). Sonuç: Çoğu cerrahın antibiyotik profilaksisini postoperatif dönemde veya hastanın yattığı süre içerisinde devam ettirme eğilimi olmasına rağmen, çalışmamızda sadece anestezi indüksiyonu esnasında yapılan tek doz profilaktik antibiyotiğin spondilodiskit oranını tıbbi literatüre göre artırmadığı tespit edilmiştir.

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Cite This Article

DİREN, F., ONAL, M. B., CAN, H., KIRCELLİ, A. (2020). The Effect of Using a Dose of Prophylactic Antibiotics on Spondylodiscitis in Lumbar Disc Surgery. JAREM, Cilt: 10 - Sayı: 2, 106–110. https://ajindex.com/articles/165142

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