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Journals / Sağlık Akademisyenleri Dergisi / 2026 / Cilt: 13 Sayı: 1

The relationship between intermıttent fasting and type 2 diabetes: A traditional review

Aralıklı oruç ile tip 2 diyabet ilişkisi: geleneksel derleme

Seyit Ramazan Karadoğan(Eğirdir Kemik Eklem Hastalıkları Tedavi ve Rehabilitasyon Hastanesi)0000-0001-5413-8484
Eren Canbolat(ANKARA ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİ, BESLENME VE DİYETETİK BÖLÜMÜ, BESLENME VE DİYETETİK ANABİLİM DALI)0000-0001-6250-2303
Pages
169–179
Publication Date
2026-03-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, intermittent fasting, when carefully planned and supported by healthcare professionals, can be an effective strategy in the management of type 2 diabetes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Type 2 diabetes has become a major global public health concern due to its rapidly increasing prevalence.
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Key Findings & Data:This review evaluates the effects of different intermittent fasting protocols, including alternate-day fasting, periodic fasting, and time-restricted feeding, on type 2 diabetes.
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Conclusion & Impact:In conclusion, intermittent fasting, when carefully planned and supported by healthcare professionals, can be an effective strategy in the management of type 2 diabetes.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Aralıklı Oruç · Tip 2 Diyabet · Glisemik Kontrol

Abstract

Type 2 diabetes has become a major global public health concern due to its rapidly increasing prevalence. Medical nutrition therapy plays a fundamental role in the management of diabetes, and the exploration of new, sustainable dietary approaches has gained significance. In recent years, intermittent fasting diets have garnered attention for their potential to improve glycemic control, enhance insulin sensitivity, and promote weight reduction. This review evaluates the effects of different intermittent fasting protocols, including alternate-day fasting, periodic fasting, and time-restricted feeding, on type 2 diabetes. Evidence from the literature suggests that intermittent fasting can significantly lower HbA1c levels, improve insulin resistance, and reduce fasting blood glucose levels. Additionally, intermittent fasting has been shown to activate metabolic processes such as AMPK activation and autophagy, contributing to enhanced insulin sensitivity. However, potential risks such as hypoglycemia, dehydration, and micronutrient deficiencies, particularly in insulin-treated patients, emphasize the necessity for medical supervision during implementation. The limitations of existing studies, including small sample sizes and short follow-up durations, highlight the need for further research. In conclusion, intermittent fasting, when carefully planned and supported by healthcare professionals, can be an effective strategy in the management of type 2 diabetes. Nonetheless, larger-scale, long-term randomized controlled trials are essential to confirm its safety, sustainability, and efficacy across diverse populations.

Özet

Tip 2 diyabet, tüm dünyada hızla artan prevalansı ile önemli bir halk sağlığı sorunu haline gelmiştir. Diyabetin yönetiminde tıbbi beslenme tedavisi temel bir rol oynamakta olup, yeni ve sürdürülebilir beslenme modellerinin araştırılması önem kazanmaktadır. Son yıllarda aralıklı oruç diyetleri, glisemik kontrolü iyileştirme, insülin duyarlılığını artırma ve vücut ağırlığını azaltma gibi faydaları nedeniyle dikkat çekmektedir. Bu derlemede, alternatif gün orucu, periyodik oruç ve zaman kısıtlı aralıklı oruç gibi farklı aralıklı oruç modellerinin tip 2 diyabet üzerindeki etkileri değerlendirilmiştir. Literatürde aralıklı orucun HbA1c düzeylerini düşürdüğü, insülin direncini azalttığı ve açlık kan glikozunda iyileşmeler sağladığı gösterilmiştir. Ayrıca metabolik süreçlerde AMPK aktivasyonu ve otofaji mekanizmalarının aralıklı oruçla tetiklendiği ve bu yolla insülin duyarlılığının artırıldığı ortaya konmuştur. Bununla birlikte, aralıklı oruç uygulamalarının hipoglisemi, dehidratasyon ve besin ögesi eksiklikleri gibi olası riskleri olduğu ve özellikle insülin kullanan bireylerde tıbbi gözetim altında uygulanması gerektiği vurgulanmaktadır. Mevcut çalışmaların genellikle küçük örneklem grupları ve kısa süreli takiplerle sınırlı olması, uzun vadeli güvenilirlik ve etkinlik verileri eksikliğine yol açmaktadır. Sonuç olarak, aralıklı oruç dikkatli bir planlama, profesyonel destek ve bireyselleştirilmiş yaklaşımlar eşliğinde tip 2 diyabet yönetiminde etkili bir strateji olarak kullanılabilir. Ancak bu konuda daha büyük örneklemli, uzun dönemli randomize kontrollü çalışmalara ihtiyaç vardır.

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Cite This Article

Karadoğan, S. R., Canbolat, E. (2026). The relationship between intermıttent fasting and type 2 diabetes: A traditional review. Sağlık Akademisyenleri Dergisi, Cilt: 13 Sayı: 1, 169–179. https://doi.org/10.52880/sagakaderg.1690303

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