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Journals / Güncel Retina Dergisi / 2019 / Cilt: 3 - Sayı: 2

Pathogenesis of Retinal Vein Occlusion and Macular Edema

Retinal Ven Tıkanıklıklarında ve Maküla Ödeminde Patogenez

İSMAİL ÇAĞATAY ÇAĞLAR
Elvan KÜÇÜKKÖMÜRCÜ
Pages
72–75
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review discusses pathogenesis of branch retinal vein occlusion and macular edema due to branch retinal vein occlusion with the overview of anatomic, degenerative vessel wall changes and hematological and inflammatory factors.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Retinal vein occlusion is the most common retinal vascular disease after diabetic retinopathy.
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Key Findings & Data:Age, hypertension, diabetes, hyperlipidemia and atherosclerosis are the major risk factors.
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Conclusion & Impact:This review discusses pathogenesis of branch retinal vein occlusion and macular edema due to branch retinal vein occlusion with the overview of anatomic, degenerative vessel wall changes and hematological and inflammatory factors.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Retinal vein occlusion is the most common retinal vascular disease after diabetic retinopathy. Age, hypertension, diabetes, hyperlipidemia and atherosclerosis are the major risk factors. Studies revealed that the pathogenesis of this disease is multifactorial. It is reported that the retinal vein occlusion may occur as a result of combination of systemic changes like hemodynamic changes, vessel wall degeneration and blood hypercoagulability. Understanding of the pathogenesis of the disease is important to determine new and more potent treatment modalities. This review discusses pathogenesis of branch retinal vein occlusion and macular edema due to branch retinal vein occlusion with the overview of anatomic, degenerative vessel wall changes and hematological and inflammatory factors.

Özet

Retinal ven tıkanıkığı (RVT), diyabetik retinopatiden sonra en sık görülen retinal vasküler hastalıktır. İleri yaş, hipertansiyon, diyabet, hiperlipidemi ve ateroskleroz bilinen majör risk faktörleridir. Yapılan çalışmalarda, bu hastalığın patogenezinin multifaktöriyel olduğu ve temel olarak, hemodinamik değişiklikler, damar duvarı dejenerasyonu ve hiperkoagülabilite gibi sistemik durumların kombinasyonu sonucu oluşabileceği ileri sürülmüştür. Hastalığın patogenezinin anlaşılması, yeni ve daha etkili tedavi seçeneklerinin belirlenmesi açısından önemlidir. Bu derlemede retinal ven dal tıkanıklığı (RVDT) ve RVDT’ye bağlı gelişen maküla ödemi oluşumu, damar duvarındaki anatomik ve dejeneratif değişiklikler ile hematolojik ve inflamatuar faktörlerin rolü incelenerek ele alınmıştır.

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Cite This Article

ÇAĞLAR, İ. Ç., KÜÇÜKKÖMÜRCÜ, E. (2019). Pathogenesis of Retinal Vein Occlusion and Macular Edema. Güncel Retina Dergisi, Cilt: 3 - Sayı: 2, 72–75. https://ajindex.com/articles/165017

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