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Journals / Epilepsi / 2016 / Cilt: 22 - Sayı: 2

Somatosensory Evoked Potentials In Patients With Juvenile Myoclonic Epilepsy

Juvenil Miyoklonik Epilepsi Hastalarında Duysal Uyandırılmış Potansiyeller

Zeynep AYDIN ÖZEMİR
Zeliha MATUR
Betül BAYKAN
Ali Emre ÖGE
Journal
Epilepsi
Pages
41–45
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In the present review, the findings of previous studies concerned with SEP in JME patients are summarized, and their importance regarding JME etiopathogenesis and related clinical findings is discussed.

📌 3 Key Takeaways

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Objective & Hypothesis:While a small number of studies dealing with somatosensory evoked potential (SEP) have demonstrated hyperexcitability in the primary somatosensory cortex of juve-nile myoclonic epilepsy (JME) patients, the underlying mechanisms have yet to be illuminated.
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Key Findings & Data:Determination of higher cortical SEP responses in some JME patients and recordings of very high amplitude responses, called “giant SEP,” in a specific subgroup may indicate a clinical and possibly genetic heterogeneity within JME patients.
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Conclusion & Impact:In the present review, the findings of previous studies concerned with SEP in JME patients are summarized, and their importance regarding JME etiopathogenesis and related clinical findings is discussed.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

While a small number of studies dealing with somatosensory evoked potential (SEP) have demonstrated hyperexcitability in the primary somatosensory cortex of juve-nile myoclonic epilepsy (JME) patients, the underlying mechanisms have yet to be illuminated. Determination of higher cortical SEP responses in some JME patients and recordings of very high amplitude responses, called “giant SEP,” in a specific subgroup may indicate a clinical and possibly genetic heterogeneity within JME patients. In the present review, the findings of previous studies concerned with SEP in JME patients are summarized, and their importance regarding JME etiopathogenesis and related clinical findings is discussed.

Özet

Jüvenil miyoklonik epilepsi (JME) hastalarında literatürde az sayıda bildirilmiş olan duysal (somatosensoryel) uyandırılmış potansiyel (SEP) çalışmalarında bazı JME hastalarında primer somatosensoryel kortekste hipereksitabiliteye işaret eden bulgular saptanmıştır ve bu bulguların elde edilmesinin altında yatan süreçler henüz aydınlatılmamıştır. Jüvenil miyoklonik epilepsi hastalarının tümünde değil de bazılarında kortikal SEP yanıtlarının yüksek saptanması ve hatta bunların içlerinden bazılarında da “dev SEP” olarak tanımlanan çok yüksek amplitüdlü yanıtların bulunması, SEP bulgularının JME olguları içerisinde bir klinik ve olası genetik heterojeniteye işaret ettiği izlenimi oluşturmaktadır. Bu yazıda, JME hastalarında şimdiye kadar yapılmış SEP çalışmalarının bulguları değerlendirildi ve JME etiyopatogenezi ve klinik tablo açısından olası önemi tartışıldı.

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Cite This Article

ÖZEMİR, Z. A., MATUR, Z., BAYKAN, B., ÖGE, A. E. (2016). Somatosensory Evoked Potentials In Patients With Juvenile Myoclonic Epilepsy. Epilepsi, Cilt: 22 - Sayı: 2, 41–45. https://ajindex.com/articles/159944

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