Journals / Astım Allerji İmmünoloji / 2011 / Cilt: 9 - Sayı: 1

Idiopathic hypereosinophilic syndrome: a case report

İdiyopatik hipereozinofilik sendrom: Bir olgu

Pages
52–55
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After treatment his skin lesions, leukocytosis and eosinophily were regressed. (Asthma Allergy Immunol 2011;9:51-54)

📌 3 Key Takeaways

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Objective & Hypothesis:Hypereosinophilic syndrome is a spectrum of disorders characterized by marked eosinophilic leukocytosis without identifiable cause or organ dysfunction.
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Key Findings & Data:We report 37 years old man applied with nonproductive cough and itchy skin eruptions for one year.
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Conclusion & Impact:After treatment his skin lesions, leukocytosis and eosinophily were regressed. (Asthma Allergy Immunol 2011;9:51-54)
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Hypereosinophilic syndrome is a spectrum of disorders characterized by marked eosinophilic leukocytosis without identifiable cause or organ dysfunction. We report 37 years old man applied with nonproductive cough and itchy skin eruptions for one year. At the physical examination there were nodular erythematous lesions on his upper extremity. We didn’t find any reason which can explain the eosinophily like allergic disease, mycotic infections, parasitic infections, malignancy and collagen tissue diseases with his anamnesis, clinical findings and laboratory tests. He was diagnosed as hypereosinopyhilic syndrome, and treated with hydroxiure. After treatment his skin lesions, leukocytosis and eosinophily were regressed. (Asthma Allergy Immunol 2011;9:51-54)

Özet

Otuz yedi yaşında erkek hasta, kliniğimize bir yıldır devam eden kuru öksürük ve kaşıntılı döküntü şikayetleriyle başvurdu. Hastada üst ekstremitede olan eritematöz nodüler lezyonlar vardı. Yapılan laboratuvar incelemesinde lökositoz ve eozinofili saptandı. Anamnez, klinik bulgular ve laboratuvar testleri sonucunda; allerji, mikotik infeksiyonlar, parazit infestasyonları, malignite, kollajen doku hastalıkları gibi eozinofiliyi açıklayan bir sebep bulunamadı. Hastaya idiyopatik hipereozinofilik sendrom tanısı konularak hidroksiüre tedavisi verildi. Hastanın deri bulguları tamamen düzeldi, lökositozu ve eozinofilisi geriledi. (Asthma Allergy Immunol 2011;9:51-54)

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Cite This Article

KÖSE, Ş., ÇAVDAR, G., GÖZAYDIN, A., YAVAŞ, S., GÖRGÜN, G. (2011). Idiopathic hypereosinophilic syndrome: a case report. Astım Allerji İmmünoloji, Cilt: 9 - Sayı: 1, 52–55. https://ajindex.com/articles/161915

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References (8)

  1. Chusid MJ, Dale DC, West BC, Wolff SM. The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore) 1975;54:1-27. Straumann A. Idiopathic eosinophilic gastrointestinal diseases in adults. Best Pract Res Clin Gastroenterol 2008;22:481-96.
  2. Bayramgürler D, Apaydın R, Namlı S. Eozinofilik dermatozlar. T Klin Tıp Bilimleri 2002;22:602-11.
  3. Ambarus V, Cosovanu A. The evolutionary characteristics of the hypereosinophilic syndrome. Rev Med Chir Soc Med Nat Lasi 1998;102:69-75.
  4. Kemmler N, Peitsch WK, Glorer E, Goerdt S. Hypereosinophilic dermatitis. An overlooked diagnosis? Hautarzt 2005;56:1060-7. Boxer LA. Hypereosinophilic syndrome. In: Behrman RE, Kliegman RM, Jenson HB (eds). Nelson Textbook of Pediatrics. 17th ed. Philadelphia: Saunders, 2004:710. Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH. NIH conference. The idiopathic hypereosinophilic syndrome: clinical, pathophysiologic and therapeutic considerations. Ann Intern Med 1982;97:78-92. ‹diyopatik hipereozinofilik sendrom: Bir olgu Idiopathic hypereosinophilic syndrome: a case report 54 Asthma Allergy Immunol 2011;9:52- Simon HU, Plotz SG, Dummer R, Blaser K. Abnormal clones of T cells producing interleukin-5 in idiopathic eosiniphilia. N Engl J Med 1999;341:1112-20.
  5. Weller PF, Bubley GJ. The idiopathic hypereosinophilic syndrome. Blood 1994;83:2759-79.
  6. Kim HS, Chun Y. Hypereosinophilic syndrome: correlation between clinical severity and cutaneous microthrombi. Int J Dermatol 2001;40:330-2. Finella B. The eosinophilias including the idiopathic hypereosinophilic syndrome. Br J Haematol 2003;121: 203-23.
  7. Pardanani A, Brockman SR, Paternoster SF, Flynn HC, Ketterling RP, Lasho TL, et al. FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia. Blood 2004;104:3038-45.
  8. Cools J, DeAngelo DJ, Gotlib J, Stover EH, Legare RD, Cortes J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med 2003;348:1201-14.