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Journals / Epilepsi / 2015 / Cilt: 21 - Sayı: 2

Epilepsy in Elderly Patients

Yaşlılarda Epilepsi

Gülistan HALAÇ
Halide Rengin BİLGEN
Gülşen KOCAMAN
Elvin NİFTALİYEV
Çiğdem DENİZ
Talip ASİL
Journal
Epilepsi
Pages
59–64
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

All patients responded well to monotherapy and have a good prognosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The incidence of new-onset epilepsy is high among the elderly.
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Key Findings & Data:This study presents the demographic characteristics, etiological factors, seizure types and response rates to treatment in a group of patients aged 65 years or over with delayed-onset epilepsy.
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Conclusion & Impact:All patients responded well to monotherapy and have a good prognosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: The incidence of new-onset epilepsy is high among the elderly. This study presents the demographic characteristics, etiological factors, seizure types and response rates to treatment in a group of patients aged 65 years or over with delayed-onset epilepsy. Methods: The study comprised a retrospective evaluation of the records of 43 patients aged 65 or older with a diagnosis of delayed-onset epilepsy who were admitted to the epilepsy clinic in the Neurology Department of Bezmialem University Faculty of Medicine. Results: Patient mean age was 74.9 (66–92 years). Underlying disease was found to be cerebrovascular disease in 37.2%. Based on seizure type, 67.4% (n=29) patients had partial-onset and 32.6% (n=14) had generalized seizure. Treatment protocol in 93% (n=40) of the patients was monotherapy antiepileptic drugs, the most commonly used being levetiracetam (53.5%). Assessment of drug side effects showed no complaint in 86% (n=37) of the patients. During the three months prior to the study, 95.3% of the patients had been seizure free. Conclusion: The study found cerebrovascular disease to be the most common etiological factor in delayed-onset epilepsy. Partial-onset secondary generalized seizure was the most common seizure type. All patients responded well to monotherapy and have a good prognosis.

Özet

Amaç: Yaşlılarda yeni başlangıçlı epilepsi insidansı oldukça yüksektir. Çalışmada, 65 yaş üstü geç başlangıçlı epilepsi tanısı alan hastaların demografik özellikleri, etiyolojik faktörleri, nöbet tipleri ve tedaviye yanıt oranları sunulmuştur ve literatür eşliğinde sonuçlar tartışılmıştır. Gereç ve Yöntem: Bezmialem Vakıf Üniversitesi Tıp Fakültesi, Nöroloji Anabilim Dalı Epilepsi Polikliniği’nden 65 yaş üstü geç başlangıçlı epilepsi tanısı ile takip edilen 43 olgu alındı. Hastaların tıbbi kayıtları geriye dönük olarak değerlendirildi. Bulgular: Kırk üç olgunun yaş ortalaması 74.9 (66–92) idi. Çalışmaya alınan hastalarda en sık serebrovasküler hastalık %37.2’de sorumlu olduğu düşünüldü. Hastaların nöbet tipleri değerlendirildiğinde; %67.4 (n=29) fokal, %32.6 (n=14) kişi jeneralize nöbet geçirmekteydi. Tedavi açısından değerlendirildiğinde %93’ü (n= 40) monoterapi alıyordu. En sık kullanılan antiepileptik ilaç levetirasetam (%53.5) idi. Hastaların ilaç yan etkilerini incelediğimizde %86’sında (n=37) herhangi bir ilaç yan etkisi yaşanmamıştı. Son üç ay içerisinde ki nöbet sıklığını incelediğimizde %95.3’ü nöbetsiz idi. Sonuç: Geç başlangıçlı epilepsi hastalarında en sık görülen etiyolojik neden serebrovasküler hastalık olup nöbet tipi çoğunlukla parsiyel başlangıçlı sekonder jeneralize tonik kloniktir, hastalar monoterapiye iyi yanıt verir ve prognoz iyi seyirlidir.

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Cite This Article

HALAÇ, G., BİLGEN, H. R., KOCAMAN, G., NİFTALİYEV, E., DENİZ, Ç., ASİL, T. (2015). Epilepsy in Elderly Patients. Epilepsi, Cilt: 21 - Sayı: 2, 59–64. https://ajindex.com/articles/162102

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