Journals / Journal of Health Sciences and Medicine / 2026 / Volume: 9 Issue: 3

Left isolated inguinal endometriosis without pelvic endometriosis associated with PCOS and review of literature

Pelvik endometriozisin eşlik etmediği PKOS ile birliktelik gösteren sol inguinal endometriosis

Bilge Sezin Akhan(Ankara Atatürk Sanatorium Training and Research Hospital, Department of Radiology,)0000-0002-4647-7053
Hakan Ertürk(Ankara Atatürk Sanatorium Training and Research Hospital, Department of Radiology)0000-0002-5730-9215
Pages
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Publication Date
2026-05-19
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

PCOS can be associated with inguinal endometriosis even without pelvic endometriosis.

📌 3 Key Takeaways

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Objective & Hypothesis:The coexistence of polycystic ovary syndrome (PCOS) and endometriosis is rare.
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Key Findings & Data:Inguinal endometriosis (IEM) is an uncommon extrapelvic form of endometriosis, accounting for approximately 0.3-0.6% of all cases.
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Conclusion & Impact:PCOS can be associated with inguinal endometriosis even without pelvic endometriosis.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Endometriosis · PCOS · canal of Nuck

Abstract

The coexistence of polycystic ovary syndrome (PCOS) and endometriosis is rare. Inguinal endometriosis (IEM) is an uncommon extrapelvic form of endometriosis, accounting for approximately 0.3-0.6% of all cases. It typically presents as inguinal swelling with cyclical pain and enlargement related to the menstrual cycle. A 40-year-old woman with a known diagnosis of type 1 PCOS and a history of two cesarean sections presented with a painful mass in the left inguinal region. The pain and swelling were cyclical in nature and became more pronounced during menstruation. The patient reported that her symptoms had worsened following the discontinuation of combined oral contraceptives, which she had been using for PCOS management. Physical examination revealed a tender mass in the left groin. Ultrasonography and magnetic resonance imaging demonstrated a lesion in the left inguinal region suggestive of endometriosis. Based on clinical and radiological findings, surgical intervention was planned. The patient underwent laparotomy, during which the left round ligament and the associated mass were completely excised. Intraoperative findings were consistent with endometriosis. The postoperative course was uneventful. Histopathological examination of the excised tissue confirmed the diagnosis of endometriosis. PCOS can be associated with inguinal endometriosis even without pelvic endometriosis.

Özet

Özet İnguinal endometriozisin prevalansı %0,3-06 oranlarında çok nadir görülen ekstrapelvik endometriozisdir. Ektopik endometrial doku hormon duyarlı olduğu için ekstpelvik endometriozis vakalarında lezyonun olduğu bölgede menstruasyon döneminde ağrı ve şişlik ortaya çıkmaktadır. Her ay bu durumun tekrar etmesi lezyon bölgesinde artmış enflamasyon, fibrozis ve ağrı ile sonuçlanmaktadır. PKOS ve inguinal endometriozis birlikteliği çok nadir görülmektedir. Vaka sunumu İki sezaryen öyküsü olan 40 yaşında kadın hasta, adet dönemleriyle çakışan tekrarlayan sol taraflı kasık ağrısı ve kitle öyküsüyle başvurdu. Rotterdam kriterlerine göre hastaya önceki takiplerinde tip 1 PKOS tanısı konmuştu. PKOS nedeniyle uzun yıllardır kombine oral kontraseptif (KOK) kullanıyordu. KOK kullanımını bıraktıktan sonra kasık ağrısı ve sol kasıkta mons pubis yakınında adet dönemlerinde artan ve diğer zamanlarda devam eden elle hissedilen bir kitleden şikayetçi oldu. Tanı, daha sonra yapılan abdominopelvik manyetik rezonans görüntüleme (MRG) incelemesiyle doğrulandı. MRG sol kasık bölgesinde endometriotik kitle tespit edildi ve sol round ligamanın ve ilişkili kasık kitlesinin laparotomik rezeksiyonu gerçekleştirildi. Ameliyat sırasındaki bulgular endometriozis ile uyumluydu. Ameliyat öncesi görüntüleme yararlıdır, ancak kesin tanı ancak cerrahi eksizyon ve histopatolojiden sonra doğrulanabilir. Sonuç: Üreme çağındaki kadınlarda İEM ve PKOS birlikte görülebilir, ancak bu durumçok nadirdir. Adet kanamasıyla ilişkili ağrılı kitleleri olan üreme çağındaki kadınlarda inguinal endometriozis düşünülmelidir.

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Cite This Article

Kaya, C., Akhan, B. S., Ertürk, H. (2026). Left isolated inguinal endometriosis without pelvic endometriosis associated with PCOS and review of literature. Journal of Health Sciences and Medicine, Volume: 9 Issue: 3. https://doi.org/10.32322/jhsm.1839088

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References (26)

