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Journals / Astım Allerji İmmünoloji / 2013 / Cilt: 11 - Sayı: 2

Stevens-Johnson syndrome: A case due to hydroxychloroquine

Hidroksiklorokine bağlı Stevens-Johnson sendromlu olgu

Rabia Bilge ÖZDEMİR ÖZGÜL
Ferda BİLGİR
Timur PIRILDAR
Cengiz KIRMAZ
Pages
123–127
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, a patient with Stevens-Johnson syndrome due to hydroxychloro- quine is reported.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Stevens-Johnson syndrome is a rare but life-threat- ening mucocutaneous skin reaction that is often caused by drugs.
📊
Key Findings & Data:The most common causes of mortality are sepsis, gastrointestinal bleeding and fluid- electrolyte imbalance.
💡
Conclusion & Impact:In this article, a patient with Stevens-Johnson syndrome due to hydroxychloro- quine is reported.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Stevens-Johnson syndrome is a rare but life-threat- ening mucocutaneous skin reaction that is often caused by drugs. The most common causes of mortality are sepsis, gastrointestinal bleeding and fluid- electrolyte imbalance. In this article, a patient with Stevens-Johnson syndrome due to hydroxychloro- quine is reported.

Özet

Stevens-Johnson sendromu sıklıkla ilaçlara bağlı olarak gelişen nadir, fakat hayatı tehdit edebilen mukokütanöz bir deri reaksiyonudur. Ölüm nedenleri en sık sepsis, gastrointestinal sistem kanması ve sıvı-elektrolit dengesizliğidir. Bu makalede bağ doku hastalığı nedeniyle hidroksiklorokin kullanımı sonrası vücutta yaygın maküler döküntü meydana gelen hidroksiklorokine bağlı Stevens- Johnson sendromu tanısı almış bir olgu sunulmuştur.

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Cite This Article

ÖZGÜL, R. B. Ö., BİLGİR, F., PIRILDAR, T., KIRMAZ, C. (2013). Stevens-Johnson syndrome: A case due to hydroxychloroquine. Astım Allerji İmmünoloji, Cilt: 11 - Sayı: 2, 123–127. https://ajindex.com/articles/158150

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References (14)

  1. Harr T, French LE. Toxic epidermal necrolysis and Stevens-Johnson syndrome. Orphanet J Rare Dis 2010;5:39
  2. Bolognia J, Jorizzo J, Rapini R. Dermatology. London: Elsevier, 2003:291-9
  3. Bastuji-Garin S, Rzany B, Stern RS, Shear NH, Naldi L, Roujeau JC. Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch Dermatol 1993;129:92-6
  4. Rzany B, Correia O, Kelly JP, Naldi L, Auquier A, Stern R. Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis during first weeks of antiepileptic therapy: a case-control study. Study Group of the International Case Control Study on Severe Cutaneous Adverse Reactions. Lancet 1999;353:2190-4
  5. Giles JT, Bathon JM. Management of rheumatoid arthritis: synovitis. In: Hochberg MC, Silman AJ, Smolen JS, Weinblatt M, Weisman MH (eds). Rheumatology. 4th ed. Philadelphia: Mosby Elsevier, 2008:887-96
  6. Yurdakul S. Uzun etkili ilaçlar. Türkiye Klinikleri J Int Med Sci 2006;2:52-9
  7. Leckie MJ, Rees RG. Stevens-Johnson syndrome in as- sociation with hydroxychloroquine treatment for rheumatoid arthritis. Rheumatology (Oxford) 2002;41: 473-4
  8. Perez-Ezquerra PR, de Barrio Fernandez M, de Castro Martinez FJ, Ruiz Hornillos FJ, Prieto Garcia A. Delayed hypersensitivity to hydroxychloroquine manifested by two different types of cutaneous eruptions in the same patient. Allergol Immunopathol (Madr) 2006;34:174-5 9. Mukasa Y, Craven N. Management of toxic epidermal necrolysis and related syndromes. Postgrad Med J 2008;84:60-5
  9. Letko E, Papaliodis DN, Papaliodis GN, Daoud YJ, Ahmed AR, Foster CS. Stevens-Johnson syndrome and toxic epidermal necrolysis: a review of the literature. Ann Allergy Asthma Immunol 2005;94:419-36
  10. French LE. Toxic epidermal necrolysis and Stevens- Johnson syndrome: our current understanding. Allergol Int 2006;55:9-16
  11. Leaute-Labreze C, Lamireau T, Chawki D, Maleville J, Taieb A. Diagnosis, classification, and management of erythema multiforme and Stevens-Johnson syndrome. Arch Dis Child 2000;83:347-52
  12. Walsh SA, Creamer D. Drug reaction with eosinophilia and systemic symptoms (DRESS): a clinical update and review of current thinking. Clin Exp Dermatol 2011;36:6-11
  13. Palmieri T, Greenhalgh DG, Saffle JR, Spence RJ, Peck MD, Jeng JC, et al. A multicenter review of toxic epidermal necrolysis treated in US burn centers at the end of the twentieth century. J Burn Care Rehabil 2002;23:87-96
  14. Dalli RL, Kumar R, Kennedy