Journals / Astım Allerji İmmünoloji / 2012 / Cilt: 10 - Sayı: 1

Eosinophilic esophagitis in children

Çocuklarda eozinofilik özefajit

Pages
1–9
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A teamwork consisting of an allergist, gastroenterologist and dietician is required for the diagnosis, treatment and follow-up of disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Eosinophilic esophagitis is a rare form of food allergy and chronic inflammatory disorder characterized by eosinophilic infiltration of the esophageal mucosa without involving other parts of the gastrointestinal system.
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Key Findings & Data:Its incidence is thought to be between 1-2.7/10.000 per year and has been recognized increasingly over the last decade.
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Conclusion & Impact:A teamwork consisting of an allergist, gastroenterologist and dietician is required for the diagnosis, treatment and follow-up of disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Eosinophilic esophagitis is a rare form of food allergy and chronic inflammatory disorder characterized by eosinophilic infiltration of the esophageal mucosa without involving other parts of the gastrointestinal system. Its incidence is thought to be between 1-2.7/10.000 per year and has been recognized increasingly over the last decade. Food and aero- allergens is thought to be responsible for its etiology. The symptoms depend on age, but the most characterictic complaints are those of gastroesophageal reflux in children. The absolute diagnosis of eosinophilic esophagitis is by histopathological examination. Patients should be investigated for atopic disorders due to frequent comorbidities with other allergic disorders. Nowadays, dietary management and topical corticosteroid regimen are the treatment of the disease. Remission is rare and the single complication is esophageal stricture. A teamwork consisting of an allergist, gastroenterologist and dietician is required for the diagnosis, treatment and follow-up of disease.

Özet

Eozinofilik özefajit, besin allerjilerinin nadir bir formu olup gastrointestinal sistemde sadece özefagus mukozasının eozinofilik lökositlerle infiltre olduğu kronik inflamatuvar bir hastalıktır. İnsidansının yıllık 1-2.7/10.000 olduğu tahmin edilmekte ve son yıllarda sıklığı giderek artmaktadır. Etyolojide besin allerjenleri ve aeroallerjenler suçlanmaktadır. Şikayetler hastanın yaşına göre değişir, ancak çocuklarda gastroözefageal reflüye bağlı yakınmalar en sık olanıdır. Hastalığın kesin tanısı özefagusun histopatolojik incelenmesiyle konulur. Çoğunlukla atopi eşlik ettiği için, olgular allerjik hastalıklar açısından araştırılmalıdır. Günümüzde hastalığın tedavisinde diyet ve topikal kortikosteroidler verilmektedir. Remisyon nadir olup bilinen tek komplikasyonu özefagusta darlık oluşmasıdır. Hastalığın tanı, tedavi ve izleminde allerjist, gastroenterolog ve diyetisyenden oluşan bir ekip çalışması gerekmektedir.

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Cite This Article

TOPAL, E., BAKIRTAŞ, A. (2012). Eosinophilic esophagitis in children. Astım Allerji İmmünoloji, Cilt: 10 - Sayı: 1, 1–9. https://ajindex.com/articles/158154

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