Journals / Sabuncuoglu Serefeddin Health Sciences / 2026 / Cilt: 6 Sayı: 1

Evaluation of Drug-Drug Interactions in Patients Admitting to the Ear Nose and Throat Clinic

Serkan Ceyhan(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ESKİŞEHİR ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ)0000-0001-6497-0629
Sinem Gürcü(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ESKİŞEHİR ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0001-8534-7369
Pages
20–27
Publication Date
2024-08-30
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

More attention should be paid to drug interactions in these patients, especially physicians and pharmacists.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: Drug interactions are effects that change the effect of the drug and therefore on the patient, mostly due to the use of drugs together at the same or recent times.
📊
Key Findings & Data:Materials and Methods: The prescriptions of 106 patients who applied to the ear, nose, and throat outpatient clinic between January and December 2021 were examined retrospectively.
💡
Conclusion & Impact:More attention should be paid to drug interactions in these patients, especially physicians and pharmacists.
🔬Design:Araştırma Makalesi
📍Scope:2021 Verileri
⚙️Variables:Drug interactions · Ear-nose-throat diseases · Antihistamines

Abstract

Introduction: Drug interactions are effects that change the effect of the drug and therefore on the patient, mostly due to the use of drugs together at the same or recent times. Drug interactions can cause serious consequences such as the development of adverse events, ineffectiveness of the treatment, or mortality. Materials and Methods: The prescriptions of 106 patients who applied to the ear, nose, and throat outpatient clinic between January and December 2021 were examined retrospectively. Results: 106 prescriptions were included in the study. Twelve major, 19 moderate, and 9 minor interactions were detected in 106 prescriptions. Conclusion: Although there are relatively few interactions compared to studies conducted with other patient groups, interactions can affect the clinical status of the patient. More attention should be paid to drug interactions in these patients, especially physicians and pharmacists.

🔖

Cite This Article

Ceyhan, S., Gürcü, S. (2024). Evaluation of Drug-Drug Interactions in Patients Admitting to the Ear Nose and Throat Clinic. Sabuncuoglu Serefeddin Health Sciences, Cilt: 6 Sayı: 1, 20–27. https://doi.org/10.55895/sshs.1427187

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Alvim, M. M., Silva, L. A. D., Leite, I. C. G., & Silvério, M. S. (2015). Adverse events caused by potential drug-drug interactions in an intensive care unit of a teaching hospital. Revista Brasileira de terapia intensiva, 27, 353-359.
  2. Andrade, P. H. S., Santos, A. D. S., Souza, C. A. S., Lobo, I. M. F., & da Silva, W. B. (2017). Risk factors for adverse drug reactions in pediatric inpatients: a systematic review. Therapeutic advances in drug safety, 8(6), 199-210.
  3. Antimicrobial Resistance Polict Insight. Accessed December 24, 2023. Retrieved from: https://www.oecd.org/health/health-systems/AMR-Policy-Insights November2016.pdf
  4. Bhat, G. M. N., Holla, R., & Kamath P. S. D. (2015). A study of prescription pattern in the drug therapy of ear, nose, and throat infections at a tertiary care hospital in Mangalore. International Journal of Basic & Clinical Pharmacology, 4(4), 686–90.
  5. Bindu, S., Mazumder, S., & Bandyopadhyay, U. (2020). Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective. Biochemical pharmacology, 180, 114147.
  6. Caffarelli, C., Giannetti, A., Giannì, G., & Ricci, G. (2023). Anti-inflammatory and biologic drugs for atopic dermatitis: a therapeutic approach in children and adolescents. Frontiers in Medicine, 10.
  7. Delafuente, J. C. (2003). Understanding and preventing drug interactions in elderly patients. Critical reviews in oncology/hematology, 48(2), 133-143.
  8. Hunter, L. J., Wood, D. M., & Dargan, P. I. (2011). The patterns of toxicity and management of acute nonsteroidal anti-inflammatory drug (NSAID) overdose. Open access emergency medicine: OAEM, 3, 39.
  9. Kay, G. G. (2000). The effects of antihistamines on cognition and performance. Journal of Allergy and Clinical Immunology, 105(6), S622-S627.
  10. Lin, C. F., Wang, C. Y., & Bai, C. H. (2011). Polypharmacy, aging and potential drug-drug interactions in outpatients in Taiwan: a retrospective computerized screening study. Drugs & aging, 28, 219-225.
  11. Seynaeve, S., Verbrugghe, W., Claes, B., Vandenplas, D., Reyntiens, D., & Jorens, P. G. (2011). Adverse drug events in intensive care units: a cross-sectional study of prevalence and risk factors. American Journal of Critical Care, 20(6), e131-e140.
  12. Turkish Pharmaceutical Market Observation Report. Accessed December 24, 2023. Retrieved from: https://titck.gov.tr/storage/Archive/2019/.pdf
  13. Van Leeuwen, R. W. F., Swart, E. L., Boven, E., Boom, F. A., Schuitenmaker, M. G., & Hugtenburg, J. G. (2011). Potential drug interactions in cancer therapy: a prevalence study using an advanced screening method. Annals of oncology, 22(10), 2334-2341.
  14. Wang, H., Shi, H., Wang, N., Wang, Y., Zhang, L., Zhao, Y., & Xie, J. (2022). Prevalence of potential drug− drug interactions in the cardiothoracic intensive care unit patients in a Chinese tertiary care teaching hospital. BMC Pharmacology and Toxicology, 23(1), 1-6.
  15. Yunes, L. P., Coelho, T. D. A., & de Almeida, S. M. (2011). e Serviços de Saúde, 2(3):23-6.