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Journals / Astım Allerji İmmünoloji / 2015 / Cilt: 13 - Sayı: 3

Four child cases diagnosed with DRESS syndrome

DRESS sendromu tanısı konulan dört çocuk olgu DRESS sendromu tanısı konulan dört çocuk olgu

Hacer İlbilge ERTOY KARAGÖL
Özlem YILMAZ
Erdem TOPAL
Arzu BAKIRTAŞ
Pages
138–143
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We aimed to discuss DRESS syndrome in children with clinical and laboratory characteristics, diagnosis and treatment of those cases whose ages vary between 7 and 14 years old

📌 3 Key Takeaways

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Objective & Hypothesis:"Drug Reaction with Eosinophilia and Systemic Symptoms'' (DRESS) syndrome, is characterized with fewer, extensive mucocutaneous rash, facial oedema, lymphadenopathy, eosinophilia and/or other hematological abnormalities and internal organ involvement that typically emerge following the latent period that varies between 2-6 weeks aft er the beginning of drug treatment.
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Key Findings & Data:It is known that this syndrome, which is assessed among severe cutaneous adverse drug reactions, is less common in children than adults.
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Conclusion & Impact:We aimed to discuss DRESS syndrome in children with clinical and laboratory characteristics, diagnosis and treatment of those cases whose ages vary between 7 and 14 years old
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

"Drug Reaction with Eosinophilia and Systemic Symptoms'' (DRESS) syndrome, is characterized with fewer, extensive mucocutaneous rash, facial oedema, lymphadenopathy, eosinophilia and/or other hematological abnormalities and internal organ involvement that typically emerge following the latent period that varies between 2-6 weeks aft er the beginning of drug treatment. It is known that this syndrome, which is assessed among severe cutaneous adverse drug reactions, is less common in children than adults. Although many defi ning adult studies about DRESS syndrome exist, a limited number of studies in which child cases have been evaluated are available. Th erefore, we off ered four child cases that fi rst of which is correlated with sulfonamide derivate use of antibiotics and the others of which are diagnosed with use of anticonvulsant dependent DRESS syndrome in our clinic. We aimed to discuss DRESS syndrome in children with clinical and laboratory characteristics, diagnosis and treatment of those cases whose ages vary between 7 and 14 years old

Özet

Drug Reaction with Eosinophilia and Systemic Symptoms'' (DRESS) sendromu, tipik olarak ilaç başlandıktan sonra 2-6 haft a arasında değişen latent periyodu takiben ortaya çıkan ateş, yaygın mukokütanöz döküntü, yüzde ödem, lenfadenopati, eozinofili ve/veya diğer hematolojik anormallikler ve iç organ tutulumlarıyla karakterize olup, şiddetli kütanöz ilaç reaksiyonları arasında değerlendirilir. Bu sendromun çocuklarda erişkinlere göre daha seyrek görüldüğü bilinmektedir. DRESS sendromu ile ilgili çok sayıda tanımlayıcı erişkin çalışması olmasına rağmen DRESS sendromu tanısı konulan çocuk olguların değerlendirildiği sınırlı sayıda çalışma mevcuttur. Biz de bu nedenle kliniğimizde ilki sülfonamid türevi antibiyotik kullanımı ile ilişkilendirilen, diğerleri antikonvülzan kullanımına bağlı DRESS sendromu tanısı konulan dört çocuk olguyu sunduk. Yaşları 7-14 arasında değişen bu olguların klinik ve laboratuvar özellikleri, tanı ve tedavisi eşliğinde çocuklarda DRESS sendromunu tartışmayı amaçladık

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Cite This Article

KARAGÖL, H. İ. E., YILMAZ, Ö., TOPAL, E., BAKIRTAŞ, A. (2015). Four child cases diagnosed with DRESS syndrome. Astım Allerji İmmünoloji, Cilt: 13 - Sayı: 3, 138–143. https://ajindex.com/articles/151225

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