  1. Teede HJ, Misso ML, Costello MF, et al. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril. 2018;110(3):364-379. doi:10.1016/j.fertnstert.2018.05.004
  2. Mascaretti G, Di Berardino C, Mastrocola N, et al. Endometriosis: rare localizations in two cases. Clin Exp Obstet Gynecol. 2007;34:123-125.
  3. Mu B, Zhang Z, Liu C, et al. Long term follow-up of inguinal endometriosis. BMC Womens Health. 2021;21(1):90. doi:10.1186/s12905-021-01235-2
  4. Zarcone R, Longo M, Ferrara G, Cardone A. Association between inguinal endometriosis and polycystic ovary. Minerva Ginecol 1992; 44(4):197-200
  5. Lo L, Lee R. Spontaneous cutaneous endometriosis of the mons pubis: diagnosis, treatment, and review of the literature. J Endometr Pelvic Pain Dis. 2018;10:36-38.
  6. Watanabe Y, Suzuki R, Kinoshita M, Hirota M Inguinal endometriosis with a disappearing mass preoperatively: a case report. Int J Surg Case Rep. 2022;91:106781. doi:10.1016/j.ijscr.2022.106781
  7. Zarcone R, Longo M, Ferrara G, Cardone A. Association between inguinal endometriosis and polycyctic ovary. Minerva Ginecol. 1992; 44(4):197-200.
  8. Tan H, Long P, Xiao H.Dissecting the shared genetic architecture between endometriosis and polycystic ovary syndrome. Front Endocrinol (Lausanne). 2024;15:1359236. doi:10.3389/fendo.2024.1359236
  9. Dinsdale NL, Crespi BJ. Endometriosis and polycystic ovary syndrome are diametric disorders. Evol Appl. 2021;14:1693-1715. doi:10.1111/eva. 13244
  10. Hager M, Wenzl R, Riesenhuber S, et al. The prevalence of incidental endometriosis in women undergoing laparoscopic ovarian drilling for clomiphene-resistant polycystic ovary syndrome: a retrospective cohort study and meta-analysis. J Clin Med. 2019;8(8):1210. doi:10.3390/jcm 8081210
  11. Haghgoo A, Faegh A, Mostafavi SRS, Zamani HR, Ghahremani M. Inguinal endometriosis: a case series and review of the literature. J Med Case Rep. 2024;18(1):83. doi:10.1186/s13256-024-04400-x
  12. Andres MP, Arcoverde FVL, Souza CCC, Fernandes LFC, Abrão MS, Kho RM. Extrapelvic endometriosis: a systematic review. J Minim Invasive Gynecol. 2020;27(2):373-389. doi:10.1016/j.jmig.2019.10.004
  13. Dalkalitsis A, Salta S, Tsakiridis I, et al. Inguinal endometriosis: a systematic review. Taiwan J Obstet Gynecol. 2022;61(1):24-33. doi:10. 1016/j.tjog.2021.11.007
  14. Prodromidou A, Pandraklakis A, Rodolakis A, Thomakos N. endometriosis of the canal of nuck: a systematic review of the literature. Diagnostics (Basel). 2020;11(1):3. doi:10.3390/diagnostics11010003
  15. Candiani GB, Vercellini P, Fedele L, Vendola N, Carinelli S, Scaglione V. Inguinal endometriosis: pathogenetic and clinical implications. Obstet Gynecol. 1991;78(2):191-194.
  16. Lipschultz RA, Lee TT. Inguinal canal endometriosis. Fertil Steril. 2025;124(2):381-382. doi:10.1016/j.fertnstert.2025.03.035
  17. Figueira PG, Abrão MS, Krikun G, Taylor HS. Stem cells in endometrium and their role in the pathogenesis of endometriosis. Ann N Y Acad Sci. 2011;1221(1):10-17. doi:10.1111/j.1749-6632.2011.05969.x
  18. Bonavina G, Taylor HS. Endometriosis-associated infertility: from pathophysiology to tailored treatment. Front Endocrinol (Lausanne). 2022;13:1020827. doi:10.3389/fendo.2022.1020827
  19. Gaeta M, Minutoli F, Mileto A, et al. Nuck canal endometriosis: MR imaging findings and clinical features. Abdom Imaging. 2010;35:737-741. doi:10.1007/s00261-010-9607-7
  20. Çayır D, Araz M, Apaydın M, Çakal E. Inguinal endometriosis visualized on i-131 whole body scan. Mol Imaging Radionucl Ther. 2018;27(1):52-54. doi:10.4274/mirt.77044
  21. Niitsu H, Tsumura H, Kanehiro T, Yamaoka H, Taogoshi H, Murao N. Clinical characteristics and surgical treatment for inguinal endometriosis in young women of reproductive age. Dig Surg. 2019;36(2): 166-172. doi:10.1159/000489827
  22. Tilva H, Tayade S, Kanjiya A. Contemporary review of masses in the canal of Nuck. Cureus. 2023;15(3):e36722. doi:10.7759/cureus.36722
  23. Hirata T, Koga K, Osuga Y. Extra-pelvic endometriosis: a review. Reprod Med Biol. 2020;19(4):323-333. doi:10.1002/rmb2.12340
  24. Fong KNY, Lau TWS, Mak CCC, Lui KW. Inguinal endometriosis: a differential diagnosis of right groin swelling in women of reproductive age. BMJ Case Rep. 2019;12(8):e229864. doi:10.1136/bcr-2019-229864
  25. Arakawa T, Hirata T, Koga K, et al. Clinical aspects and management of inguinal endometriosis: a case series of 20 patients. J Obstet Gynaecol Res. 2019;45(10):2029-2036. doi:10.1111/jog.14059
  26. Takatsuka S, Kataoka H, Ito F, Shimura K, Mori T. Pathogenesis, diagnosis, and management of inguinal endometriosis: a case series of six patients. Reprod Sci. 2025;32(3):647-654. doi:10.1007/s43032-025-01796-9